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253 related items for PubMed ID: 8564846

  • 1. Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis.
    Wahl AF, Donaldson KL, Fairchild C, Lee FY, Foster SA, Demers GW, Galloway DA.
    Nat Med; 1996 Jan; 2(1):72-9. PubMed ID: 8564846
    [Abstract] [Full Text] [Related]

  • 2. Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
    Woods CM, Zhu J, McQueney PA, Bollag D, Lazarides E.
    Mol Med; 1995 Jul; 1(5):506-26. PubMed ID: 8529117
    [Abstract] [Full Text] [Related]

  • 3. Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.
    Bacus SS, Gudkov AV, Lowe M, Lyass L, Yung Y, Komarov AP, Keyomarsi K, Yarden Y, Seger R.
    Oncogene; 2001 Jan 11; 20(2):147-55. PubMed ID: 11313944
    [Abstract] [Full Text] [Related]

  • 4. Taxol-induced cell cycle arrest and apoptosis: dose-response relationship in lung cancer cells of different wild-type p53 status and under isogenic condition.
    Das GC, Holiday D, Gallardo R, Haas C.
    Cancer Lett; 2001 Apr 26; 165(2):147-53. PubMed ID: 11275363
    [Abstract] [Full Text] [Related]

  • 5. Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis.
    Vikhanskaya F, Vignati S, Beccaglia P, Ottoboni C, Russo P, D'Incalci M, Broggini M.
    Exp Cell Res; 1998 May 25; 241(1):96-101. PubMed ID: 9633517
    [Abstract] [Full Text] [Related]

  • 6. Mechanisms of Taxol-induced cell death are concentration dependent.
    Torres K, Horwitz SB.
    Cancer Res; 1998 Aug 15; 58(16):3620-6. PubMed ID: 9721870
    [Abstract] [Full Text] [Related]

  • 7. Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells: association with bcl-2 phosphorylation but neither activation of p53 nor G2/M cell cycle arrest.
    Roth W, Wagenknecht B, Grimmel C, Dichgans J, Weller M.
    Br J Cancer; 1998 Aug 15; 77(3):404-11. PubMed ID: 9472635
    [Abstract] [Full Text] [Related]

  • 8. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.
    Giannakakou P, Robey R, Fojo T, Blagosklonny MV.
    Oncogene; 2001 Jun 28; 20(29):3806-13. PubMed ID: 11439344
    [Abstract] [Full Text] [Related]

  • 9. Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation.
    Rakovitch E, Mellado W, Hall EJ, Pandita TK, Sawant S, Geard CR.
    Int J Radiat Oncol Biol Phys; 1999 Jul 15; 44(5):1119-24. PubMed ID: 10421546
    [Abstract] [Full Text] [Related]

  • 10. p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells.
    Hirose Y, Berger MS, Pieper RO.
    Cancer Res; 2001 Mar 01; 61(5):1957-63. PubMed ID: 11280752
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of p21(waf1) decreases G2-M arrest and apoptosis induced by paclitaxel in human sarcoma cells lacking both p53 and functional Rb protein.
    Li W, Fan J, Banerjee D, Bertino JR.
    Mol Pharmacol; 1999 Jun 01; 55(6):1088-93. PubMed ID: 10347252
    [Abstract] [Full Text] [Related]

  • 12. Increased sensitivity of p53-deficient cells to anticancer agents due to loss of Pms2.
    Fedier A, Ruefenacht UB, Schwarz VA, Haller U, Fink D.
    Br J Cancer; 2002 Oct 21; 87(9):1027-33. PubMed ID: 12434296
    [Abstract] [Full Text] [Related]

  • 13. Caffeine and the G2/M block override: a concept resulting from a misleading cell kinetic delay, independent of functional p53.
    Deplanque G, Céraline J, Mah-Becherel MC, Cazenave JP, Bergerat JP, Klein-Soyer C.
    Int J Cancer; 2001 Nov 01; 94(3):363-9. PubMed ID: 11745415
    [Abstract] [Full Text] [Related]

  • 14. The mammalian metabolite, 2-methoxyestradiol, affects P53 levels and apoptosis induction in transformed cells but not in normal cells.
    Seegers JC, Lottering ML, Grobler CJ, van Papendorp DH, Habbersett RC, Shou Y, Lehnert BE.
    J Steroid Biochem Mol Biol; 1997 Jul 01; 62(4):253-67. PubMed ID: 9408079
    [Abstract] [Full Text] [Related]

  • 15. Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay.
    Powell SN, DeFrank JS, Connell P, Eogan M, Preffer F, Dombkowski D, Tang W, Friend S.
    Cancer Res; 1995 Apr 15; 55(8):1643-8. PubMed ID: 7712468
    [Abstract] [Full Text] [Related]

  • 16. Etoposide induces G2/M arrest and apoptosis in neural progenitor cells via DNA damage and an ATM/p53-related pathway.
    Nam C, Doi K, Nakayama H.
    Histol Histopathol; 2010 Apr 15; 25(4):485-93. PubMed ID: 20183801
    [Abstract] [Full Text] [Related]

  • 17. Deoxypodophyllotoxin induces G2/M cell cycle arrest and apoptosis in HeLa cells.
    Shin SY, Yong Y, Kim CG, Lee YH, Lim Y.
    Cancer Lett; 2010 Jan 28; 287(2):231-9. PubMed ID: 19616373
    [Abstract] [Full Text] [Related]

  • 18. Micromolar taxol, with or without hyperthermia, induces mitotic catastrophe and cell necrosis in HeLa cells.
    Michalakis J, Georgatos SD, Romanos J, Koutala H, Georgoulias V, Tsiftsis D, Theodoropoulos PA.
    Cancer Chemother Pharmacol; 2005 Dec 28; 56(6):615-22. PubMed ID: 16025289
    [Abstract] [Full Text] [Related]

  • 19. Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe.
    Tse AN, Schwartz GK.
    Cancer Res; 2004 Sep 15; 64(18):6635-44. PubMed ID: 15374978
    [Abstract] [Full Text] [Related]

  • 20. Down regulation of p53 with HPV E6 delays and modifies cell death in oxidant response of human diploid fibroblasts: an apoptosis-like cell death associated with mitosis.
    Chen QM, Merrett JB, Dilley T, Purdom S.
    Oncogene; 2002 Aug 08; 21(34):5313-24. PubMed ID: 12149652
    [Abstract] [Full Text] [Related]

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