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Journal Abstract Search

206 related items for PubMed ID: 8567676

  • 1. Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.
    Bhattacharyya DK, Lecomte M, Rieke CJ, Garavito M, Smith WL.
    J Biol Chem; 1996 Jan 26; 271(4):2179-84. PubMed ID: 8567676
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  • 2. The role of arginine 120 of human prostaglandin endoperoxide H synthase-2 in the interaction with fatty acid substrates and inhibitors.
    Rieke CJ, Mulichak AM, Garavito RM, Smith WL.
    J Biol Chem; 1999 Jun 11; 274(24):17109-14. PubMed ID: 10358065
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  • 5. Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
    Pouplana R, Lozano JJ, Ruiz J.
    J Mol Graph Model; 2002 Jan 11; 20(4):329-43. PubMed ID: 11858641
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  • 11. Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents.
    Guo Q, Wang LH, Ruan KH, Kulmacz RJ.
    J Biol Chem; 1996 Aug 09; 271(32):19134-9. PubMed ID: 8702589
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  • 12. Characterization of the tyrosyl radicals in ovine prostaglandin H synthase-1 by isotope replacement and site-directed mutagenesis.
    Tsai A, Hsi LC, Kulmacz RJ, Palmer G, Smith WL.
    J Biol Chem; 1994 Feb 18; 269(7):5085-91. PubMed ID: 8106487
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  • 13. Conversion of prostaglandin G/H synthase-1 into an enzyme sensitive to PGHS-2-selective inhibitors by a double His513 --> Arg and Ile523 --> val mutation.
    Wong E, Bayly C, Waterman HL, Riendeau D, Mancini JA.
    J Biol Chem; 1997 Apr 04; 272(14):9280-6. PubMed ID: 9083063
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  • 14. Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products.
    Thuresson ED, Lakkides KM, Smith WL.
    J Biol Chem; 2000 Mar 24; 275(12):8501-7. PubMed ID: 10722687
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  • 16. The dynamics of prostaglandin H synthases. Studies with prostaglandin h synthase 2 Y355F unmask mechanisms of time-dependent inhibition and allosteric activation.
    So OY, Scarafia LE, Mak AY, Callan OH, Swinney DC.
    J Biol Chem; 1998 Mar 06; 273(10):5801-7. PubMed ID: 9488715
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  • 17. Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2.
    Tsai AL, Palmer G, Wu G, Peng S, Okeley NM, van der Donk WA, Kulmacz RJ.
    J Biol Chem; 2002 Oct 11; 277(41):38311-21. PubMed ID: 12167656
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  • 19. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases.
    DeWitt DL, el-Harith EA, Kraemer SA, Andrews MJ, Yao EF, Armstrong RL, Smith WL.
    J Biol Chem; 1990 Mar 25; 265(9):5192-8. PubMed ID: 2108169
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