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Journal Abstract Search

318 related items for PubMed ID: 8568814

  • 21. Synthesis of the butanamide derivative S 19812, a new dual inhibitor of cyclooxygenase and lipoxygenase pathways.
    Tordjman C, Sauveur F, Droual M, Briss S, Andre N, Bellot I, Deschamps C, Wierzbicki M.
    Arzneimittelforschung; 2003; 53(11):774-9. PubMed ID: 14677373
    [Abstract] [Full Text] [Related]

  • 22. 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
    Boehm JC, Smietana JM, Sorenson ME, Garigipati RS, Gallagher TF, Sheldrake PL, Bradbeer J, Badger AM, Laydon JT, Lee JC, Hillegass LM, Griswold DE, Breton JJ, Chabot-Fletcher MC, Adams JL.
    J Med Chem; 1996 Sep 27; 39(20):3929-37. PubMed ID: 8831759
    [Abstract] [Full Text] [Related]

  • 23. Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA, Abdellatif KR, Dong Y, Das D, Suresh MR, Knaus EE.
    J Med Chem; 2009 Mar 26; 52(6):1525-9. PubMed ID: 19296694
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  • 24. Discovery and biological evaluation of a novel class of dual microsomal prostaglandin E2 synthase-1/5-lipoxygenase inhibitors based on 2-[(4,6-diphenethoxypyrimidin-2-yl)thio]hexanoic acid.
    Hieke M, Greiner C, Dittrich M, Reisen F, Schneider G, Schubert-Zsilavecz M, Werz O.
    J Med Chem; 2011 Jul 14; 54(13):4490-507. PubMed ID: 21591611
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  • 25. Synthesis and antiinflammatory activity of coumarin derivatives.
    Kontogiorgis CA, Hadjipavlou-Litina DJ.
    J Med Chem; 2005 Oct 06; 48(20):6400-8. PubMed ID: 16190766
    [Abstract] [Full Text] [Related]

  • 26. Outstanding Anti-inflammatory Potential of Selected Asteraceae Species through the Potent Dual Inhibition of Cyclooxygenase-1 and 5-Lipoxygenase.
    Chagas-Paula DA, Oliveira TB, Faleiro DP, Oliveira RB, Costa FB.
    Planta Med; 2015 Sep 06; 81(14):1296-307. PubMed ID: 26227502
    [Abstract] [Full Text] [Related]

  • 27. Conversion of a cyclooxygenase (CO) inhibitor into a 5-lipoxygenase (LO) inhibitor: a general route to novel orally active anti-inflammatory and anti-allergy drugs.
    Kreft AF, Failli AA, Musser JH, Kubrak DM, Banker AL, Steffan R, Demerson CA, Nelson JA, Shah US, Gray W.
    Drugs Exp Clin Res; 1991 Sep 06; 17(8):381-7. PubMed ID: 1822830
    [Abstract] [Full Text] [Related]

  • 28. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.
    Kirchner T, Argentieri DC, Barbone AG, Singer M, Steber M, Ansell J, Beers SA, Wachter MP, Wu W, Malloy E, Stewart A, Ritchie DM.
    J Pharmacol Exp Ther; 1997 Aug 06; 282(2):1094-101. PubMed ID: 9262379
    [Abstract] [Full Text] [Related]

  • 29. N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase.
    Connolly PJ, Wetter SK, Beers KN, Hamel SC, Chen RH, Wachter MP, Ansell J, Singer MM, Steber M, Ritchie DM, Argentieri DC.
    Bioorg Med Chem Lett; 1999 Apr 05; 9(7):979-84. PubMed ID: 10230624
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  • 30. In-vitro versus in-vivo activities of new 5-lipoxygenase inhibitors with antiinflammatory activity.
    Montandon JB, Zijlstra FJ, Wilson JH, Grandjean EM, Cicurel L.
    Int J Tissue React; 1989 Apr 05; 11(3):107-12. PubMed ID: 2515163
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  • 31. Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity.
    Cho YS, Kim CH, Surh JH, Kang NS, Yoo SE, Cheon HG.
    Pharmacology; 2010 Apr 05; 86(2):65-72. PubMed ID: 20639685
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  • 32. Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.
    Lesch CA, Gilbertsen RB, Song Y, Dyer RD, Schrier D, Kraus ER, Sanchez B, Guglietta A.
    J Pharmacol Exp Ther; 1998 Oct 05; 287(1):301-6. PubMed ID: 9765350
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  • 33. Inhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes.
    Abourashed EA, Muhammad I, Resch M, Bauer R, el-Feraly FS, Hufford CD.
    Planta Med; 2001 Jun 05; 67(4):360-1. PubMed ID: 11458456
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  • 34. 1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.
    Boschelli DH, Connor DT, Bornemeier DA, Dyer RD, Kennedy JA, Kuipers PJ, Okonkwo GC, Schrier DJ, Wright CD.
    J Med Chem; 1993 Jun 25; 36(13):1802-10. PubMed ID: 8515419
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  • 35. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM.
    Bioorg Chem; 2017 Jun 25; 72():102-115. PubMed ID: 28390993
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  • 36. Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities.
    Jahng Y, Zhao LX, Moon YS, Basnet A, Kim EK, Chang HW, Ju HK, Jeong TC, Lee ES.
    Bioorg Med Chem Lett; 2004 May 17; 14(10):2559-62. PubMed ID: 15109651
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  • 37. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.
    Shabaan MA, Kamal AM, Faggal SI, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Apr 17; 353(4):e1900308. PubMed ID: 32031284
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  • 38. Nonsteroidal antiinflammatory agents, XVIII: C-5 functionalized 6,7-diphenyl-2,3-dihydro-1H-pyrrolizines as inhibitors of bovine cyclooxygenase and 5-lipoxygenase.
    Dannhardt G, Kiefer W.
    Arch Pharm (Weinheim); 1994 Aug 17; 327(8):509-14. PubMed ID: 7944906
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  • 39. New cyclooxygenase-2/5-lipoxygenase inhibitors. 1. 7-tert-buty1-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: discovery and variation of the 5-keto substituent.
    Janusz JM, Young PA, Ridgeway JM, Scherz MW, Enzweiler K, Wu LI, Gan L, Darolia R, Matthews RS, Hennes D, Kellstein DE, Green SA, Tulich JL, Rosario-Jansen T, Magrisso IJ, Wehmeyer KR, Kuhlenbeck DL, Eichhold TH, Dobson RL, Sirko SP, Farmer RW.
    J Med Chem; 1998 Mar 26; 41(7):1112-23. PubMed ID: 9544211
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  • 40. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    El-Miligy MM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SA.
    Future Med Chem; 2017 Apr 26; 9(5):443-468. PubMed ID: 28362117
    [Abstract] [Full Text] [Related]

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