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Journal Abstract Search

184 related items for PubMed ID: 8568822

  • 1. Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors.
    Glennon RA, Hong SS, Bondarev M, Law H, Dukat M, Rakhi S, Power P, Fan E, Kinneau D, Kamboj R, Teitler M, Herrick-Davis K, Smith C.
    J Med Chem; 1996 Jan 05; 39(1):314-22. PubMed ID: 8568822
    [Abstract] [Full Text] [Related]

  • 2. Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan.
    Leysen JE, Gommeren W, Heylen L, Luyten WH, Van de Weyer I, Vanhoenacker P, Haegeman G, Schotte A, Van Gompel P, Wouters R, Lesage AS.
    Mol Pharmacol; 1996 Dec 05; 50(6):1567-80. PubMed ID: 8967979
    [Abstract] [Full Text] [Related]

  • 3. 2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors.
    Ismaiel AM, Dukat M, Law H, Kamboj R, Fan E, Lee DK, Mazzocco L, Buekschkens D, Teitler M, Pierson ME, Glennon RA.
    J Med Chem; 1997 Dec 19; 40(26):4415-9. PubMed ID: 9435911
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.
    Sternfeld F, Guiblin AR, Jelley RA, Matassa VG, Reeve AJ, Hunt PA, Beer MS, Heald A, Stanton JA, Sohal B, Watt AP, Street LJ.
    J Med Chem; 1999 Feb 25; 42(4):677-90. PubMed ID: 10052975
    [Abstract] [Full Text] [Related]

  • 5. Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.
    Law H, Dukat M, Teitler M, Lee DK, Mazzocco L, Kamboj R, Rampersad V, Prisinzano T, Glennon RA.
    J Med Chem; 1998 Jun 18; 41(13):2243-51. PubMed ID: 9632357
    [Abstract] [Full Text] [Related]

  • 6. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
    Berardi F, Colabufo NA, Giudice G, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1996 Jan 05; 39(1):176-82. PubMed ID: 8568804
    [Abstract] [Full Text] [Related]

  • 7. N-Methyl-5-tert-butyltryptamine: A novel, highly potent 5-HT1D receptor agonist.
    Xu YC, Schaus JM, Walker C, Krushinski J, Adham N, Zgombick JM, Liang SX, Kohlman DT, Audia JE.
    J Med Chem; 1999 Feb 11; 42(3):526-31. PubMed ID: 9986723
    [Abstract] [Full Text] [Related]

  • 8. F 11356, a novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine.
    John GW, Pauwels PJ, Perez M, Halazy S, Le Grand B, Verscheure Y, Valentin JP, Palmier C, Wurch T, Chopin P, Marien M, Kleven MS, Koek W, Assie MB, Carilla-Durand E, Tarayre JP, Colpaert FC.
    J Pharmacol Exp Ther; 1999 Jul 11; 290(1):83-95. PubMed ID: 10381763
    [Abstract] [Full Text] [Related]

  • 9. 3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.
    Chambers MS, Street LJ, Goodacre S, Hobbs SC, Hunt P, Jelley RA, Matassa VG, Reeve AJ, Sternfeld F, Beer MS, Stanton JA, Rathbone D, Watt AP, MacLeod AM.
    J Med Chem; 1999 Feb 25; 42(4):691-705. PubMed ID: 10052976
    [Abstract] [Full Text] [Related]

  • 10. Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines.
    Lesage AS, Wouters R, Van Gompel P, Heylen L, Vanhoenacker P, Haegeman G, Luyten WH, Leysen JE.
    Br J Pharmacol; 1998 Apr 25; 123(8):1655-65. PubMed ID: 9605573
    [Abstract] [Full Text] [Related]

  • 11. 5-(Sulfonyl)oxy-tryptamines and ethylamino side chain restricted derivatives. Structure-affinity relationships for h5-HT1B and h5-HT1D receptors.
    Barf T, Wikström H, Pauwels PJ, Palmier C, Tardif S, Lundmark M, Sundell S.
    Bioorg Med Chem; 1998 Sep 25; 6(9):1469-79. PubMed ID: 9801818
    [Abstract] [Full Text] [Related]

  • 12. Design and synthesis of a series of 6-substituted-2-pyridinylmethylamine derivatives as novel, high-affinity, selective agonists at 5-HT1A receptors.
    Vacher B, Bonnaud B, Funes P, Jubault N, Koek W, Assié MB, Cosi C.
    J Med Chem; 1998 Dec 03; 41(25):5070-83. PubMed ID: 9836623
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the aminomethylchroman derivative BAY x 3702 as a highly potent 5-hydroxytryptamine1A receptor agonist.
    De Vry J, Schohe-Loop R, Heine HG, Greuel JM, Mauler F, Schmidt B, Sommermeyer H, Glaser T.
    J Pharmacol Exp Ther; 1998 Mar 03; 284(3):1082-94. PubMed ID: 9495870
    [Abstract] [Full Text] [Related]

  • 14. Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.
    Vacher B, Bonnaud B, Funes P, Jubault N, Koek W, Assié MB, Cosi C, Kleven M.
    J Med Chem; 1999 May 06; 42(9):1648-60. PubMed ID: 10229633
    [Abstract] [Full Text] [Related]

  • 15. 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.
    Kuipers W, Kruse CG, van Wijngaarden I, Standaar PJ, Tulp MT, Veldman N, Spek AL, IJzerman AP.
    J Med Chem; 1997 Jan 31; 40(3):300-12. PubMed ID: 9022796
    [Abstract] [Full Text] [Related]

  • 16. 5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.
    Barf TA, de Boer P, Wikström H, Peroutka SJ, Swensson K, Ennis MD, Ghazal NB, McGuire JC, Smith MW.
    J Med Chem; 1996 Nov 22; 39(24):4717-26. PubMed ID: 8941384
    [Abstract] [Full Text] [Related]

  • 17. Characteristics of [3H]5-hydroxytryptamine binding to iris-ciliary body tissue of the rabbit.
    Chidlow G, De Santis LM, Sharif NA, Osborne NN.
    Invest Ophthalmol Vis Sci; 1995 Oct 22; 36(11):2238-45. PubMed ID: 7558717
    [Abstract] [Full Text] [Related]

  • 18. The binding of propranolol at 5-hydroxytryptamine1D beta T355N mutant receptors may involve formation of two hydrogen bonds to asparagine.
    Glennon RA, Dukat M, Westkaemper RB, Ismaiel AM, Izzarelli DG, Parker EM.
    Mol Pharmacol; 1996 Jan 22; 49(1):198-206. PubMed ID: 8569707
    [Abstract] [Full Text] [Related]

  • 19. [[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands.
    Modica M, Santagati M, Russo F, Parotti L, De Gioia L, Selvaggini C, Salmona M, Mennini T.
    J Med Chem; 1997 Feb 14; 40(4):574-85. PubMed ID: 9046348
    [Abstract] [Full Text] [Related]

  • 20. Human 5-HT1 receptor subtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells.
    Clawges HM, Depree KM, Parker EM, Graber SG.
    Biochemistry; 1997 Oct 21; 36(42):12930-8. PubMed ID: 9335552
    [Abstract] [Full Text] [Related]

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