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256 related items for PubMed ID: 8569731

  • 1. Regulation of cellular Gs alpha levels and basal adenylyl cyclase activity by expression of the beta 2-adrenoceptor in neuroblastoma cell lines.
    Milligan G, Kim GD, Mullaney I, Adie EJ.
    Mol Cell Biochem; 1995; 149-150():213-6. PubMed ID: 8569731
    [Abstract] [Full Text] [Related]

  • 2. Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.
    Kim GD, Carr IC, Milligan G.
    Biochem J; 1995 May 15; 308 ( Pt 1)(Pt 1):275-81. PubMed ID: 7538756
    [Abstract] [Full Text] [Related]

  • 3. Expression of the human beta 2-adrenoceptor in NCB20 cells results in agonist activation of adenylyl cyclase and agonist-mediated selective down-regulation of Gs alpha.
    Mullaney I, Shah BH, Wise A, Milligan G.
    J Neurochem; 1995 Aug 15; 65(2):545-53. PubMed ID: 7616208
    [Abstract] [Full Text] [Related]

  • 4. Agonist regulation of cellular Gs alpha-subunit levels in neuroblastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human beta 2 adrenoceptor.
    Adie EJ, Milligan G.
    Biochem J; 1994 Jun 15; 300 ( Pt 3)(Pt 3):709-15. PubMed ID: 7516655
    [Abstract] [Full Text] [Related]

  • 5. Regulation of basal adenylate cyclase activity in neuroblastoma x glioma hybrid, NG108-15, cells transfected to express the human beta 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade.
    Adie EJ, Milligan G.
    Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):803-8. PubMed ID: 7980449
    [Abstract] [Full Text] [Related]

  • 6. Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the beta 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity.
    MacEwan DJ, Kim GD, Milligan G.
    Biochem J; 1996 Sep 15; 318 ( Pt 3)(Pt 3):1033-9. PubMed ID: 8836153
    [Abstract] [Full Text] [Related]

  • 7. Analysis of the role of receptor number in defining the intrinsic activity and potency of partial agonists in neuroblastoma x glioma hybrid NG108-15 cells transfected to express differing levels of the human beta 2-adrenoceptor.
    MacEwan DJ, Kim GD, Milligan G.
    Mol Pharmacol; 1995 Aug 15; 48(2):316-25. PubMed ID: 7651365
    [Abstract] [Full Text] [Related]

  • 8. Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma x glioma hybrid, NG108-15 cells.
    Kim GD, Adie EJ, Milligan G.
    Eur J Biochem; 1994 Jan 15; 219(1-2):135-43. PubMed ID: 8306980
    [Abstract] [Full Text] [Related]

  • 9. Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma x glioma hybrid cells transfected to express the beta 2-adrenoceptor.
    Kim GD, Milligan G.
    FEBS Lett; 1994 Nov 28; 355(2):166-70. PubMed ID: 7982493
    [Abstract] [Full Text] [Related]

  • 10. Gs alpha-dependent and -independent desensitisation of prostanoid IP receptor-activated adenylyl cyclase in NG108-15 cells.
    Williams RJ, Kelly E.
    Eur J Pharmacol; 1994 Jul 15; 268(2):177-86. PubMed ID: 7525317
    [Abstract] [Full Text] [Related]

  • 11. Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
    Adie EJ, Mullaney I, McKenzie FR, Milligan G.
    Biochem J; 1992 Jul 15; 285 ( Pt 2)(Pt 2):529-36. PubMed ID: 1379045
    [Abstract] [Full Text] [Related]

  • 12. Efficacy of inverse agonists in cells overexpressing a constitutively active beta2-adrenoceptor and type II adenylyl cyclase.
    Stevens PA, Milligan G.
    Br J Pharmacol; 1998 Jan 15; 123(2):335-43. PubMed ID: 9489623
    [Abstract] [Full Text] [Related]

  • 13. Beta 3-adrenoceptor agonist-induced down-regulation of Gs alpha and functional desensitization in a Chinese hamster ovary cell line expressing a beta 3-adrenoceptor refractory to down-regulation.
    Chambers J, Park J, Cronk D, Chapman C, Kennedy FR, Wilson S, Milligan G.
    Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):973-8. PubMed ID: 7980470
    [Abstract] [Full Text] [Related]

  • 14. Ontogeny of regulatory mechanisms for beta-adrenoceptor control of rat cardiac adenylyl cyclase: targeting of G-proteins and the cyclase catalytic subunit.
    Zeiders JL, Seidler FJ, Slotkin TA.
    J Mol Cell Cardiol; 1997 Feb 01; 29(2):603-15. PubMed ID: 9140819
    [Abstract] [Full Text] [Related]

  • 15. Prostaglandin E1-mediated, cyclic AMP-independent, down-regulation of Gs alpha in neuroblastoma x glioma hybrid cells.
    McKenzie FR, Milligan G.
    J Biol Chem; 1990 Oct 05; 265(28):17084-93. PubMed ID: 2170366
    [Abstract] [Full Text] [Related]

  • 16. Exfoliation of the beta-adrenergic receptor and the regulatory components of adenylate cyclase by cultured rat glioma C6 cells.
    Kassis S, Lauter CJ, Stojanov M, Salem N.
    Biochim Biophys Acta; 1986 May 29; 886(3):474-82. PubMed ID: 2871868
    [Abstract] [Full Text] [Related]

  • 17. Pseudomonas exotoxin A prevents beta-adrenoceptor-induced upregulation of Gi protein alpha-subunits and adenylyl cyclase desensitization in rat heart muscle cells.
    Reithmann C, Gierschik P, Müller U, Werdan K, Jakobs KH.
    Mol Pharmacol; 1990 May 29; 37(5):631-8. PubMed ID: 1971089
    [Abstract] [Full Text] [Related]

  • 18. Expression and characterization of the long and short splice variants of GS alpha in S49 cyc- cells.
    O'Donnell JK, Sweet RW, Stadel JM.
    Mol Pharmacol; 1991 Jun 29; 39(6):702-10. PubMed ID: 1646945
    [Abstract] [Full Text] [Related]

  • 19. Interaction of the beta 2-adrenoceptor with epitope-tagged Gs alpha in NG108-15 cells.
    Mullaney I, Milligan G.
    Biochem Soc Trans; 1995 Feb 29; 23(1):7S. PubMed ID: 7538951
    [No Abstract] [Full Text] [Related]

  • 20. Distinct pathways for beta-adrenoceptor-induced up-regulation of muscarinic acetylcholine receptors and inhibitory G-protein alpha-subunits in chicken cardiomyocytes.
    Reithmann C, Panzner B, Werdan K.
    Naunyn Schmiedebergs Arch Pharmacol; 1992 May 29; 345(5):530-40. PubMed ID: 1356232
    [Abstract] [Full Text] [Related]

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