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593 related items for PubMed ID: 8570194

  • 1. RET activation by germline MEN2A and MEN2B mutations.
    Borrello MG, Smith DP, Pasini B, Bongarzone I, Greco A, Lorenzo MJ, Arighi E, Miranda C, Eng C, Alberti L.
    Oncogene; 1995 Dec 07; 11(11):2419-27. PubMed ID: 8570194
    [Abstract] [Full Text] [Related]

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  • 3. Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.
    Carlomagno F, Melillo RM, Visconti R, Salvatore G, De Vita G, Lupoli G, Yu Y, Jing S, Vecchio G, Fusco A, Santoro M.
    Endocrinology; 1998 Aug 07; 139(8):3613-9. PubMed ID: 9681515
    [Abstract] [Full Text] [Related]

  • 4. Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutations.
    Rossel M, Pasini A, Chappuis S, Geneste O, Fournier L, Schuffenecker I, Takahashi M, van Grunsven LA, Urdiales JL, Rudkin BB, Lenoir GM, Billaud M.
    Oncogene; 1997 Jan 23; 14(3):265-75. PubMed ID: 9018112
    [Abstract] [Full Text] [Related]

  • 5. Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B.
    Santoro M, Carlomagno F, Romano A, Bottaro DP, Dathan NA, Grieco M, Fusco A, Vecchio G, Matoskova B, Kraus MH.
    Science; 1995 Jan 20; 267(5196):381-3. PubMed ID: 7824936
    [Abstract] [Full Text] [Related]

  • 6. Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation.
    Iwashita T, Asai N, Murakami H, Matsuyama M, Takahashi M.
    Oncogene; 1996 Feb 01; 12(3):481-7. PubMed ID: 8637703
    [Abstract] [Full Text] [Related]

  • 7. [From gene to disease; from the RET gene to multiple endocrine neoplasia types 2A and 2B, sporadic and familial medullary thyroid carcinoma, Hirschsprung disease and papillary thyroid carcinoma].
    Hofstra RM, van der Luijt RB, Lips CJ.
    Ned Tijdschr Geneeskd; 2001 Nov 17; 145(46):2217-21. PubMed ID: 11757244
    [Abstract] [Full Text] [Related]

  • 8. A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins.
    Asai N, Murakami H, Iwashita T, Takahashi M.
    J Biol Chem; 1996 Jul 26; 271(30):17644-9. PubMed ID: 8663426
    [Abstract] [Full Text] [Related]

  • 9. A mutation in the RET proto-oncogene in Hirschsprung's disease affects the tyrosine kinase activity associated with multiple endocrine neoplasia type 2A and 2B.
    Cosma MP, Panariello L, Quadro L, Dathan NA, Fattoruso O, Colantuoni V.
    Biochem J; 1996 Mar 01; 314 ( Pt 2)(Pt 2):397-400. PubMed ID: 8670046
    [Abstract] [Full Text] [Related]

  • 10. Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation.
    Kawai K, Iwashita T, Murakami H, Hiraiwa N, Yoshiki A, Kusakabe M, Ono K, Iida K, Nakayama A, Takahashi M.
    Cancer Res; 2000 Sep 15; 60(18):5254-60. PubMed ID: 11016655
    [Abstract] [Full Text] [Related]

  • 11. Rudolf-Virchow-Preis 1995. The role of RET proto-oncogene mutation analysis in the diagnosis of multiple endocrine neoplasia type 2 (MEN 2) gene carriers and in the discrimination of sporadic and familial medullary thyroid carcinomas and pheochromocytomas.
    Komminoth P.
    Verh Dtsch Ges Pathol; 1995 Sep 15; 79():L-LV. PubMed ID: 8600671
    [Abstract] [Full Text] [Related]

  • 12. Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation.
    Bongarzone I, Vigano E, Alberti L, Borrello MG, Pasini B, Greco A, Mondellini P, Smith DP, Ponder BA, Romeo G, Pierotti MA.
    Oncogene; 1998 May 07; 16(18):2295-301. PubMed ID: 9620546
    [Abstract] [Full Text] [Related]

  • 13. RET proto-oncogene mutations are restricted to codons 634 and 918 in mainland Chinese families with MEN2A and MEN2B.
    Zhou Y, Zhao Y, Cui B, Gu L, Zhu S, Li J, Liu J, Yin M, Zhao T, Yin Z, Yu C, Chen C, Wang L, Xiao B, Hong J, Zhang Y, Tang Z, Wang S, Li X, Ning G.
    Clin Endocrinol (Oxf); 2007 Oct 07; 67(4):570-6. PubMed ID: 17573899
    [Abstract] [Full Text] [Related]

  • 14. Molecular mechanisms of development of multiple endocrine neoplasia 2 by RET mutations.
    Takahashi M, Asai N, Iwashita T, Murakami H, Ito S.
    J Intern Med; 1998 Jun 07; 243(6):509-13. PubMed ID: 9681851
    [Abstract] [Full Text] [Related]

  • 15. Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential.
    Cirafici AM, Salvatore G, De Vita G, Carlomagno F, Dathan NA, Visconti R, Melillo RM, Fusco A, Santoro M.
    Endocrinology; 1997 Apr 07; 138(4):1450-5. PubMed ID: 9075701
    [Abstract] [Full Text] [Related]

  • 16. Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations.
    Ohiwa M, Murakami H, Iwashita T, Asai N, Iwata Y, Imai T, Funahashi H, Takagi H, Takahashi M.
    Biochem Biophys Res Commun; 1997 Aug 28; 237(3):747-51. PubMed ID: 9299438
    [Abstract] [Full Text] [Related]

  • 17. RET proto-oncogene mutations in multiple endocrine neoplasia type 2 and medullary thyroid carcinoma.
    Marsh DJ, Mulligan LM, Eng C.
    Horm Res; 1997 Aug 28; 47(4-6):168-78. PubMed ID: 9167949
    [Abstract] [Full Text] [Related]

  • 18. The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype.
    Carlomagno F, Salvatore G, Cirafici AM, De Vita G, Melillo RM, de Franciscis V, Billaud M, Fusco A, Santoro M.
    Cancer Res; 1997 Feb 01; 57(3):391-5. PubMed ID: 9012462
    [Abstract] [Full Text] [Related]

  • 19. ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma.
    Vidal M, Wells S, Ryan A, Cagan R.
    Cancer Res; 2005 May 01; 65(9):3538-41. PubMed ID: 15867345
    [Abstract] [Full Text] [Related]

  • 20. Characterization of gene expression induced by RET with MEN2A or MEN2B mutation.
    Watanabe T, Ichihara M, Hashimoto M, Shimono K, Shimoyama Y, Nagasaka T, Murakumo Y, Murakami H, Sugiura H, Iwata H, Ishiguro N, Takahashi M.
    Am J Pathol; 2002 Jul 01; 161(1):249-56. PubMed ID: 12107109
    [Abstract] [Full Text] [Related]

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