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Journal Abstract Search

929 related items for PubMed ID: 8571133

  • 1. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance.
    Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM.
    Science; 1996 Feb 02; 271(5249):665-8. PubMed ID: 8571133
    [Abstract] [Full Text] [Related]

  • 2. Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase.
    Peraldi P, Hotamisligil GS, Buurman WA, White MF, Spiegelman BM.
    J Biol Chem; 1996 May 31; 271(22):13018-22. PubMed ID: 8662983
    [Abstract] [Full Text] [Related]

  • 3. Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
    Kanety H, Feinstein R, Papa MZ, Hemi R, Karasik A.
    J Biol Chem; 1995 Oct 06; 270(40):23780-4. PubMed ID: 7559552
    [Abstract] [Full Text] [Related]

  • 4. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
    Hotamisligil GS, Budavari A, Murray D, Spiegelman BM.
    J Clin Invest; 1994 Oct 06; 94(4):1543-9. PubMed ID: 7523453
    [Abstract] [Full Text] [Related]

  • 5. Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling.
    Rosenzweig T, Braiman L, Bak A, Alt A, Kuroki T, Sampson SR.
    Diabetes; 2002 Jun 06; 51(6):1921-30. PubMed ID: 12031982
    [Abstract] [Full Text] [Related]

  • 6. Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.
    Stephens JM, Lee J, Pilch PF.
    J Biol Chem; 1997 Jan 10; 272(2):971-6. PubMed ID: 8995390
    [Abstract] [Full Text] [Related]

  • 7. Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes.
    Valverde AM, Teruel T, Navarro P, Benito M, Lorenzo M.
    Endocrinology; 1998 Mar 10; 139(3):1229-38. PubMed ID: 9492058
    [Abstract] [Full Text] [Related]

  • 8. Acute selective glycogen synthase kinase-3 inhibition enhances insulin signaling in prediabetic insulin-resistant rat skeletal muscle.
    Dokken BB, Sloniger JA, Henriksen EJ.
    Am J Physiol Endocrinol Metab; 2005 Jun 10; 288(6):E1188-94. PubMed ID: 15671078
    [Abstract] [Full Text] [Related]

  • 9. Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase.
    Cheung AT, Wang J, Ree D, Kolls JK, Bryer-Ash M.
    Diabetes; 2000 May 10; 49(5):810-9. PubMed ID: 10905491
    [Abstract] [Full Text] [Related]

  • 10. Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.
    Lorenzo M, Fernández-Veledo S, Vila-Bedmar R, Garcia-Guerra L, De Alvaro C, Nieto-Vazquez I.
    J Anim Sci; 2008 Apr 10; 86(14 Suppl):E94-104. PubMed ID: 17940160
    [Abstract] [Full Text] [Related]

  • 11. An in vivo model for elucidation of the mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-alpha.
    Cheung AT, Ree D, Kolls JK, Fuselier J, Coy DH, Bryer-Ash M.
    Endocrinology; 1998 Dec 10; 139(12):4928-35. PubMed ID: 9832430
    [Abstract] [Full Text] [Related]

  • 12. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects.
    Rotter V, Nagaev I, Smith U.
    J Biol Chem; 2003 Nov 14; 278(46):45777-84. PubMed ID: 12952969
    [Abstract] [Full Text] [Related]

  • 13. Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes.
    Engelman JA, Berg AH, Lewis RY, Lisanti MP, Scherer PE.
    Mol Endocrinol; 2000 Oct 14; 14(10):1557-69. PubMed ID: 11043572
    [Abstract] [Full Text] [Related]

  • 14. Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling.
    Peraldi P, Xu M, Spiegelman BM.
    J Clin Invest; 1997 Oct 01; 100(7):1863-9. PubMed ID: 9312188
    [Abstract] [Full Text] [Related]

  • 15. Effect of tumor necrosis factor-alpha on insulin signal transduction in rat adipocytes: relation to PKCbeta and zeta translocation.
    Miura A, Ishizuka T, Kanoh Y, Ishizawa M, Itaya S, Kimura M, Kajita K, Yasuda K.
    Biochim Biophys Acta; 1999 Apr 01; 1449(3):227-38. PubMed ID: 10209302
    [Abstract] [Full Text] [Related]

  • 16. Tumor necrosis factor promotes phosphorylation and binding of insulin receptor substrate 1 to phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.
    Guo D, Donner DB.
    J Biol Chem; 1996 Jan 12; 271(2):615-8. PubMed ID: 8557661
    [Abstract] [Full Text] [Related]

  • 17. Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor.
    Liu LS, Spelleken M, Röhrig K, Hauner H, Eckel J.
    Diabetes; 1998 Apr 12; 47(4):515-22. PubMed ID: 9568681
    [Abstract] [Full Text] [Related]

  • 18. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.
    Jiang ZY, Lin YW, Clemont A, Feener EP, Hein KD, Igarashi M, Yamauchi T, White MF, King GL.
    J Clin Invest; 1999 Aug 12; 104(4):447-57. PubMed ID: 10449437
    [Abstract] [Full Text] [Related]

  • 19. Chronic tumor necrosis factor-alpha treatment causes insulin resistance via insulin receptor substrate-1 serine phosphorylation and suppressor of cytokine signaling-3 induction in 3T3-L1 adipocytes.
    Ishizuka K, Usui I, Kanatani Y, Bukhari A, He J, Fujisaka S, Yamazaki Y, Suzuki H, Hiratani K, Ishiki M, Iwata M, Urakaze M, Haruta T, Kobayashi M.
    Endocrinology; 2007 Jun 12; 148(6):2994-3003. PubMed ID: 17379643
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus.
    Skolnik EY, Marcusohn J.
    Cytokine Growth Factor Rev; 1996 Aug 12; 7(2):161-73. PubMed ID: 8899294
    [Abstract] [Full Text] [Related]

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