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Journal Abstract Search

469 related items for PubMed ID: 8573198

  • 1. 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes.
    Yamazaki H, Inoue K, Mimura M, Oda Y, Guengerich FP, Shimada T.
    Biochem Pharmacol; 1996 Feb 09; 51(3):313-9. PubMed ID: 8573198
    [Abstract] [Full Text] [Related]

  • 2. Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.
    Yamazaki H, Nakano M, Gillam EM, Bell LC, Guengerich FP, Shimada T.
    Biochem Pharmacol; 1996 Jul 26; 52(2):301-9. PubMed ID: 8694855
    [Abstract] [Full Text] [Related]

  • 3. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
    Kim KH, Isin EM, Yun CH, Kim DH, Guengerich FP.
    FEBS J; 2006 May 26; 273(10):2223-31. PubMed ID: 16649998
    [Abstract] [Full Text] [Related]

  • 4. Inhibitory monoclonal antibodies to human cytochrome P450 1A2: analysis of phenacetin O-deethylation in human liver.
    Yang TJ, Sai Y, Krausz KW, Gonzalez FJ, Gelboin HV.
    Pharmacogenetics; 1998 Oct 26; 8(5):375-82. PubMed ID: 9825829
    [Abstract] [Full Text] [Related]

  • 5. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H, Guo Z, Persmark M, Mimura M, Inoue K, Guengerich FP, Shimada T.
    Mol Pharmacol; 1994 Sep 26; 46(3):568-77. PubMed ID: 7935340
    [Abstract] [Full Text] [Related]

  • 6. Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.
    Duescher RJ, Elfarra AA.
    Arch Biochem Biophys; 1994 Jun 26; 311(2):342-9. PubMed ID: 8203896
    [Abstract] [Full Text] [Related]

  • 7. An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver.
    Sai Y, Yang TJ, Krausz KW, Gonzalez FJ, Gelboin HV.
    Pharmacogenetics; 1999 Apr 26; 9(2):229-37. PubMed ID: 10376770
    [Abstract] [Full Text] [Related]

  • 8. Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes.
    Rifkind AB, Lee C, Chang TK, Waxman DJ.
    Arch Biochem Biophys; 1995 Jul 10; 320(2):380-9. PubMed ID: 7625847
    [Abstract] [Full Text] [Related]

  • 9. Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes.
    Shimada T, Tsumura F, Yamazaki H.
    Drug Metab Dispos; 1999 Nov 10; 27(11):1274-80. PubMed ID: 10534312
    [Abstract] [Full Text] [Related]

  • 10. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H, Inui Y, Yun CH, Guengerich FP, Shimada T.
    Carcinogenesis; 1992 Oct 10; 13(10):1789-94. PubMed ID: 1423839
    [Abstract] [Full Text] [Related]

  • 11. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ, Smith TJ, Murphy SE, Wang MH, Lee J, Tynes RE, Koch P, Yang CS.
    Arch Biochem Biophys; 1996 Sep 01; 333(1):127-38. PubMed ID: 8806763
    [Abstract] [Full Text] [Related]

  • 12. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep 01; 24(9):948-54. PubMed ID: 8886603
    [Abstract] [Full Text] [Related]

  • 13. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes.
    Clarke SE, Baldwin SJ, Bloomer JC, Ayrton AD, Sozio RS, Chenery RJ.
    Chem Res Toxicol; 1994 Sep 01; 7(6):836-42. PubMed ID: 7696540
    [Abstract] [Full Text] [Related]

  • 14. Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics.
    Patten CJ, Thomas PE, Guy RL, Lee M, Gonzalez FJ, Guengerich FP, Yang CS.
    Chem Res Toxicol; 1993 Sep 01; 6(4):511-8. PubMed ID: 8374050
    [Abstract] [Full Text] [Related]

  • 15. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H, Shimada T.
    Xenobiotica; 1999 Mar 01; 29(3):231-41. PubMed ID: 10219964
    [Abstract] [Full Text] [Related]

  • 16. Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes.
    Yamazaki H, Tanaka M, Shimada T.
    J Chromatogr B Biomed Sci Appl; 1999 Jan 08; 721(1):13-9. PubMed ID: 10027632
    [Abstract] [Full Text] [Related]

  • 17. Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism.
    Yang TJ, Krausz KW, Sai Y, Gonzalez FJ, Gelboin HV.
    Drug Metab Dispos; 1999 Jan 08; 27(1):102-9. PubMed ID: 9884317
    [Abstract] [Full Text] [Related]

  • 18. A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin.
    Buters JT, Schiller CD, Chou RC.
    Biochem Pharmacol; 1993 Nov 02; 46(9):1577-84. PubMed ID: 8240414
    [Abstract] [Full Text] [Related]

  • 19. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane.
    Kharasch ED, Thummel KE.
    Anesthesiology; 1993 Oct 02; 79(4):795-807. PubMed ID: 8214760
    [Abstract] [Full Text] [Related]

  • 20. Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells.
    Patten CJ, Ishizaki H, Aoyama T, Lee M, Ning SM, Huang W, Gonzalez FJ, Yang CS.
    Arch Biochem Biophys; 1992 Nov 15; 299(1):163-71. PubMed ID: 1444447
    [Abstract] [Full Text] [Related]

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