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57 related items for PubMed ID: 8574139

  • 1. Uptake and distribution of 2',3'-dideoxyinosine and its derivatives in a human monocytoid cell line.
    Vázquez-Padua MA, Mayol N, López M.
    Cell Mol Biol (Noisy-le-grand); 1995; 41 Suppl 1():S113-9. PubMed ID: 8574139
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  • 2. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP, Nandy P, Avramis VI.
    In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
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  • 3. Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
    Kewn S, Hoggard PG, Henry-Mowatt JS, Veal GJ, Sales SD, Barry MG, Back DJ.
    AIDS Res Hum Retroviruses; 1999 Jun 10; 15(9):793-802. PubMed ID: 10381167
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  • 4. Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger.
    Meng Q, Su T, O'Neill JP, Walker VE.
    Environ Mol Mutagen; 2002 Jun 10; 39(4):282-95. PubMed ID: 12112380
    [Abstract] [Full Text] [Related]

  • 5. Cellular phosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key intermediate in the activation of the antiviral agent DDI, in human peripheral blood mononuclear cells.
    Robbins BL, Greenhaw J, Fridland A.
    Nucleosides Nucleotides Nucleic Acids; 2000 Jun 10; 19(1-2):405-13. PubMed ID: 10772723
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  • 6. Cellular pharmacology of 3'-azido-3'-deoxythymidine with evidence of incorporation into DNA of human bone marrow cells.
    Sommadossi JP, Carlisle R, Zhou Z.
    Mol Pharmacol; 1989 Jul 10; 36(1):9-14. PubMed ID: 2747633
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  • 7. Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
    Hartman NR, Ahluwalia GS, Cooney DA, Mitsuya H, Kageyama S, Fridland A, Broder S, Johns DG.
    Mol Pharmacol; 1991 Jul 10; 40(1):118-24. PubMed ID: 1677450
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  • 8. Effect of nucleoside analogs on neurite regeneration and mitochondrial DNA synthesis in PC-12 cells.
    Cui L, Locatelli L, Xie MY, Sommadossi JP.
    J Pharmacol Exp Ther; 1997 Mar 10; 280(3):1228-34. PubMed ID: 9067308
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  • 9. Determination of ddATP levels in human immunodeficiency virus-infected patients treated with dideoxyinosine.
    Le Saint C, Terreux R, Duval D, Durant J, Ettesse H, Dellamonica P, Guedj R, Vincent JP, Cupo A.
    Antimicrob Agents Chemother; 2004 Feb 10; 48(2):589-95. PubMed ID: 14742213
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  • 12. Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes.
    Pan-Zhou XR, Cretton-Scott E, Zhou XJ, Xie MY, Rahmani R, Schinazi RF, Duchin K, Sommadossi JP.
    Antimicrob Agents Chemother; 1997 Nov 10; 41(11):2502-10. PubMed ID: 9371357
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  • 13. Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine.
    Navé JF, Eschbach A, Wolff-Kugel D, Halazy S, Balzarini J.
    Biochem Pharmacol; 1994 Sep 15; 48(6):1105-12. PubMed ID: 7945403
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  • 15. Anomalous accumulation and decay of 2',3'-dideoxyadenosine-5'-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2',3'-dideoxyinosine.
    Ahluwalia G, Cooney DA, Hartman NR, Mitsuya H, Yarchoan R, Fridland A, Broder S, Johns DG.
    Drug Metab Dispos; 1993 Sep 15; 21(2):369-76. PubMed ID: 8097711
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  • 16. Intracellular activation and cytotoxicity of three different combinations of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine.
    Palmer S, Cox S.
    AIDS Res Hum Retroviruses; 1995 Oct 15; 11(10):1227-33. PubMed ID: 8573379
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  • 19. Role of altered metabolism in dideoxynucleoside pharmacokinetics. Studies of 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
    Singhal D, Morgan ME, Anderson BD.
    Drug Metab Dispos; 1996 Oct 15; 24(10):1155-61. PubMed ID: 8894519
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  • 20. Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment.
    Witt KL, Tice RR, Wolfe GW, Bishop JB.
    Environ Mol Mutagen; 2004 Oct 15; 44(4):321-8. PubMed ID: 15476197
    [Abstract] [Full Text] [Related]

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