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Journal Abstract Search

232 related items for PubMed ID: 8576122

  • 1. Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein.
    McConlogue L, Castellano F, deWit C, Schenk D, Maltese WA.
    J Biol Chem; 1996 Jan 19; 271(3):1343-8. PubMed ID: 8576122
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  • 2. The Ras-related GTP-binding protein, Rab1B, regulates early steps in exocytic transport and processing of beta-amyloid precursor protein.
    Dugan JM, deWit C, McConlogue L, Maltese WA.
    J Biol Chem; 1995 May 05; 270(18):10982-9. PubMed ID: 7738040
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  • 3. Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
    Thinakaran G, Teplow DB, Siman R, Greenberg B, Sisodia SS.
    J Biol Chem; 1996 Apr 19; 271(16):9390-7. PubMed ID: 8621605
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  • 4. Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.
    Lammich S, Kojro E, Postina R, Gilbert S, Pfeiffer R, Jasionowski M, Haass C, Fahrenholz F.
    Proc Natl Acad Sci U S A; 1999 Mar 30; 96(7):3922-7. PubMed ID: 10097139
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  • 5. Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism.
    Tomita S, Kirino Y, Suzuki T.
    J Biol Chem; 1998 Mar 13; 273(11):6277-84. PubMed ID: 9497354
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  • 6. The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells.
    Kuentzel SL, Ali SM, Altman RA, Greenberg BD, Raub TJ.
    Biochem J; 1993 Oct 15; 295 ( Pt 2)(Pt 2):367-78. PubMed ID: 8240235
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  • 9. Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1.
    Chang Y, Tesco G, Jeong WJ, Lindsley L, Eckman EA, Eckman CB, Tanzi RE, Guénette SY.
    J Biol Chem; 2003 Dec 19; 278(51):51100-7. PubMed ID: 14527950
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  • 10. beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations.
    McPhie DL, Golde T, Eckman CB, Yager D, Brant JB, Neve RL.
    Brain Res Mol Brain Res; 2001 Dec 16; 97(1):103-13. PubMed ID: 11744168
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  • 11. Inhibition of receptor-mediated endocytosis demonstrates generation of amyloid beta-protein at the cell surface.
    Chyung JH, Selkoe DJ.
    J Biol Chem; 2003 Dec 19; 278(51):51035-43. PubMed ID: 14525989
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  • 12. The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway.
    Haass C, Lemere CA, Capell A, Citron M, Seubert P, Schenk D, Lannfelt L, Selkoe DJ.
    Nat Med; 1995 Dec 19; 1(12):1291-6. PubMed ID: 7489411
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  • 13. The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons.
    Tan JZA, Gleeson PA.
    J Biol Chem; 2019 Feb 01; 294(5):1618-1631. PubMed ID: 30545942
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  • 14. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network.
    Skovronsky DM, Moore DB, Milla ME, Doms RW, Lee VM.
    J Biol Chem; 2000 Jan 28; 275(4):2568-75. PubMed ID: 10644715
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  • 15. Spatial-Temporal Mapping Reveals the Golgi as the Major Processing Site for the Pathogenic Swedish APP Mutation: Familial APP Mutant Shifts the Major APP Processing Site.
    Wang J, Gleeson PA, Fourriere L.
    Traffic; 2024 Mar 28; 25(3):e12932. PubMed ID: 38528836
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  • 17. Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein.
    Carey RM, Balcz BA, Lopez-Coviella I, Slack BE.
    BMC Cell Biol; 2005 Aug 11; 6():30. PubMed ID: 16095541
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  • 18. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein.
    Bodovitz S, Klein WL.
    J Biol Chem; 1996 Feb 23; 271(8):4436-40. PubMed ID: 8626795
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