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115 related items for PubMed ID: 8585758

  • 1. In vitro anti-HIV-1 activity of HIV protease inhibitor KNI-272 in resting and activated cells: implications for its combined use with AZT or ddI.
    Chokekijchai S, Shirasaka T, Weinstein JN, Mitsuya H.
    Antiviral Res; 1995 Sep; 28(1):25-38. PubMed ID: 8585758
    [Abstract] [Full Text] [Related]

  • 2. In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.
    Kageyama S, Mimoto T, Murakawa Y, Nomizu M, Ford H, Shirasaka T, Gulnik S, Erickson J, Takada K, Hayashi H.
    Antimicrob Agents Chemother; 1993 Apr; 37(4):810-7. PubMed ID: 8494379
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  • 3. Kynostatin (KNI)-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine.
    Mimoto T, Imai J, Kisanuki S, Enomoto H, Hattori N, Akaji K, Kiso Y.
    Chem Pharm Bull (Tokyo); 1992 Aug; 40(8):2251-3. PubMed ID: 1423795
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  • 4. Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.
    Gao WY, Shirasaka T, Johns DG, Broder S, Mitsuya H.
    J Clin Invest; 1993 May; 91(5):2326-33. PubMed ID: 8387546
    [Abstract] [Full Text] [Related]

  • 5. Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere.
    Kiso Y.
    Biopolymers; 1996 May; 40(2):235-44. PubMed ID: 8785365
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  • 6. In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations.
    Kageyama S, Weinstein JN, Shirasaka T, Kempf DJ, Norbeck DW, Plattner JJ, Erickson J, Mitsuya H.
    Antimicrob Agents Chemother; 1992 May; 36(5):926-33. PubMed ID: 1510415
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  • 10. HIV-1 acquires resistance to two classes of antiviral drugs through homologous recombination.
    Yusa K, Kavlick MF, Kosalaraksa P, Mitsuya H.
    Antiviral Res; 1997 Dec; 36(3):179-89. PubMed ID: 9477118
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  • 11. Protein binding of human immunodeficiency virus protease inhibitor KNI-272 and alteration of its in vitro antiretroviral activity in the presence of high concentrations of proteins.
    Kageyama S, Anderson BD, Hoesterey BL, Hayashi H, Kiso Y, Flora KP, Mitsuya H.
    Antimicrob Agents Chemother; 1994 May; 38(5):1107-11. PubMed ID: 8067746
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  • 12. Ganciclovir antagonizes the anti-human immunodeficiency virus type 1 activity of zidovudine and didanosine in vitro.
    Medina DJ, Hsiung GD, Mellors JW.
    Antimicrob Agents Chemother; 1992 May; 36(5):1127-30. PubMed ID: 1510405
    [Abstract] [Full Text] [Related]

  • 13. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP, Nandy P, Avramis VI.
    In Vivo; 2000 May; 14(3):377-88. PubMed ID: 10904870
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  • 14. Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere.
    Mimoto T, Hattori N, Takaku H, Kisanuki S, Fukazawa T, Terashima K, Kato R, Nojima S, Misawa S, Ueno T, Imai J, Enomoto H, Tanaka S, Sakikawa H, Shintani M, Hayashi H, Kiso Y.
    Chem Pharm Bull (Tokyo); 2000 Sep; 48(9):1310-26. PubMed ID: 10993230
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  • 15. Synergistic drug interactions of an HIV-1 protease inhibitor with AZT in different in vitro models of HIV-1 infection.
    Lambert DM, Bartus H, Fernandez AV, Bratby-Anders C, Leary JJ, Dreyer GB, Metcalf BW, Petteway SR.
    Antiviral Res; 1993 Aug; 21(4):327-42. PubMed ID: 7692816
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  • 16. Loss of synergistic response to combinations containing AZT in AZT-resistant HIV-1.
    Cox SW, Albert J, Wahlberg J, Uhlén M, Wahren B.
    AIDS Res Hum Retroviruses; 1992 Jul; 8(7):1229-34. PubMed ID: 1520536
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  • 17. Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
    Taylor DL, Ahmed PS, Tyms AS, Wood LJ, Kelly LA, Chambers P, Clarke J, Bedard J, Bowlin TL, Rando RF.
    Antivir Chem Chemother; 2000 Jul; 11(4):291-301. PubMed ID: 10950391
    [Abstract] [Full Text] [Related]

  • 18. Comparison of the sensitivities of primary isolates of HIV type 2 and HIV type 1 to antiviral drugs and drug combinations.
    Cox SW, Apéria K, Albert J, Wahren B.
    AIDS Res Hum Retroviruses; 1994 Dec; 10(12):1725-9. PubMed ID: 7888232
    [Abstract] [Full Text] [Related]

  • 19. Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine.
    Baldwin ET, Bhat TN, Gulnik S, Liu B, Topol IA, Kiso Y, Mimoto T, Mitsuya H, Erickson JW.
    Structure; 1995 Jun 15; 3(6):581-90. PubMed ID: 8590019
    [Abstract] [Full Text] [Related]

  • 20. Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells.
    Dornsife RE, St Clair MH, Huang AT, Panella TJ, Koszalka GW, Burns CL, Averett DR.
    Antimicrob Agents Chemother; 1991 Feb 15; 35(2):322-8. PubMed ID: 1708977
    [Abstract] [Full Text] [Related]

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