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246 related items for PubMed ID: 8596487

  • 1. Somatostatin and insulin secretion due to common mechanisms by a new hypoglycemic agent, A-4166, in perfused rat pancreas.
    Fujitani S, Ikenoue T, Akiyoshi M, Maki T, Yada T.
    Metabolism; 1996 Feb; 45(2):184-9. PubMed ID: 8596487
    [Abstract] [Full Text] [Related]

  • 2. A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx.
    Fujitani S, Yada T.
    Endocrinology; 1994 Mar; 134(3):1395-400. PubMed ID: 8119179
    [Abstract] [Full Text] [Related]

  • 3. Insulin secretion from isolated rat islets induced by the novel hypoglycemic agent A-4166, a derivative of D-phenylalanine.
    Tsukuda K, Sakurada M, Niki I, Oka Y, Kikuchi M.
    Horm Metab Res; 1998 Jan; 30(1):42-9. PubMed ID: 9503038
    [Abstract] [Full Text] [Related]

  • 4. Effects of D-phenylalanine-derivative hypoglycemic agent A-4166 on pancreatic alpha- and beta-cells: comparative study with glibenclamide.
    Hirose H, Maruyama H, Seto Y, Ito K, Fujita T, Dan K, Kanda N, Saruta T, Kato R.
    Pharmacology; 1995 Mar; 50(3):175-81. PubMed ID: 7746834
    [Abstract] [Full Text] [Related]

  • 5. Effects of N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine (A-4166) on insulin and glucagon secretion in isolated perfused rat pancreas.
    Hirose H, Maruyama H, Ito K, Seto Y, Kido K, Koyama K, Dan K, Saruta T, Kato R.
    Pharmacology; 1994 Apr; 48(4):205-10. PubMed ID: 8177906
    [Abstract] [Full Text] [Related]

  • 6. Possibility of ideal blood glucose control by a new oral hypoglycemic agent, N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine (A-4166), and its stimulatory effect on insulin secretion in animals.
    Sato Y, Nishikawa M, Shinkai H, Sukegawa E.
    Diabetes Res Clin Pract; 1991 Apr; 12(1):53-9. PubMed ID: 1906797
    [Abstract] [Full Text] [Related]

  • 7. Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1.
    de Heer J, Holst JJ.
    Diabetes; 2007 Feb; 56(2):438-43. PubMed ID: 17259389
    [Abstract] [Full Text] [Related]

  • 8. A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic beta-cells.
    Akiyoshi M, Kakei M, Nakazaki M, Tanaka H.
    Am J Physiol; 1995 Feb; 268(2 Pt 1):E185-93. PubMed ID: 7864093
    [Abstract] [Full Text] [Related]

  • 9. Effect of a non-sulphonylurea hypoglycaemic agent, KAD-1229 on hormone secretion in the isolated perfused pancreas of the rat.
    Kinukawa M, Ohnota H, Ajisawa Y.
    Br J Pharmacol; 1996 Apr; 117(8):1702-6. PubMed ID: 8732279
    [Abstract] [Full Text] [Related]

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  • 11. Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide.
    Ball AJ, Flatt PR, McClenaghan NH.
    Biochem Pharmacol; 2005 Jan 01; 69(1):59-63. PubMed ID: 15588714
    [Abstract] [Full Text] [Related]

  • 12. Stimulation of insulin and somatostatin release by two meglitinide analogs.
    Leclercq-Meyer V, Ladrière L, Fuhlendorff J, Malaisse WJ.
    Endocrine; 1997 Dec 01; 7(3):311-7. PubMed ID: 9657067
    [Abstract] [Full Text] [Related]

  • 13. The ability of a new hypoglycaemic agent, A-4166, compared to sulphonylureas, to increase cytosolic Ca2+ in pancreatic beta-cells under metabolic inhibition.
    Fujitani S, Okazaki K, Yada T.
    Br J Pharmacol; 1997 Apr 01; 120(7):1191-8. PubMed ID: 9105692
    [Abstract] [Full Text] [Related]

  • 14. Effect of tolbutamide on insulin, glucagon, and somatostatin release from the diabetic rat pancreas with special reference to glucose concentration.
    Kadowaki S, Taminato T, Chiba T, Nozawa M, Fujita T, Norman AW.
    Endocrinology; 1983 Jun 01; 112(6):2187-92. PubMed ID: 6133743
    [Abstract] [Full Text] [Related]

  • 15. Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells.
    Cheng-Xue R, Gómez-Ruiz A, Antoine N, Noël LA, Chae HY, Ravier MA, Chimienti F, Schuit FC, Gilon P.
    Diabetes; 2013 May 01; 62(5):1612-22. PubMed ID: 23382449
    [Abstract] [Full Text] [Related]

  • 16. Interaction of nateglinide with K(ATP) channel in beta-cells underlies its unique insulinotropic action.
    Hu S.
    Eur J Pharmacol; 2002 May 03; 442(1-2):163-71. PubMed ID: 12020694
    [Abstract] [Full Text] [Related]

  • 17. Difference in calcium dependency of insulin, glucagon and somatostatin secretion in response to glibenclamide in perfused rat pancreas.
    Efendić S, Grill V, Nylén A, Ostensson CG.
    Diabetologia; 1982 Jun 03; 22(6):475-9. PubMed ID: 6125449
    [Abstract] [Full Text] [Related]

  • 18. The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide.
    Sunaga Y, Gonoi T, Shibasaki T, Ichikawa K, Kusama H, Yano H, Seino S.
    Eur J Pharmacol; 2001 Nov 09; 431(1):119-25. PubMed ID: 11716850
    [Abstract] [Full Text] [Related]

  • 19. Actions of glucagon-like peptide-1 on KATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide.
    McClenaghan NH, Flatt PR, Ball AJ.
    J Endocrinol; 2006 Sep 09; 190(3):889-96. PubMed ID: 17003289
    [Abstract] [Full Text] [Related]

  • 20. Ay-4166 increases the sensitivity of insulin secretion to glucose in isolated perfused rat pancreas.
    Morimoto S, Mokuda O, Sakamoto Y.
    Horm Metab Res; 1998 Feb 09; 30(2):77-9. PubMed ID: 9543688
    [Abstract] [Full Text] [Related]

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