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Journal Abstract Search

381 related items for PubMed ID: 8596638

  • 1.
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  • 2. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
    Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D.
    Nature; 1993 May 06; 363(6424):83-5. PubMed ID: 8479540
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  • 3. Identification of epidermal growth factor receptor- Grb2-associated binder-1-SHP-2 complex formation and its functional loss during neoplastic cell progression.
    Kameda H, Risinger JI, Han BB, Baek SJ, Barrett JC, Glasgow WC, Eling TE.
    Cell Growth Differ; 2001 Jun 06; 12(6):307-18. PubMed ID: 11432805
    [Abstract] [Full Text] [Related]

  • 4. The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
    Lewitzky M, Kardinal C, Gehring NH, Schmidt EK, Konkol B, Eulitz M, Birchmeier W, Schaeper U, Feller SM.
    Oncogene; 2001 Mar 01; 20(9):1052-62. PubMed ID: 11314042
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  • 7. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
    Zhang T, Ma J, Cao X.
    Biochem J; 2003 Dec 01; 376(Pt 2):457-64. PubMed ID: 14498832
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  • 8. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway.
    Nakamura T, Sanokawa R, Sasaki Y, Ayusawa D, Oishi M, Mori N.
    Oncogene; 1996 Sep 19; 13(6):1111-21. PubMed ID: 8808684
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  • 9. Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.
    Najib S, Sánchez-Margalet V.
    J Cell Biochem; 2002 Sep 19; 86(1):99-106. PubMed ID: 12112020
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  • 10. p21Ras activation by the guanine nucleotide exchange factor Sos, requires the Sos/Grb2 interaction and a second ligand-dependent signal involving the Sos N-terminus.
    Byrne JL, Paterson HF, Marshall CJ.
    Oncogene; 1996 Nov 21; 13(10):2055-65. PubMed ID: 8950972
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  • 12. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
    Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D.
    Nature; 1993 May 06; 363(6424):88-92. PubMed ID: 8386805
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  • 13. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
    Ahmed Z, Pillay TS.
    Biochem J; 2003 Apr 15; 371(Pt 2):405-12. PubMed ID: 12521378
    [Abstract] [Full Text] [Related]

  • 14. Dynamin II associates with Grb2 SH3 domain in Ras transformed NIH3T3 cells.
    Yoon SY, Koh WS, Lee MK, Park YM, Han MY.
    Biochem Biophys Res Commun; 1997 May 29; 234(3):539-43. PubMed ID: 9175747
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  • 16. Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.
    Boerner JL, Danielsen AJ, Lovejoy CA, Wang Z, Juneja SC, Faupel-Badger JM, Darce JR, Maihle NJ.
    Oncogene; 2003 Oct 02; 22(43):6679-89. PubMed ID: 14555981
    [Abstract] [Full Text] [Related]

  • 17. Involvement of the actin network in insulin signalling.
    Tsakiridis T, Wang Q, Taha C, Grinstein S, Downey G, Klip A.
    Soc Gen Physiol Ser; 1997 Oct 02; 52():257-71. PubMed ID: 9210235
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  • 18. Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc.
    Kranenburg O, Verlaan I, Hordijk PL, Moolenaar WH.
    EMBO J; 1997 Jun 02; 16(11):3097-105. PubMed ID: 9214627
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  • 19. The RIalpha subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor.
    Tortora G, Damiano V, Bianco C, Baldassarre G, Bianco AR, Lanfrancone L, Pelicci PG, Ciardiello F.
    Oncogene; 1997 Feb 27; 14(8):923-8. PubMed ID: 9050991
    [Abstract] [Full Text] [Related]

  • 20. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P, Liu WQ, Broutin I, Charbonnier F, Latreille MT, Vidal M, Roques B, Garbay C, Ducruix A.
    J Mol Biol; 2002 Feb 01; 315(5):1167-77. PubMed ID: 11827484
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