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Journal Abstract Search

205 related items for PubMed ID: 8602351

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  • 2. Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression.
    McKay RA, Miraglia LJ, Cummins LL, Owens SR, Sasmor H, Dean NM.
    J Biol Chem; 1999 Jan 15; 274(3):1715-22. PubMed ID: 9880552
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  • 4. Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides.
    Dean NM, McKay R.
    Proc Natl Acad Sci U S A; 1994 Nov 22; 91(24):11762-6. PubMed ID: 7972137
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  • 5. Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras.
    Monia BP, Johnston JF, Sasmor H, Cummins LL.
    J Biol Chem; 1996 Jun 14; 271(24):14533-40. PubMed ID: 8662854
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  • 6. Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-alpha (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligodeoxynucleotides: relationship to the decreased viability of T24 bladder and PC3 prostate cancer cells.
    Benimetskaya L, Miller P, Benimetsky S, Maciaszek A, Guga P, Beaucage SL, Wilk A, Grajkowski A, Halperin AL, Stein CA.
    Mol Pharmacol; 2001 Dec 14; 60(6):1296-307. PubMed ID: 11723237
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  • 7. Pharmacokinetic properties of several novel oligonucleotide analogs in mice.
    Crooke ST, Graham MJ, Zuckerman JE, Brooks D, Conklin BS, Cummins LL, Greig MJ, Guinosso CJ, Kornbrust D, Manoharan M, Sasmor HM, Schleich T, Tivel KL, Griffey RH.
    J Pharmacol Exp Ther; 1996 May 14; 277(2):923-37. PubMed ID: 8627575
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  • 9. Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-alpha.
    Dennis JU, Dean NM, Bennett CF, Griffith JW, Lang CM, Welch DR.
    Cancer Lett; 1998 Jun 05; 128(1):65-70. PubMed ID: 9652794
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  • 13. Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide.
    Yazaki T, Ahmad S, Chahlavi A, Zylber-Katz E, Dean NM, Rabkin SD, Martuza RL, Glazer RI.
    Mol Pharmacol; 1996 Aug 05; 50(2):236-42. PubMed ID: 8700129
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  • 16. Inhibition of protein kinase C-alpha expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters.
    Dean NM, McKay R, Condon TP, Bennett CF.
    J Biol Chem; 1994 Jun 10; 269(23):16416-24. PubMed ID: 7911467
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  • 17. Design of antisense oligonucleotides stabilized by locked nucleic acids.
    Kurreck J, Wyszko E, Gillen C, Erdmann VA.
    Nucleic Acids Res; 2002 May 01; 30(9):1911-8. PubMed ID: 11972327
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  • 18. Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets.
    Kawasaki AM, Casper MD, Freier SM, Lesnik EA, Zounes MC, Cummins LL, Gonzalez C, Cook PD.
    J Med Chem; 1993 Apr 02; 36(7):831-41. PubMed ID: 8464037
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  • 19. Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer.
    Yuen AR, Halsey J, Fisher GA, Holmlund JT, Geary RS, Kwoh TJ, Dorr A, Sikic BI.
    Clin Cancer Res; 1999 Nov 02; 5(11):3357-63. PubMed ID: 10589745
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  • 20. In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells.
    Bijsterbosch MK, Manoharan M, Rump ET, De Vrueh RL, van Veghel R, Tivel KL, Biessen EA, Bennett CF, Cook PD, van Berkel TJ.
    Nucleic Acids Res; 1997 Aug 15; 25(16):3290-6. PubMed ID: 9241243
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