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149 related items for PubMed ID: 8603484

  • 1. Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Hirose M, Hasegawa R, Kimura J, Akagi K, Yoshida Y, Tanaka H, Miki T, Satoh T, Wakabayashi K, Ito N.
    Carcinogenesis; 1995 Dec; 16(12):3049-55. PubMed ID: 8603484
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  • 2. Prevention by antioxidants of heterocyclic amine-induced carcinogenesis in a rat medium-term liver bioassay: results of extended and combination treatment experiments.
    Hirose M, Futakuchi M, Tanaka H, Orita SI, Ito T, Miki T, Shirai T.
    Eur J Cancer Prev; 1998 Feb; 7(1):61-7. PubMed ID: 9511852
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  • 3. Phenolics: blocking agents for heterocyclic amine-induced carcinogenesis.
    Hirose M, Takahashi S, Ogawa K, Futakuchi M, Shirai T.
    Food Chem Toxicol; 1999 Feb; 37(9-10):985-92. PubMed ID: 10541455
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  • 4. Strong inhibition of 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone.
    Hirose M, Akagi K, Hasegawa R, Satoh T, Nihro Y, Miki T, Sugimura T, Ito N.
    Jpn J Cancer Res; 1993 May; 84(5):481-4. PubMed ID: 8320163
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  • 5. Strong anti-mutagenic activity of the novel lipophilic antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone against heterocyclic amine-induced mutagenesis in the Ames assay and its effect on metabolic activation of 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole (Glu-p-1).
    Hirose M, Iwata S, Ito E, Nihro Y, Takahashi S, Mizoguchi Y, Miki T, Satoh T, Ito N, Shirai T.
    Carcinogenesis; 1995 Sep; 16(9):2227-32. PubMed ID: 7554080
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  • 6. Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.
    Hirose M, Takahashi S, Ogawa K, Futakuchi M, Shirai T, Shibutani M, Uneyama C, Toyoda K, Iwata H.
    Cancer Lett; 1999 Sep 01; 143(2):173-8. PubMed ID: 10503899
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  • 9. Inhibition of DMBA-initiated rat mammary tumour development by 1-O-hexyl-2,3,5-trimethylhydroquinone, phenylethyl isothiocyanate, and novel synthetic ascorbic acid derivatives.
    Futakuchi M, Hirose M, Miki T, Tanaka H, Ozaki M, Shirai T.
    Eur J Cancer Prev; 1998 Apr 01; 7(2):153-9. PubMed ID: 9818778
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  • 10. Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesis model.
    Kawabe M, Futakuchi M, Tamano S, Shirai T, Hirose M.
    Food Chem Toxicol; 2008 Aug 01; 46(8):2758-63. PubMed ID: 18547703
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  • 11. Stage and organ dependent effects of 1-O-hexyl-2,3,5-trimethylhydroquinone, ascorbic acid derivatives, n-heptadecane-8-10-dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model.
    Ogawa K, Futakuchi M, Hirose M, Boonyaphiphat P, Mizoguchi Y, Miki T, Shirai T.
    Int J Cancer; 1998 Jun 10; 76(6):851-6. PubMed ID: 9626352
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  • 12. Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats.
    Hirose M, Nishikawa A, Shibutani M, Imai T, Shirai T.
    Environ Mol Mutagen; 2002 Jun 10; 39(2-3):271-8. PubMed ID: 11921198
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  • 13. Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.
    Fujita K, Ohnishi T, Sekine K, Iigo M, Tsuda H.
    Jpn J Cancer Res; 2002 Jun 10; 93(6):616-25. PubMed ID: 12079509
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  • 15. Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses.
    Ito N, Hasegawa R, Shirai T, Fukushima S, Hakoi K, Takaba K, Iwasaki S, Wakabayashi K, Nagao M, Sugimura T.
    Carcinogenesis; 1991 May 10; 12(5):767-72. PubMed ID: 2029739
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  • 17. Synergistic enhancement of hepatic foci development by combined treatment of rats with 10 heterocyclic amines at low doses.
    Hasegawa R, Miyata E, Futakuchi M, Hagiwara A, Nagao M, Sugimura T, Ito N.
    Carcinogenesis; 1994 May 10; 15(5):1037-41. PubMed ID: 8200065
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  • 18. Dose dependence of 1-O-hexyl-2,3,5-trimethylhydroquinone promotion of forestomach carcinogenesis in rats pretreated with N-ethylnitrosourethane.
    Mizoguchi Y, Hirose M, Yamaguchi T, Boonyaphiphat P, Miki T, Shirai T.
    Jpn J Cancer Res; 1998 May 10; 89(5):475-80. PubMed ID: 9685849
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  • 20. Analysis of synergism in hepatocarcinogenesis based on preneoplastic foci induction by 10 heterocyclic amines in the rat.
    Hasegawa R, Yoshimura I, Imaida K, Ito N, Shirai T.
    Jpn J Cancer Res; 1996 Nov 10; 87(11):1125-33. PubMed ID: 9045941
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