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168 related items for PubMed ID: 8605148
41. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases. Qasim MA, Lu SM, Ding J, Bateman KS, James MN, Anderson S, Song J, Markley JL, Ganz PJ, Saunders CW, Laskowski M. Biochemistry; 1999 Jun 01; 38(22):7142-50. PubMed ID: 10353824 [Abstract] [Full Text] [Related]
42. X-ray and neutron protein crystallographic analysis of the trypsin-BPTI complex. Kawamura K, Yamada T, Kurihara K, Tamada T, Kuroki R, Tanaka I, Takahashi H, Niimura N. Acta Crystallogr D Biol Crystallogr; 2011 Feb 01; 67(Pt 2):140-8. PubMed ID: 21245536 [Abstract] [Full Text] [Related]
43. Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases. Oleksyszyn J, Boduszek B, Kam CM, Powers JC. J Med Chem; 1994 Jan 21; 37(2):226-31. PubMed ID: 8295209 [Abstract] [Full Text] [Related]
44. Comparative binding energy analysis considering multiple receptors: a step toward 3D-QSAR models for multiple targets. Murcia M, Morreale A, Ortiz AR. J Med Chem; 2006 Oct 19; 49(21):6241-53. PubMed ID: 17034130 [Abstract] [Full Text] [Related]
45. A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions. Olsen JA, Banner DW, Seiler P, Obst Sander U, D'Arcy A, Stihle M, Müller K, Diederich F. Angew Chem Int Ed Engl; 2003 Jun 06; 42(22):2507-11. PubMed ID: 12800172 [No Abstract] [Full Text] [Related]
46. Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Stoll VS, Eger BT, Hynes RC, Martichonok V, Jones JB, Pai EF. Biochemistry; 1998 Jan 13; 37(2):451-62. PubMed ID: 9425066 [Abstract] [Full Text] [Related]
47. Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes. Bone R, Lu T, Illig CR, Soll RM, Spurlino JC. J Med Chem; 1998 Jun 04; 41(12):2068-75. PubMed ID: 9622548 [Abstract] [Full Text] [Related]
48. Structure-based understanding of ligand affinity using human thrombin as a model system. Nienaber VL, Mersinger LJ, Kettner CA. Biochemistry; 1996 Jul 30; 35(30):9690-9. PubMed ID: 8703940 [Abstract] [Full Text] [Related]
49. Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis. Fodor K, Harmat V, Neutze R, Szilágyi L, Gráf L, Katona G. Biochemistry; 2006 Feb 21; 45(7):2114-21. PubMed ID: 16475800 [Abstract] [Full Text] [Related]
50. Inhibition of bovine beta-trypsin, human alpha-thrombin and porcine pancreatic beta-kallikrein-B by 4',6-diamidino-2-phenylindole, 6-amidinoindole and benzamidine: a comparative thermodynamic and X-ray structural study. Casale E, Collyer C, Ascenzi P, Balliano G, Milla P, Viola F, Fasano M, Menegatti E, Bolognesi M. Biophys Chem; 1995 Mar 21; 54(1):75-81. PubMed ID: 7703351 [Abstract] [Full Text] [Related]
51. Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors. Katz BA, Elrod K, Verner E, Mackman RL, Luong C, Shrader WD, Sendzik M, Spencer JR, Sprengeler PA, Kolesnikov A, Tai VW, Hui HC, Breitenbucher JG, Allen D, Janc JW. J Mol Biol; 2003 May 23; 329(1):93-120. PubMed ID: 12742021 [Abstract] [Full Text] [Related]
53. Structure of human pro-chymase: a model for the activating transition of granule-associated proteases. Reiling KK, Krucinski J, Miercke LJ, Raymond WW, Caughey GH, Stroud RM. Biochemistry; 2003 Mar 11; 42(9):2616-24. PubMed ID: 12614156 [Abstract] [Full Text] [Related]
57. A crystallographic re-investigation into the structure of Streptomyces griseus proteinase A reveals an acyl-enzyme intermediate. Blanchard H, James MN. J Mol Biol; 1994 Aug 26; 241(4):574-87. PubMed ID: 8057380 [Abstract] [Full Text] [Related]
59. Design and X-ray crystal structures of human thrombin with synthetic cyanopeptide-analogues. Radau G, Fokkens J. Pharmazie; 2007 Feb 26; 62(2):83-8. PubMed ID: 17341023 [Abstract] [Full Text] [Related]