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258 related items for PubMed ID: 8609216

  • 1. Immunity to the G1 globular domain of the cartilage proteoglycan aggrecan can induce inflammatory erosive polyarthritis and spondylitis in BALB/c mice but immunity to G1 is inhibited by covalently bound keratan sulfate in vitro and in vivo.
    Leroux JY, Guerassimov A, Cartman A, Delaunay N, Webber C, Rosenberg LC, Banerjee S, Poole AR.
    J Clin Invest; 1996 Feb 01; 97(3):621-32. PubMed ID: 8609216
    [Abstract] [Full Text] [Related]

  • 2. Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice. Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes.
    Zhang Y, Guerassimov A, Leroux JY, Cartman A, Webber C, Lalic R, de Miguel E, Rosenberg LC, Poole AR.
    J Clin Invest; 1998 Apr 15; 101(8):1678-86. PubMed ID: 9541498
    [Abstract] [Full Text] [Related]

  • 3. Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate.
    Guerassimov A, Zhang Y, Banerjee S, Cartman A, Leroux JY, Rosenberg LC, Esdaile J, Fitzcharles MA, Poole AR.
    Arthritis Rheum; 1998 Jun 15; 41(6):1019-25. PubMed ID: 9627011
    [Abstract] [Full Text] [Related]

  • 4. Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation.
    Glant TT, Buzás EI, Finnegan A, Negroiu G, Cs-Szabó G, Mikecz K.
    J Immunol; 1998 Apr 15; 160(8):3812-9. PubMed ID: 9558085
    [Abstract] [Full Text] [Related]

  • 5. Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan.
    Hanyecz A, Bárdos T, Berlo SE, Buzás E, Nesterovitch AB, Mikecz K, Glant TT.
    Arthritis Rheum; 2003 Oct 15; 48(10):2959-73. PubMed ID: 14558103
    [Abstract] [Full Text] [Related]

  • 6. Immune responses to cartilage link protein and the G1 domain of proteoglycan aggrecan in patients with osteoarthritis.
    Guerassimov A, Zhang Y, Cartman A, Rosenberg LC, Esdaile J, Fitzcharles MA, Poole AR.
    Arthritis Rheum; 1999 Mar 15; 42(3):527-33. PubMed ID: 10088776
    [Abstract] [Full Text] [Related]

  • 7. Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis.
    Glant TT, Fülöp C, Cs-Szabó G, Buzás E, Ragasa D, Mikecz K.
    Scand J Rheumatol Suppl; 1995 Mar 15; 101():43-9. PubMed ID: 7538228
    [Abstract] [Full Text] [Related]

  • 8. Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.
    Glant TT, Cs-Szabó G, Nagase H, Jacobs JJ, Mikecz K.
    Arthritis Rheum; 1998 Jun 15; 41(6):1007-18. PubMed ID: 9627010
    [Abstract] [Full Text] [Related]

  • 9. Experimental immunity to the G1 domain of the proteoglycan versican induces spondylitis and sacroiliitis, of a kind seen in human spondylarthropathies.
    Shi S, Ciurli C, Cartman A, Pidoux I, Poole AR, Zhang Y.
    Arthritis Rheum; 2003 Oct 15; 48(10):2903-15. PubMed ID: 14558097
    [Abstract] [Full Text] [Related]

  • 10. Monoclonal antibodies directed against epitopes within the core protein structure of the large aggregating proteoglycan (aggrecan) from the swarm rat chondrosarcoma.
    Calabro A, Hascall VC, Caterson B.
    Arch Biochem Biophys; 1992 Nov 01; 298(2):349-60. PubMed ID: 1384430
    [Abstract] [Full Text] [Related]

  • 11. A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice.
    Buzás EI, Brennan FR, Mikecz K, Garzó M, Negroiu G, Holló K, Cs-Szabó G, Pintye E, Glant TT.
    J Immunol; 1995 Sep 01; 155(5):2679-87. PubMed ID: 7544381
    [Abstract] [Full Text] [Related]

  • 12. Characterization of proteoglycan-reactive T cell lines and hybridomas from mice with proteoglycan-induced arthritis.
    Leroux JY, Poole AR, Webber C, Vipparti V, Choi HU, Rosenberg LC, Banerjee S.
    J Immunol; 1992 Apr 01; 148(7):2090-6. PubMed ID: 1372024
    [Abstract] [Full Text] [Related]

  • 13. Molecular manipulation with the arthritogenic epitopes of the G1 domain of human cartilage proteoglycan aggrecan.
    Murad YM, Szabó Z, Ludányi K, Glant TT.
    Clin Exp Immunol; 2005 Nov 01; 142(2):303-11. PubMed ID: 16232217
    [Abstract] [Full Text] [Related]

  • 14. Predominant cellular immune response to the cartilage autoantigenic G1 aggrecan in ankylosing spondylitis and rheumatoid arthritis.
    Zou J, Zhang Y, Thiel A, Rudwaleit M, Shi SL, Radbruch A, Poole R, Braun J, Sieper J.
    Rheumatology (Oxford); 2003 Jul 01; 42(7):846-55. PubMed ID: 12730543
    [Abstract] [Full Text] [Related]

  • 15. Monoclonal antibodies reactive with keratan sulfate-bearing tryptic fragments of bovine nasal cartilage proteoglycan.
    Keiser HD, Diamond BA.
    Connect Tissue Res; 1987 Jul 01; 16(2):131-41. PubMed ID: 2952451
    [Abstract] [Full Text] [Related]

  • 16. Isolation and characteristics of autoreactive T cells specific to aggrecan G1 domain from rheumatoid arthritis patients.
    Li NL, Zhang DQ, Zhou KY, Cartman A, Leroux JY, Poole AR, Zhang YP.
    Cell Res; 2000 Mar 01; 10(1):39-49. PubMed ID: 10765982
    [Abstract] [Full Text] [Related]

  • 17. T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.
    Buzás EI, Végvári A, Murad YM, Finnegan A, Mikecz K, Glant TT.
    Cell Immunol; 2005 Jun 01; 235(2):98-108. PubMed ID: 16185673
    [Abstract] [Full Text] [Related]

  • 18. Mature bovine articular cartilage contains abundant aggrecan that is C-terminally truncated at Ala719-Ala720, a site which is readily cleaved by m-calpain.
    Oshita H, Sandy JD, Suzuki K, Akaike A, Bai Y, Sasaki T, Shimizu K.
    Biochem J; 2004 Aug 15; 382(Pt 1):253-9. PubMed ID: 15175011
    [Abstract] [Full Text] [Related]

  • 19. Association of the aggrecan keratan sulfate-rich region with collagen in bovine articular cartilage.
    Hedlund H, Hedbom E, Heineg rd D, Mengarelli-Widholm S, Reinholt FP, Svensson O.
    J Biol Chem; 1999 Feb 26; 274(9):5777-81. PubMed ID: 10026199
    [Abstract] [Full Text] [Related]

  • 20. Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
    Brennan FR, Mikecz K, Buzás EI, Ragasa D, Cs-Szabó G, Negroiu G, Glant TT.
    Clin Exp Immunol; 1995 Sep 26; 101(3):414-21. PubMed ID: 7664487
    [Abstract] [Full Text] [Related]

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