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456 related items for PubMed ID: 8611180

  • 1. Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors.
    Serveau C, Lalmanach G, Juliano MA, Scharfstein J, Juliano L, Gauthier F.
    Biochem J; 1996 Feb 01; 313 ( Pt 3)(Pt 3):951-6. PubMed ID: 8611180
    [Abstract] [Full Text] [Related]

  • 2. Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi.
    Lalmanach G, Mayer R, Serveau C, Scharfstein J, Gauthier F.
    Biochem J; 1996 Sep 01; 318 ( Pt 2)(Pt 2):395-9. PubMed ID: 8809025
    [Abstract] [Full Text] [Related]

  • 3. Discrimination of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, and mammalian cathepsins B and L, by a pH-inducible fluorogenic substrate of trypanosomal cysteine proteinases.
    Serveau C, Lalmanach G, Hirata I, Scharfstein J, Juliano MA, Gauthier F.
    Eur J Biochem; 1999 Jan 01; 259(1-2):275-80. PubMed ID: 9914503
    [Abstract] [Full Text] [Related]

  • 4. A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi.
    Chagas JR, Authie E, Serveau C, Lalmanach G, Juliano L, Gauthier F.
    Mol Biochem Parasitol; 1997 Sep 01; 88(1-2):85-94. PubMed ID: 9274870
    [Abstract] [Full Text] [Related]

  • 5. Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases.
    Lalmanach G, Serveau C, Brillard-Bourdet M, Chagas JR, Mayer R, Juliano L, Gauthier F.
    J Protein Chem; 1995 Nov 01; 14(8):645-53. PubMed ID: 8747425
    [Abstract] [Full Text] [Related]

  • 6. Comparison of the specificity, stability and individual rate constants with respective activation parameters for the peptidase activity of cruzipain and its recombinant form, cruzain, from Trypanosoma cruzi.
    Judice WA, Cezari MH, Lima AP, Scharfstein J, Chagas JR, Tersariol IL, Juliano MA, Juliano L.
    Eur J Biochem; 2001 Dec 01; 268(24):6578-86. PubMed ID: 11737212
    [Abstract] [Full Text] [Related]

  • 7. Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.
    Nery ED, Juliano MA, Meldal M, Svendsen I, Scharfstein J, Walmsley A, Juliano L.
    Biochem J; 1997 Apr 15; 323 ( Pt 2)(Pt 2):427-33. PubMed ID: 9163334
    [Abstract] [Full Text] [Related]

  • 8. S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.
    Alves LC, Melo RL, Sanderson SJ, Mottram JC, Coombs GH, Caliendo G, Santagada V, Juliano L, Juliano MA.
    Eur J Biochem; 2001 Mar 15; 268(5):1206-12. PubMed ID: 11231271
    [Abstract] [Full Text] [Related]

  • 9. Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors.
    Lima AP, dos Reis FC, Serveau C, Lalmanach G, Juliano L, Ménard R, Vernet T, Thomas DY, Storer AC, Scharfstein J.
    Mol Biochem Parasitol; 2001 Apr 25; 114(1):41-52. PubMed ID: 11356512
    [Abstract] [Full Text] [Related]

  • 10. Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi.
    Del Nery E, Juliano MA, Lima AP, Scharfstein J, Juliano L.
    J Biol Chem; 1997 Oct 10; 272(41):25713-8. PubMed ID: 9325296
    [Abstract] [Full Text] [Related]

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  • 12. Inhibition of cruzipain, the major cysteine proteinase of the protozoan parasite, Trypanosoma cruzi, by proteinase inhibitors of the cystatin superfamily.
    Stoka V, Nycander M, Lenarcic B, Labriola C, Cazzulo JJ, Björk I, Turk V.
    FEBS Lett; 1995 Aug 14; 370(1-2):101-4. PubMed ID: 7649285
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  • 14. Grafting of features of cystatins C or B into the N-terminal region or second binding loop of cystatin A (stefin A) substantially enhances inhibition of cysteine proteinases.
    Pavlova A, Björk I.
    Biochemistry; 2003 Sep 30; 42(38):11326-33. PubMed ID: 14503883
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  • 16. Altered expression of cruzipain and a cathepsin B-like target in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine-proteinases.
    Yong V, Schmitz V, Vannier-Santos MA, de Lima AP, Lalmanach G, Juliano L, Gauthier F, Scharfstein J.
    Mol Biochem Parasitol; 2000 Jun 30; 109(1):47-59. PubMed ID: 10924756
    [Abstract] [Full Text] [Related]

  • 17. Trypanosoma cruzi: partial characterization of minor cruzipain isoforms non-adsorbed to Concanavalin A-Sepharose.
    Duschak VG, Barboza M, Couto AS.
    Exp Parasitol; 2003 Jun 30; 104(3-4):122-30. PubMed ID: 14552859
    [Abstract] [Full Text] [Related]

  • 18. The importance of the second hairpin loop of cystatin C for proteinase binding. Characterization of the interaction of Trp-106 variants of the inhibitor with cysteine proteinases.
    Björk I, Brieditis I, Raub-Segall E, Pol E, Håkansson K, Abrahamson M.
    Biochemistry; 1996 Aug 20; 35(33):10720-6. PubMed ID: 8718861
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases.
    Redzynia I, Ljunggren A, Bujacz A, Abrahamson M, Jaskolski M, Bujacz G.
    FEBS J; 2009 Feb 20; 276(3):793-806. PubMed ID: 19143838
    [Abstract] [Full Text] [Related]

  • 20. Some kinetic properties of a cysteine proteinase (cruzipain) from Trypanosoma cruzi.
    Cazzulo JJ, Cazzulo Franke MC, Martínez J, Franke de Cazzulo BM.
    Biochim Biophys Acta; 1990 Feb 09; 1037(2):186-91. PubMed ID: 2407295
    [Abstract] [Full Text] [Related]

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