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Journal Abstract Search

172 related items for PubMed ID: 8614985

  • 1. The novel protein kinase of the RR1 subunit of herpes simplex virus has autophosphorylation and transphosphorylation activity that differs in its ATP requirements for HSV-1 and HSV-2.
    Peng T, Hunter JR, Nelson JW.
    Virology; 1996 Feb 01; 216(1):184-96. PubMed ID: 8614985
    [Abstract] [Full Text] [Related]

  • 2. The 140-kDa RR1 protein from both HSV-1 and HSV-2 contains an intrinsic protein kinase activity capable of autophosphorylation but it is transphosphorylation defective.
    Ali MA.
    Virology; 1995 Mar 10; 207(2):409-16. PubMed ID: 7886945
    [Abstract] [Full Text] [Related]

  • 3. The transmembrane domain of the large subunit of HSV-2 ribonucleotide reductase (ICP10) is required for protein kinase activity and transformation-related signaling pathways that result in ras activation.
    Smith CC, Luo JH, Hunter JC, Ordonez JV, Aurelian L.
    Virology; 1994 May 01; 200(2):598-612. PubMed ID: 8178446
    [Abstract] [Full Text] [Related]

  • 4. The protein kinase activity of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) fused to the extracellular domain of the epidermal growth factor receptor is ligand-inducible.
    Smith CC, Luo JH, Aurelian L.
    Virology; 1996 Mar 15; 217(2):425-34. PubMed ID: 8610433
    [Abstract] [Full Text] [Related]

  • 5. The large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is associated with the virion tegument and has PK activity.
    Smith CC, Aurelian L.
    Virology; 1997 Aug 04; 234(2):235-42. PubMed ID: 9268154
    [Abstract] [Full Text] [Related]

  • 6. The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth.
    Smith CC, Peng T, Kulka M, Aurelian L.
    J Virol; 1998 Nov 04; 72(11):9131-41. PubMed ID: 9765459
    [Abstract] [Full Text] [Related]

  • 7. The transmembrane helical segment but not the invariant lysine is required for the kinase activity of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10).
    Luo JH, Aurelian L.
    J Biol Chem; 1992 May 15; 267(14):9645-53. PubMed ID: 1315764
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  • 9. ATP and SH3 binding sites in the protein kinase of the large subunit of herpes simplex virus type 2 of ribonucleotide reductase (ICP10).
    Nelson JW, Zhu J, Smith CC, Kulka M, Aurelian L.
    J Biol Chem; 1996 Jul 19; 271(29):17021-7. PubMed ID: 8663276
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  • 11. A truncated protein kinase domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) expressed in Escherichia coli.
    Luo JH, Smith CC, Kulka M, Aurelian L.
    J Biol Chem; 1991 Nov 05; 266(31):20976-83. PubMed ID: 1657940
    [Abstract] [Full Text] [Related]

  • 12. The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8.
    Dufour F, Sasseville AM, Chabaud S, Massie B, Siegel RM, Langelier Y.
    Apoptosis; 2011 Mar 05; 16(3):256-71. PubMed ID: 21107701
    [Abstract] [Full Text] [Related]

  • 13. A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus.
    Fu X, Tao L, Cai R, Prigge J, Zhang X.
    Mol Ther; 2006 May 05; 13(5):882-90. PubMed ID: 16569513
    [Abstract] [Full Text] [Related]

  • 14. Intracellular internalization and signaling pathways triggered by the large subunit of HSV-2 ribonucleotide reductase (ICP10).
    Hunter JC, Smith CC, Bose D, Kulka M, Broderick R, Aurelian L.
    Virology; 1995 Jul 10; 210(2):345-60. PubMed ID: 7618272
    [Abstract] [Full Text] [Related]

  • 15. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1.
    Perkins D, Pereira EF, Aurelian L.
    J Virol; 2003 Jan 10; 77(2):1292-305. PubMed ID: 12502846
    [Abstract] [Full Text] [Related]

  • 16. Purification and characterization of the protein kinase encoded by the UL13 gene of herpes simplex virus type 2.
    Daikoku T, Shibata S, Goshima F, Oshima S, Tsurumi T, Yamada H, Yamashita Y, Nishiyama Y.
    Virology; 1997 Aug 18; 235(1):82-93. PubMed ID: 9300039
    [Abstract] [Full Text] [Related]

  • 17. Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10).
    Aurelian L, Kokuba H, Smith CC.
    Vaccine; 1999 Apr 09; 17(15-16):1951-63. PubMed ID: 10217594
    [Abstract] [Full Text] [Related]

  • 18. Characterization of heterosubunit complexes formed by the R1 and R2 subunits of herpes simplex virus 1 and equine herpes virus 4 ribonucleotide reductase.
    Sun Y, Conner J.
    Biochem J; 2000 Apr 01; 347 Pt 1(Pt 1):97-104. PubMed ID: 10727407
    [Abstract] [Full Text] [Related]

  • 19. Expression of herpes simplex virus type 2 protein ICP10 PK rescues neurons from apoptosis due to serum deprivation or genetic defects.
    Perkins D, Yu Y, Bambrick LL, Yarowsky PJ, Aurelian L.
    Exp Neurol; 2002 Mar 01; 174(1):118-22. PubMed ID: 11869040
    [Abstract] [Full Text] [Related]

  • 20. Herpes simplex virus 2 VP22 phosphorylation induced by cellular and viral kinases does not influence intracellular localization.
    Geiss BJ, Cano GL, Tavis JE, Morrison LA.
    Virology; 2004 Dec 05; 330(1):74-81. PubMed ID: 15527835
    [Abstract] [Full Text] [Related]

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