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613 related items for PubMed ID: 8615631

  • 1. Novel trans platinum complexes: comparative in vitro and in vivo activity against platinum-sensitive and resistant murine tumours.
    Goddard PM, Orr RM, Valenti MR, Barnard CF, Murrer BA, Kelland LR, Harrap KR.
    Anticancer Res; 1996; 16(1):33-8. PubMed ID: 8615631
    [Abstract] [Full Text] [Related]

  • 2. Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.
    Kelland LR, Abel G, McKeage MJ, Jones M, Goddard PM, Valenti M, Murrer BA, Harrap KR.
    Cancer Res; 1993 Jun 01; 53(11):2581-6. PubMed ID: 8388318
    [Abstract] [Full Text] [Related]

  • 3. cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and pharmacokinetics in mice.
    Raynaud FI, Boxall FE, Goddard PM, Valenti M, Jones M, Murrer BA, Abrams M, Kelland LR.
    Clin Cancer Res; 1997 Nov 01; 3(11):2063-74. PubMed ID: 9815598
    [Abstract] [Full Text] [Related]

  • 4. The role of glutathione (GSH) in determining sensitivity to platinum drugs in vivo in platinum-sensitive and -resistant murine leukaemia and plasmacytoma and human ovarian carcinoma xenografts.
    Goddard P, Valenti M, Kelland LR.
    Anticancer Res; 1994 Nov 01; 14(3A):1065-70. PubMed ID: 8074451
    [Abstract] [Full Text] [Related]

  • 5. A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity.
    Kelland LR, Barnard CF, Mellish KJ, Jones M, Goddard PM, Valenti M, Bryant A, Murrer BA, Harrap KR.
    Cancer Res; 1994 Nov 01; 54(21):5618-22. PubMed ID: 7923207
    [Abstract] [Full Text] [Related]

  • 6. Cellular pharmacology of cis and trans pairs of platinum complexes in cisplatin-sensitive and -resistant human ovarian carcinoma cells.
    O'Neill CF, Hunakova L, Kelland LR.
    Chem Biol Interact; 1999 Nov 15; 123(1):11-29. PubMed ID: 10597899
    [Abstract] [Full Text] [Related]

  • 7. Circumvention of platinum resistance: structure-activity relationship for homologous series of ammine/amine platinum(II) complexes in L1210 cell lines.
    Yoshida M, Khokhar AR, Siddik ZH.
    Anticancer Drug Des; 1994 Oct 15; 9(5):425-34. PubMed ID: 7945726
    [Abstract] [Full Text] [Related]

  • 8. DNA-binding properties of novel cis- and trans platinum-based anticancer agents in 2 human ovarian carcinoma cell lines.
    Mellish KJ, Barnard CF, Murrer BA, Kelland LR.
    Int J Cancer; 1995 Sep 15; 62(6):717-23. PubMed ID: 7558420
    [Abstract] [Full Text] [Related]

  • 9. Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes.
    Siddik ZH, al-Baker S, Thai G, Khokhar AR.
    Anticancer Drug Des; 1994 Apr 15; 9(2):139-51. PubMed ID: 8166929
    [Abstract] [Full Text] [Related]

  • 10. Chemical and biological studies on a series of novel (trans-(1R,2R)-, trans-(1S,2S)-, and cis-1,2-diaminocyclohexane)platinum(IV) carboxylate complexes.
    Khokhar AR, al-Baker S, Shamsuddin S, Siddik ZH.
    J Med Chem; 1997 Jan 03; 40(1):112-6. PubMed ID: 9016335
    [Abstract] [Full Text] [Related]

  • 11. Axial ligands and alicyclic ring size modulate the activity and biochemical pharmacology of ammine/cycloalkylamine-platinum(IV) complexes in tumor cells resistant to cis-diamminedichloroplatinum(II) or trans-1R,2R-1S,2S-diaminocyclohexanetetrachloroplatinum(IV).
    Yoshida M, Khokhar AR, Siddik ZH.
    Cancer Res; 1994 Sep 01; 54(17):4691-7. PubMed ID: 8062266
    [Abstract] [Full Text] [Related]

  • 12. Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo.
    Siddik ZH, Thai G, Yoshida M, Zhang YP, Khokhar AR.
    Anticancer Drug Des; 1994 Dec 01; 9(6):495-509. PubMed ID: 7880375
    [Abstract] [Full Text] [Related]

  • 13. Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance.
    Kelland LR, Sharp SY, O'Neill CF, Raynaud FI, Beale PJ, Judson IR.
    J Inorg Biochem; 1999 Oct 01; 77(1-2):111-5. PubMed ID: 10626362
    [Abstract] [Full Text] [Related]

  • 14. Ascorbato(1,2-diaminocyclohexane):platinum(II) complexes, a new series of water-soluble antitumor drugs.
    Hacker MP, Khokhar AR, Brown DB, McCormack JJ, Krakoff IH.
    Cancer Res; 1985 Oct 01; 45(10):4748-53. PubMed ID: 4040806
    [Abstract] [Full Text] [Related]

  • 15. Transport of cisplatin and bis-acetato-ammine-dichlorocyclohexylamine Platinum(IV) (JM216) in human ovarian carcinoma cell lines: identification of a plasma membrane protein associated with cisplatin resistance.
    Sharp SY, Rogers PM, Kelland LR.
    Clin Cancer Res; 1995 Sep 01; 1(9):981-9. PubMed ID: 9816070
    [Abstract] [Full Text] [Related]

  • 16. Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
    Kelland LR, Mistry P, Abel G, Loh SY, O'Neill CF, Murrer BA, Harrap KR.
    Cancer Res; 1992 Jul 15; 52(14):3857-64. PubMed ID: 1617660
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, physical properties, and antitumor activity of tetraplatin and related tetrachloroplatinum(IV) stereoisomers of 1,2-diaminocyclohexane.
    Anderson WK, Quagliato DA, Haugwitz RD, Narayanan VL, Wolpert-DeFilippes MK.
    Cancer Treat Rep; 1986 Aug 15; 70(8):997-1002. PubMed ID: 3731155
    [Abstract] [Full Text] [Related]

  • 18. Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines.
    Yoshida M, Khokhar AR, Siddik ZH.
    Cancer Res; 1994 Jul 01; 54(13):3468-73. PubMed ID: 8012968
    [Abstract] [Full Text] [Related]

  • 19. Modulation of cytotoxicity and cellular pharmacology of 1,2-diaminocyclohexane platinum (IV) complexes mediated by axial and equatorial ligands.
    Kido Y, Khokhar AR, al-Baker S, Siddik ZH.
    Cancer Res; 1993 Oct 01; 53(19):4567-72. PubMed ID: 8402629
    [Abstract] [Full Text] [Related]

  • 20. The role of murine tumour models and their acquired platinum-resistant counterparts in the evaluation of novel platinum antitumour agents: a cautionary note.
    Goddard PM, Valenti MR, Harrap KR.
    Ann Oncol; 1991 Sep 01; 2(8):535-40. PubMed ID: 1793720
    [Abstract] [Full Text] [Related]

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