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218 related items for PubMed ID: 8615871

  • 1. Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    McNaught KS, Thull U, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa B, Jenner P, Marsden CD.
    Biochem Pharmacol; 1995 Nov 27; 50(11):1903-11. PubMed ID: 8615871
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    McNaught KS, Altomare C, Cellamare S, Carotti A, Thull U, Carrupt PA, Testa B, Jenner P, Marsden CD.
    Neuroreport; 1995 May 30; 6(8):1105-8. PubMed ID: 7662887
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    McNaught KS, Thull U, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa B, Jenner P, Marsden CD.
    Biochem Pharmacol; 1996 Jul 12; 52(1):29-34. PubMed ID: 8678905
    [Abstract] [Full Text] [Related]

  • 4. Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration.
    McNaught KS, Thull U, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa B, Jenner P, Marsden CD.
    Biochem Pharmacol; 1996 Jun 14; 51(11):1503-11. PubMed ID: 8630091
    [Abstract] [Full Text] [Related]

  • 5. Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain.
    Suzuki K, Mizuno Y, Yamauchi Y, Nagatsu T, Mitsuo Y.
    J Neurol Sci; 1992 Jun 14; 109(2):219-23. PubMed ID: 1353109
    [Abstract] [Full Text] [Related]

  • 6. Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    McNaught KS, Thull U, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa B, Jenner P, Marsden CD.
    Neurosci Lett; 1996 Mar 08; 206(1):37-40. PubMed ID: 8848276
    [Abstract] [Full Text] [Related]

  • 7. Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter.
    Storch A, Ott S, Hwang YI, Ortmann R, Hein A, Frenzel S, Matsubara K, Ohta S, Wolf HU, Schwarz J.
    Biochem Pharmacol; 2002 Mar 01; 63(5):909-20. PubMed ID: 11911843
    [Abstract] [Full Text] [Related]

  • 8. Nigral cell loss produced by infusion of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    McNaught KS, Thull U, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa B, Jenner P, Marsden CD.
    Neurodegeneration; 1996 Sep 01; 5(3):265-74. PubMed ID: 8910905
    [Abstract] [Full Text] [Related]

  • 9. Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease.
    McNaught KS, Carrupt PA, Altomare C, Cellamare S, Carotti A, Testa B, Jenner P, Marsden CD.
    Biochem Pharmacol; 1998 Oct 15; 56(8):921-33. PubMed ID: 9776302
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of mitochondrial succinate oxidation--similarities and differences between N-methylated beta-carbolines and MPP+.
    Fields JZ, Albores RR, Neafsey EJ, Collins MA.
    Arch Biochem Biophys; 1992 May 01; 294(2):539-43. PubMed ID: 1314543
    [Abstract] [Full Text] [Related]

  • 11. The endogenous amine 1-methyl-1,2,3,4- tetrahydroisoquinoline prevents the inhibition of complex I of the respiratory chain produced by MPP(+).
    Parrado J, Absi E, Ayala A, Castaño A, Cano J, Machado A.
    J Neurochem; 2000 Jul 01; 75(1):65-71. PubMed ID: 10854248
    [Abstract] [Full Text] [Related]

  • 12. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-like compounds on mitochondrial respiration.
    Suzuki K, Mizuno Y, Yoshida M.
    Adv Neurol; 1990 Jul 01; 53():215-8. PubMed ID: 2122645
    [Abstract] [Full Text] [Related]

  • 13. 1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol) is toxic to dopaminergic neuroblastoma SH-SY5Y cells via impairment of cellular energy metabolism.
    Storch A, Kaftan A, Burkhardt K, Schwarz J.
    Brain Res; 2000 Feb 07; 855(1):67-75. PubMed ID: 10650131
    [Abstract] [Full Text] [Related]

  • 14. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain.
    Mizuno Y, Sone N, Saitoh T.
    J Neurochem; 1987 Jun 07; 48(6):1787-93. PubMed ID: 3106573
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo.
    Nagatsu T, Hirata Y.
    Eur Neurol; 1987 Jun 07; 26 Suppl 1():11-5. PubMed ID: 2884110
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of mitochondrial respiration by 1,2,3,4-tetrahydroisoquinoline-like endogenous alkaloids in mouse brain.
    Suzuki K, Mizuno Y, Yoshida M.
    Neurochem Res; 1990 Jul 07; 15(7):705-10. PubMed ID: 1975653
    [Abstract] [Full Text] [Related]

  • 17. Intracerebral microdialysis neurotoxicity studies of quinoline and isoquinoline derivatives related to MPTP/MPP+.
    Booth RG, Castagnoli N, Rollema H.
    Neurosci Lett; 1989 May 22; 100(1-3):306-12. PubMed ID: 2788253
    [Abstract] [Full Text] [Related]

  • 18. Biosynthesis of a parkinsonism-preventing substance, 1-methyl-1,2,3,4-tetrahydroisoquinoline, is inhibited by parkinsonism-inducing compounds in rat brain mitochondrial fraction.
    Yamakawa T, Ohta S.
    Neurosci Lett; 1999 Jan 15; 259(3):157-60. PubMed ID: 10025582
    [Abstract] [Full Text] [Related]

  • 19. MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transport.
    Desai VG, Feuers RJ, Hart RW, Ali SF.
    Brain Res; 1996 Apr 09; 715(1-2):1-8. PubMed ID: 8739616
    [Abstract] [Full Text] [Related]

  • 20. Direct interaction between mitochondrial succinate-ubiquinone and ubiquinol-cytochrome c oxidoreductases probed by sensitivity to quinone-related inhibitors.
    Yamashita A, Miyoshi H, Hatano T, Iwamura H.
    J Biochem; 1996 Aug 09; 120(2):377-84. PubMed ID: 8889824
    [Abstract] [Full Text] [Related]

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