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340 related items for PubMed ID: 8619238

  • 1. Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.
    Boogaard PJ, Sumner SC, Bond JA.
    Toxicol Appl Pharmacol; 1996 Feb; 136(2):307-16. PubMed ID: 8619238
    [Abstract] [Full Text] [Related]

  • 2. Hepatic and pulmonary glutathione conjugation of 1,2:3,4-diepoxybutane in human, rat, and mouse in vitro.
    Boogaard PJ, Sumner SC, Turner MJ, Bond JA.
    Toxicology; 1996 Oct 28; 113(1-3):297-9. PubMed ID: 8901912
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.
    Csanády GA, Guengerich FP, Bond JA.
    Carcinogenesis; 1992 Jul 28; 13(7):1143-53. PubMed ID: 1638680
    [Abstract] [Full Text] [Related]

  • 4. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ, Follansbee MH, Bond JA.
    Carcinogenesis; 1995 Oct 28; 16(10):2287-93. PubMed ID: 7586124
    [Abstract] [Full Text] [Related]

  • 5. The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro.
    Boogaard PJ, Bond JA.
    Toxicol Appl Pharmacol; 1996 Dec 28; 141(2):617-27. PubMed ID: 8975787
    [Abstract] [Full Text] [Related]

  • 6. High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene.
    Himmelstein MW, Asgharian B, Bond JA.
    Toxicol Appl Pharmacol; 1995 Jun 28; 132(2):281-8. PubMed ID: 7785055
    [Abstract] [Full Text] [Related]

  • 7. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.
    Himmelstein MW, Turner MJ, Asgharian B, Bond JA.
    Carcinogenesis; 1994 Aug 28; 15(8):1479-86. PubMed ID: 8055623
    [Abstract] [Full Text] [Related]

  • 8. 1,3-Butadiene metabolism by lung airways isolated from mice and rats.
    Seaton MJ, Plopper CG, Bond JA.
    Toxicology; 1996 Oct 28; 113(1-3):314-7. PubMed ID: 8901916
    [Abstract] [Full Text] [Related]

  • 9. Stereochemical aspects of the conjugation of epoxide metabolites of butadiene with glutathione in rat liver cytosol and freshly isolated rat hepatocytes.
    Nieusma JL, Claffey DJ, Ruth JA, Ross D.
    Toxicol Sci; 1998 Jun 28; 43(2):102-9. PubMed ID: 9710951
    [Abstract] [Full Text] [Related]

  • 10. Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways.
    Kemper RA, Krause RJ, Elfarra AA.
    Drug Metab Dispos; 2001 Jun 28; 29(6):830-6. PubMed ID: 11353751
    [Abstract] [Full Text] [Related]

  • 11. Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity.
    Sharer JE, Duescher RJ, Elfarra AA.
    Drug Metab Dispos; 1992 Jun 28; 20(5):658-64. PubMed ID: 1358569
    [Abstract] [Full Text] [Related]

  • 12. Characterization of urinary metabolites from Sprague-Dawley rats and B6C3F1 mice exposed to [1,2,3,4-13C]butadiene.
    Nauhaus SK, Fennell TR, Asgharian B, Bond JA, Sumner SC.
    Chem Res Toxicol; 1996 Jun 28; 9(4):764-73. PubMed ID: 8831821
    [Abstract] [Full Text] [Related]

  • 13. First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice.
    Filser JG, Faller TH, Bhowmik S, Schuster A, Kessler W, Pütz C, Csanády GA.
    Chem Biol Interact; 2001 Jun 01; 135-136():249-65. PubMed ID: 11397395
    [Abstract] [Full Text] [Related]

  • 14. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF, Health Review Committee.
    Res Rep Health Eff Inst; 2009 Aug 01; (144):3-79. PubMed ID: 20017413
    [Abstract] [Full Text] [Related]

  • 15. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.
    Johanson G, Filser JG.
    Arch Toxicol; 1993 Aug 01; 67(3):151-63. PubMed ID: 8494494
    [Abstract] [Full Text] [Related]

  • 16. Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism.
    Elfarra AA, Krause RJ, Kemper RA.
    Chem Biol Interact; 2001 Jun 01; 135-136():239-48. PubMed ID: 11397394
    [Abstract] [Full Text] [Related]

  • 17. Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure.
    Koivisto P, Kilpeläinen I, Rasanen I, Adler ID, Pacchierotti F, Peltonen K.
    Carcinogenesis; 1999 Jul 01; 20(7):1253-9. PubMed ID: 10383898
    [Abstract] [Full Text] [Related]

  • 18. In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data.
    Medinsky MA, Leavens TL, Csanády GA, Gargas ML, Bond JA.
    Carcinogenesis; 1994 Jul 01; 15(7):1329-40. PubMed ID: 8033308
    [Abstract] [Full Text] [Related]

  • 19. Epidemiological and mechanistic data suggest that 1,3-butadiene will not be carcinogenic to humans at exposures likely to be encountered in the environment or workplace.
    Bond JA, Recio L, Andjelkovich D.
    Carcinogenesis; 1995 Feb 01; 16(2):165-71. PubMed ID: 7859344
    [Abstract] [Full Text] [Related]

  • 20. In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
    Motwani HV, Törnqvist M.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):276-84. PubMed ID: 25448046
    [Abstract] [Full Text] [Related]

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