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323 related items for PubMed ID: 8621421

  • 1. Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor.
    Ward CW, Gough KH, Rashke M, Wan SS, Tribbick G, Wang J.
    J Biol Chem; 1996 Mar 08; 271(10):5603-9. PubMed ID: 8621421
    [Abstract] [Full Text] [Related]

  • 2. Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.
    Sasaoka T, Ishihara H, Sawa T, Ishiki M, Morioka H, Imamura T, Usui I, Takata Y, Kobayashi M.
    J Biol Chem; 1996 Aug 16; 271(33):20082-7. PubMed ID: 8702728
    [Abstract] [Full Text] [Related]

  • 3. SH-PTP2/Syp SH2 domain binding specificity is defined by direct interactions with platelet-derived growth factor beta-receptor, epidermal growth factor receptor, and insulin receptor substrate-1-derived phosphopeptides.
    Case RD, Piccione E, Wolf G, Benett AM, Lechleider RJ, Neel BG, Shoelson SE.
    J Biol Chem; 1994 Apr 08; 269(14):10467-74. PubMed ID: 8144631
    [Abstract] [Full Text] [Related]

  • 4. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
    van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.
    Curr Biol; 1995 Apr 01; 5(4):404-12. PubMed ID: 7542991
    [Abstract] [Full Text] [Related]

  • 5. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor.
    Batzer AG, Rotin D, Ureña JM, Skolnik EY, Schlessinger J.
    Mol Cell Biol; 1994 Aug 01; 14(8):5192-201. PubMed ID: 7518560
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  • 8. Functional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptors.
    Ishihara H, Sasaoka T, Ishiki M, Takata Y, Imamura T, Usui I, Langlois WJ, Sawa T, Kobayashi M.
    J Biol Chem; 1997 Apr 04; 272(14):9581-6. PubMed ID: 9083103
    [Abstract] [Full Text] [Related]

  • 9. Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin.
    Pruett W, Yuan Y, Rose E, Batzer AG, Harada N, Skolnik EY.
    Mol Cell Biol; 1995 Mar 04; 15(3):1778-85. PubMed ID: 7862167
    [Abstract] [Full Text] [Related]

  • 10. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.
    Ong SH, Guy GR, Hadari YR, Laks S, Gotoh N, Schlessinger J, Lax I.
    Mol Cell Biol; 2000 Feb 04; 20(3):979-89. PubMed ID: 10629055
    [Abstract] [Full Text] [Related]

  • 11. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
    Inoue G, Cheatham B, Kahn CR.
    J Biol Chem; 1996 Nov 08; 271(45):28206-11. PubMed ID: 8910437
    [Abstract] [Full Text] [Related]

  • 12. Direct interaction between Shc and the platelet-derived growth factor beta-receptor.
    Yokote K, Mori S, Hansen K, McGlade J, Pawson T, Heldin CH, Claesson-Welsh L.
    J Biol Chem; 1994 May 27; 269(21):15337-43. PubMed ID: 8195171
    [Abstract] [Full Text] [Related]

  • 13. Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling.
    Kim B, Cheng HL, Margolis B, Feldman EL.
    J Biol Chem; 1998 Dec 18; 273(51):34543-50. PubMed ID: 9852124
    [Abstract] [Full Text] [Related]

  • 14. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
    Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M.
    Mol Cell Biol; 1994 Oct 18; 14(10):6674-82. PubMed ID: 7935386
    [Abstract] [Full Text] [Related]

  • 15. PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities.
    Wolf G, Trüb T, Ottinger E, Groninga L, Lynch A, White MF, Miyazaki M, Lee J, Shoelson SE.
    J Biol Chem; 1995 Nov 17; 270(46):27407-10. PubMed ID: 7499194
    [Abstract] [Full Text] [Related]

  • 16. Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site.
    van der Geer P, Wiley S, Pawson T.
    Oncogene; 1999 May 20; 18(20):3071-5. PubMed ID: 10340378
    [Abstract] [Full Text] [Related]

  • 17. Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cells. Identification of a new Grb2.Sos1 binding site.
    Thomas D, Bradshaw RA.
    J Biol Chem; 1997 Aug 29; 272(35):22293-9. PubMed ID: 9268379
    [Abstract] [Full Text] [Related]

  • 18. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM, Lorenzo M, Pons S, White MF, Benito M.
    Mol Endocrinol; 1998 May 29; 12(5):688-97. PubMed ID: 9605931
    [Abstract] [Full Text] [Related]

  • 19. Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
    van der Geer P, Wiley S, Gish GD, Lai VK, Stephens R, White MF, Kaplan D, Pawson T.
    Proc Natl Acad Sci U S A; 1996 Feb 06; 93(3):963-8. PubMed ID: 8577769
    [Abstract] [Full Text] [Related]

  • 20. Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo.
    Isakoff SJ, Yu YP, Su YC, Blaikie P, Yajnik V, Rose E, Weidner KM, Sachs M, Margolis B, Skolnik EY.
    J Biol Chem; 1996 Feb 23; 271(8):3959-62. PubMed ID: 8626723
    [Abstract] [Full Text] [Related]

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