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135 related items for PubMed ID: 8621530

  • 1. Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus.
    Hansen H, Svensson U, Zhu J, Laviola L, Giorgino F, Wolf G, Smith RJ, Riedel H.
    J Biol Chem; 1996 Apr 12; 271(15):8882-6. PubMed ID: 8621530
    [Abstract] [Full Text] [Related]

  • 2. Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology and SH2 domains.
    He W, Rose DW, Olefsky JM, Gustafson TA.
    J Biol Chem; 1998 Mar 20; 273(12):6860-7. PubMed ID: 9506989
    [Abstract] [Full Text] [Related]

  • 3. Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis.
    Wang J, Dai H, Yousaf N, Moussaif M, Deng Y, Boufelliga A, Swamy OR, Leone ME, Riedel H.
    Mol Cell Biol; 1999 Sep 20; 19(9):6217-28. PubMed ID: 10454568
    [Abstract] [Full Text] [Related]

  • 4. Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling.
    O'Neill TJ, Rose DW, Pillay TS, Hotta K, Olefsky JM, Gustafson TA.
    J Biol Chem; 1996 Sep 13; 271(37):22506-13. PubMed ID: 8798417
    [Abstract] [Full Text] [Related]

  • 5. Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.
    Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE.
    J Biol Chem; 1997 Jan 31; 272(5):2659-67. PubMed ID: 9006901
    [Abstract] [Full Text] [Related]

  • 6. Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action.
    Deng Y, Bhattacharya S, Swamy OR, Tandon R, Wang Y, Janda R, Riedel H.
    J Biol Chem; 2003 Oct 10; 278(41):39311-22. PubMed ID: 12783867
    [Abstract] [Full Text] [Related]

  • 7. Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter.
    Wang J, Riedel H.
    J Biol Chem; 1998 Feb 06; 273(6):3136-9. PubMed ID: 9452421
    [Abstract] [Full Text] [Related]

  • 8. Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP.
    Staubs PA, Reichart DR, Saltiel AR, Milarski KL, Maegawa H, Berhanu P, Olefsky JM, Seely BL.
    J Biol Chem; 1994 Nov 04; 269(44):27186-92. PubMed ID: 7525547
    [Abstract] [Full Text] [Related]

  • 9. Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10.
    Langlais P, Dong LQ, Ramos FJ, Hu D, Li Y, Quon MJ, Liu F.
    Mol Endocrinol; 2004 Feb 04; 18(2):350-8. PubMed ID: 14615605
    [Abstract] [Full Text] [Related]

  • 10. Site-directed mutagenesis and yeast two-hybrid studies of the insulin and insulin-like growth factor-1 receptors: the Src homology-2 domain-containing protein hGrb10 binds to the autophosphorylated tyrosine residues in the kinase domain of the insulin receptor.
    Dong LQ, Farris S, Christal J, Liu F.
    Mol Endocrinol; 1997 Nov 04; 11(12):1757-65. PubMed ID: 9369444
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of hGrb10 binding to the insulin receptor by functional domain-mediated oligomerization.
    Dong LQ, Porter S, Hu D, Liu F.
    J Biol Chem; 1998 Jul 10; 273(28):17720-5. PubMed ID: 9651371
    [Abstract] [Full Text] [Related]

  • 12. Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity.
    Stein EG, Ghirlando R, Hubbard SR.
    J Biol Chem; 2003 Apr 11; 278(15):13257-64. PubMed ID: 12551896
    [Abstract] [Full Text] [Related]

  • 13. In vitro association of the phosphatidylinositol 3-kinase regulatory subunit (p85) with the human insulin receptor.
    Ottinger EA, Hui TY, Man Z, Barany G, Bernlohr DA.
    Int J Pept Protein Res; 1995 Nov 11; 46(5):346-53. PubMed ID: 8567177
    [Abstract] [Full Text] [Related]

  • 14. Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases.
    Nantel A, Mohammad-Ali K, Sherk J, Posner BI, Thomas DY.
    J Biol Chem; 1998 Apr 24; 273(17):10475-84. PubMed ID: 9553107
    [Abstract] [Full Text] [Related]

  • 15. Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor.
    Wick KR, Werner ED, Langlais P, Ramos FJ, Dong LQ, Shoelson SE, Liu F.
    J Biol Chem; 2003 Mar 07; 278(10):8460-7. PubMed ID: 12493740
    [Abstract] [Full Text] [Related]

  • 16. Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10.
    Dey BR, Frick K, Lopaczynski W, Nissley SP, Furlanetto RW.
    Mol Endocrinol; 1996 Jun 07; 10(6):631-41. PubMed ID: 8776723
    [Abstract] [Full Text] [Related]

  • 17. Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein.
    Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, Olefsky JM.
    J Biol Chem; 1995 Aug 11; 270(32):19151-7. PubMed ID: 7642582
    [Abstract] [Full Text] [Related]

  • 18. The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors.
    Stein EG, Gustafson TA, Hubbard SR.
    FEBS Lett; 2001 Mar 30; 493(2-3):106-11. PubMed ID: 11287005
    [Abstract] [Full Text] [Related]

  • 19. IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.
    Myers MG, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, Schaffhausen B, White MF.
    Proc Natl Acad Sci U S A; 1992 Nov 01; 89(21):10350-4. PubMed ID: 1332046
    [Abstract] [Full Text] [Related]

  • 20. Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor.
    Ward CW, Gough KH, Rashke M, Wan SS, Tribbick G, Wang J.
    J Biol Chem; 1996 Mar 08; 271(10):5603-9. PubMed ID: 8621421
    [Abstract] [Full Text] [Related]

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