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134 related items for PubMed ID: 8621711

  • 1. Heparinase I from Flavobacterium heparinum. Mapping and characterization of the heparin binding domain.
    Sasisekharan R, Venkataraman G, Godavarti R, Ernst S, Cooney CL, Langer R.
    J Biol Chem; 1996 Feb 09; 271(6):3124-31. PubMed ID: 8621711
    [Abstract] [Full Text] [Related]

  • 2. Heparinase I from Flavobacterium heparinum. Identification of a critical histidine residue essential for catalysis as probed by chemical modification and site-directed mutagenesis.
    Godavarti R, Cooney CL, Langer R, Sasisekharan R.
    Biochemistry; 1996 May 28; 35(21):6846-52. PubMed ID: 8639636
    [Abstract] [Full Text] [Related]

  • 3. Cloning and expression of heparinase I gene from Flavobacterium heparinum.
    Sasisekharan R, Bulmer M, Moremen KW, Cooney CL, Langer R.
    Proc Natl Acad Sci U S A; 1993 Apr 15; 90(8):3660-4. PubMed ID: 8475114
    [Abstract] [Full Text] [Related]

  • 4. Heparinase I from Flavobacterium heparinum: the role of the cysteine residue in catalysis as probed by chemical modification and site-directed mutagenesis.
    Sasisekharan R, Leckband D, Godavarti R, Venkataraman G, Cooney CL, Langer R.
    Biochemistry; 1995 Nov 07; 34(44):14441-8. PubMed ID: 7578049
    [Abstract] [Full Text] [Related]

  • 5. Heparinase II from Flavobacterium heparinum. Role of cysteine in enzymatic activity as probed by chemical modification and site- directed mutagenesis.
    Shriver Z, Hu Y, Pojasek K, Sasisekharan R.
    J Biol Chem; 1998 Sep 04; 273(36):22904-12. PubMed ID: 9722510
    [Abstract] [Full Text] [Related]

  • 6. Heparinase I from Flavobacterium heparinum. Role of positive charge in enzymatic activity.
    Godavarti R, Sasisekharan R.
    J Biol Chem; 1998 Jan 02; 273(1):248-55. PubMed ID: 9417072
    [Abstract] [Full Text] [Related]

  • 7. Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum.
    Ernst S, Venkataraman G, Winkler S, Godavarti R, Langer R, Cooney CL, Sasisekharan R.
    Biochem J; 1996 Apr 15; 315 ( Pt 2)(Pt 2):589-97. PubMed ID: 8615834
    [Abstract] [Full Text] [Related]

  • 8. The calcium-binding sites of heparinase I from Flavobacterium heparinum are essential for enzymatic activity.
    Liu D, Shriver Z, Godavarti R, Venkataraman G, Sasisekharan R.
    J Biol Chem; 1999 Feb 12; 274(7):4089-95. PubMed ID: 9933602
    [Abstract] [Full Text] [Related]

  • 9. Heparinase III from Flavobacterium heparinum: cloning and recombinant expression in Escherichia coli.
    Godavarti R, Davis M, Venkataraman G, Cooney C, Langer R, Sasisekharan R.
    Biochem Biophys Res Commun; 1996 Aug 23; 225(3):751-8. PubMed ID: 8780685
    [Abstract] [Full Text] [Related]

  • 10. Heparinase II from Flavobacterium heparinum. Role of histidine residues in enzymatic activity as probed by chemical modification and site-directed mutagenesis.
    Shriver Z, Hu Y, Sasisekharan R.
    J Biol Chem; 1998 Apr 24; 273(17):10160-7. PubMed ID: 9553064
    [Abstract] [Full Text] [Related]

  • 11. A comparative analysis of the primary sequences and characteristics of heparinases I, II, and III from Flavobacterium heparinum.
    Godavarti R, Sasisekharan R.
    Biochem Biophys Res Commun; 1996 Dec 24; 229(3):770-7. PubMed ID: 8954971
    [Abstract] [Full Text] [Related]

  • 12. Biochemical investigations and mapping of the calcium-binding sites of heparinase I from Flavobacterium heparinum.
    Shriver Z, Liu D, Hu Y, Sasisekharan R.
    J Biol Chem; 1999 Feb 12; 274(7):4082-8. PubMed ID: 9933601
    [Abstract] [Full Text] [Related]

  • 13. Histidine 295 and histidine 510 are crucial for the enzymatic degradation of heparan sulfate by heparinase III.
    Pojasek K, Shriver Z, Hu Y, Sasisekharan R.
    Biochemistry; 2000 Apr 11; 39(14):4012-9. PubMed ID: 10747789
    [Abstract] [Full Text] [Related]

  • 14. Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate.
    Shaya D, Zhao W, Garron ML, Xiao Z, Cui Q, Zhang Z, Sulea T, Linhardt RJ, Cygler M.
    J Biol Chem; 2010 Jun 25; 285(26):20051-61. PubMed ID: 20404324
    [Abstract] [Full Text] [Related]

  • 15. Examination of the substrate specificity of heparin and heparan sulfate lyases.
    Linhardt RJ, Turnbull JE, Wang HM, Loganathan D, Gallagher JT.
    Biochemistry; 1990 Mar 13; 29(10):2611-7. PubMed ID: 2334685
    [Abstract] [Full Text] [Related]

  • 16. Purification and characterization of heparin lyases from Flavobacterium heparinum.
    Lohse DL, Linhardt RJ.
    J Biol Chem; 1992 Dec 05; 267(34):24347-55. PubMed ID: 1332952
    [Abstract] [Full Text] [Related]

  • 17. Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product.
    Shaya D, Tocilj A, Li Y, Myette J, Venkataraman G, Sasisekharan R, Cygler M.
    J Biol Chem; 2006 Jun 02; 281(22):15525-35. PubMed ID: 16565082
    [Abstract] [Full Text] [Related]

  • 18. Mode of action of heparin lyase on heparin.
    Linhardt RJ, Fitzgerald GL, Cooney CL, Langer R.
    Biochim Biophys Acta; 1982 Apr 03; 702(2):197-203. PubMed ID: 7082675
    [Abstract] [Full Text] [Related]

  • 19. Purification and characterization of a novel heparinase.
    Böhmer LH, Pitout MJ, Steyn PL, Visser L.
    J Biol Chem; 1990 Aug 15; 265(23):13609-17. PubMed ID: 2166036
    [Abstract] [Full Text] [Related]

  • 20. Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.
    Su H, Blain F, Musil RA, Zimmermann JJ, Gu K, Bennett DC.
    Appl Environ Microbiol; 1996 Aug 15; 62(8):2723-34. PubMed ID: 8702264
    [Abstract] [Full Text] [Related]

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