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502 related items for PubMed ID: 8622964

  • 1.
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  • 3. Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse.
    D'Alessio DA, Verchere CB, Kahn SE, Hoagland V, Baskin DG, Palmiter RD, Ensinck JW.
    Diabetes; 1994 Dec; 43(12):1457-61. PubMed ID: 7958499
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  • 4. [Construction of transgenic mouse system expressing human islet amyloid polypeptide (IAPP)/amylin].
    Yagui K, Kanatsuka A, Makino H.
    Nihon Rinsho; 1994 Oct; 52(10):2746-50. PubMed ID: 7983808
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  • 5. beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
    Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.
    Diabetes; 2000 Dec; 49(12):2056-62. PubMed ID: 11118007
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  • 6. Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans.
    de Koning EJ, Höppener JW, Verbeek JS, Oosterwijk C, van Hulst KL, Baker CA, Lips CJ, Morris JF, Clark A.
    Diabetes; 1994 May; 43(5):640-4. PubMed ID: 8168639
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  • 7. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
    de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS.
    Proc Natl Acad Sci U S A; 1994 Aug 30; 91(18):8467-71. PubMed ID: 8078905
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  • 8. Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
    Höppener JW, Oosterwijk C, Nieuwenhuis MG, Posthuma G, Thijssen JH, Vroom TM, Ahrén B, Lips CJ.
    Diabetologia; 1999 Apr 30; 42(4):427-34. PubMed ID: 10230646
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  • 9. Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.
    Janson J, Soeller WC, Roche PC, Nelson RT, Torchia AJ, Kreutter DK, Butler PC.
    Proc Natl Acad Sci U S A; 1996 Jul 09; 93(14):7283-8. PubMed ID: 8692984
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  • 10. Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus.
    O'Brien TD, Butler PC, Westermark P, Johnson KH.
    Vet Pathol; 1993 Jul 09; 30(4):317-32. PubMed ID: 8212454
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  • 11. Expression of human islet amyloid polypeptide/amylin impairs insulin secretion in mouse pancreatic beta cells.
    Tokuyama T, Yagui K, Yamaguchi T, Huang CI, Kuramoto N, Shimada F, Miyazaki J, Horie H, Saito Y, Makino H, Kanatsuka A.
    Metabolism; 1997 Sep 09; 46(9):1044-51. PubMed ID: 9284894
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  • 12. Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
    Jaikaran ET, Clark A.
    Biochim Biophys Acta; 2001 Nov 29; 1537(3):179-203. PubMed ID: 11731221
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  • 13. Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.
    Paulsson JF, Andersson A, Westermark P, Westermark GT.
    Diabetologia; 2006 Jun 29; 49(6):1237-46. PubMed ID: 16570161
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  • 14. Islet amyloid polypeptide and type 2 diabetes.
    Marzban L, Park K, Verchere CB.
    Exp Gerontol; 2003 Apr 29; 38(4):347-51. PubMed ID: 12670620
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  • 15. Chronic overproduction of islet amyloid polypeptide/amylin in transgenic mice: lysosomal localization of human islet amyloid polypeptide and lack of marked hyperglycaemia or hyperinsulinaemia.
    Höppener JW, Verbeek JS, de Koning EJ, Oosterwijk C, van Hulst KL, Visser-Vernooy HJ, Hofhuis FM, van Gaalen S, Berends MJ, Hackeng WH.
    Diabetologia; 1993 Dec 29; 36(12):1258-65. PubMed ID: 8307253
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  • 16. Molecular physiology of the islet amyloid polypeptide (IAPP)/amylin gene in man, rat, and transgenic mice.
    Höppener JW, Oosterwijk C, van Hulst KL, Verbeek JS, Capel PJ, de Koning EJ, Clark A, Jansz HS, Lips CJ.
    J Cell Biochem; 1994 Dec 29; 55 Suppl():39-53. PubMed ID: 7929617
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  • 17. Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.
    Andrikopoulos S, Verchere CB, Teague JC, Howell WM, Fujimoto WY, Wight TN, Kahn SE.
    Diabetes; 1999 Oct 29; 48(10):1962-70. PubMed ID: 10512360
    [Abstract] [Full Text] [Related]

  • 18. Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.
    Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC.
    Diabetes; 2004 Jun 29; 53(6):1509-16. PubMed ID: 15161755
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  • 19. Amyloid formation in response to beta cell stress occurs in vitro, but not in vivo, in islets of transgenic mice expressing human islet amyloid polypeptide.
    Westermark G, Arora MB, Fox N, Carroll R, Chan SJ, Westermark P, Steiner DF.
    Mol Med; 1995 Jul 29; 1(5):542-53. PubMed ID: 8529120
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  • 20. Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.
    Matveyenko AV, Butler PC.
    ILAR J; 2006 Jul 29; 47(3):225-33. PubMed ID: 16804197
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