These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Potentiation of temozolomide and BCNU cytotoxicity by O(6)-benzylguanine: a comparative study in vitro. Wedge SR, Porteus JK, May BL, Newlands ES. Br J Cancer; 1996 Feb; 73(4):482-90. PubMed ID: 8595163 [Abstract] [Full Text] [Related]
8. Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme. Friedman HS, Dolan ME, Moschel RC, Pegg AE, Felker GM, Rich J, Bigner DD, Schold SC. J Natl Cancer Inst; 1992 Dec 16; 84(24):1926-31. PubMed ID: 1334154 [Abstract] [Full Text] [Related]
9. Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases. Cai Y, Wu MH, Xu-Welliver M, Pegg AE, Ludeman SM, Dolan ME. Cancer Res; 2000 Oct 01; 60(19):5464-9. PubMed ID: 11034089 [Abstract] [Full Text] [Related]
10. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine. Kokkinakis DM, Ahmed MM, Chendil D, Moschel RC, Pegg AE. Clin Cancer Res; 2003 Sep 01; 9(10 Pt 1):3801-7. PubMed ID: 14506174 [Abstract] [Full Text] [Related]
16. Synergistic efficacy of O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone. Gerson SL, Zborowska E, Norton K, Gordon NH, Willson JK. Biochem Pharmacol; 1993 Jan 26; 45(2):483-91. PubMed ID: 8435098 [Abstract] [Full Text] [Related]
17. Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N'-bis (2-chloroethyl)-N-nitrosourea. Loktionova NA, Pegg AE. Cancer Res; 1996 Apr 01; 56(7):1578-83. PubMed ID: 8603405 [Abstract] [Full Text] [Related]
18. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities. Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME. J Pharmacol Exp Ther; 2005 Dec 01; 315(3):1247-55. PubMed ID: 16126841 [Abstract] [Full Text] [Related]
19. Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations. Bacolod MD, Johnson SP, Pegg AE, Dolan ME, Moschel RC, Bullock NS, Fang Q, Colvin OM, Modrich P, Bigner DD, Friedman HS. Mol Cancer Ther; 2004 Sep 01; 3(9):1127-35. PubMed ID: 15367707 [Abstract] [Full Text] [Related]
20. Anti-neoplastic activity of sequenced administration of O6-benzylguanine, streptozotocin, and 1,3-bis(2-chloroethyl)-1-nitrosourea in vitro and in vivo. Marathi UK, Dolan ME, Erickson LC. Biochem Pharmacol; 1994 Nov 29; 48(11):2127-34. PubMed ID: 7802703 [Abstract] [Full Text] [Related] Page: [Next] [New Search]