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Journal Abstract Search

192 related items for PubMed ID: 8626409

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  • 5. Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data.
    Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR, Hamel E.
    J Biol Chem; 1991 Aug 25; 266(24):15882-9. PubMed ID: 1874739
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  • 6. Interactions of the sponge-derived antimitotic tripeptide hemiasterlin with tubulin: comparison with dolastatin 10 and cryptophycin 1.
    Bai R, Durso NA, Sackett DL, Hamel E.
    Biochemistry; 1999 Oct 26; 38(43):14302-10. PubMed ID: 10572005
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  • 8. Interaction of the antitumor compound cryptophycin-52 with tubulin.
    Panda D, Ananthnarayan V, Larson G, Shih C, Jordan MA, Wilson L.
    Biochemistry; 2000 Nov 21; 39(46):14121-7. PubMed ID: 11087360
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  • 9. In vitro effect of cryptophycin 52 on microtubule assembly and tubulin: molecular modeling of the mechanism of action of a new antimitotic drug.
    Barbier P, Gregoire C, Devred F, Sarrazin M, Peyrot V.
    Biochemistry; 2001 Nov 13; 40(45):13510-9. PubMed ID: 11695898
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  • 10. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
    Prota AE, Danel F, Bachmann F, Bargsten K, Buey RM, Pohlmann J, Reinelt S, Lane H, Steinmetz MO.
    J Mol Biol; 2014 Apr 17; 426(8):1848-60. PubMed ID: 24530796
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  • 11. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.
    Bai RL, Pettit GR, Hamel E.
    J Biol Chem; 1990 Oct 05; 265(28):17141-9. PubMed ID: 2211617
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  • 12. Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
    Bai R, Friedman SJ, Pettit GR, Hamel E.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2637-45. PubMed ID: 1632820
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  • 13. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 23; 44(4):757-66. PubMed ID: 8232226
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  • 14. Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule ends.
    Panda D, DeLuca K, Williams D, Jordan MA, Wilson L.
    Proc Natl Acad Sci U S A; 1998 Aug 04; 95(16):9313-8. PubMed ID: 9689077
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  • 15. Cryptophycin: a new antimicrotubule agent active against drug-resistant cells.
    Smith CD, Zhang X, Mooberry SL, Patterson GM, Moore RE.
    Cancer Res; 1994 Jul 15; 54(14):3779-84. PubMed ID: 7913408
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  • 16. Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction.
    Bai R, Schwartz RE, Kepler JA, Pettit GR, Hamel E.
    Cancer Res; 1996 Oct 01; 56(19):4398-406. PubMed ID: 8813133
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  • 17. The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain.
    Bai R, Taylor GF, Cichacz ZA, Herald CL, Kepler JA, Pettit GR, Hamel E.
    Biochemistry; 1995 Aug 01; 34(30):9714-21. PubMed ID: 7626642
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  • 18. (-)-Phenylahistin arrests cells in mitosis by inhibiting tubulin polymerization.
    Kanoh K, Kohno S, Katada J, Takahashi J, Uno I.
    J Antibiot (Tokyo); 1999 Feb 01; 52(2):134-41. PubMed ID: 10344567
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  • 19. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
    Cruz-Monserrate Z, Vervoort HC, Bai R, Newman DJ, Howell SB, Los G, Mullaney JT, Williams MD, Pettit GR, Fenical W, Hamel E.
    Mol Pharmacol; 2003 Jun 01; 63(6):1273-80. PubMed ID: 12761336
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  • 20. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
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