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Journal Abstract Search

157 related items for PubMed ID: 8627550

  • 1. The 21-aminosteroid tirilazad mesylate protects against liver injury via membrane stabilization not inhibition of lipid peroxidation.
    Wang Y, Mathews WR, Guido DM, Jaeschke H.
    J Pharmacol Exp Ther; 1996 May; 277(2):714-20. PubMed ID: 8627550
    [Abstract] [Full Text] [Related]

  • 2. The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats.
    Liu P, Vonderfecht SL, McGuire GM, Fisher MA, Farhood A, Jaeschke H.
    J Pharmacol Exp Ther; 1994 Oct; 271(1):438-45. PubMed ID: 7965745
    [Abstract] [Full Text] [Related]

  • 3. The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F).
    Althaus JS, Andrus PK, Williams CM, VonVoigtlander PF, Cazers AR, Hall ED.
    Mol Chem Neuropathol; 1993 Oct; 20(2):147-62. PubMed ID: 8297419
    [Abstract] [Full Text] [Related]

  • 4. Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat.
    Smith SL, Andrus PK, Zhang JR, Hall ED.
    J Neurotrauma; 1994 Aug; 11(4):393-404. PubMed ID: 7837280
    [Abstract] [Full Text] [Related]

  • 5. Effects of tirilazad mesylate on postischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils.
    Hall ED, Pazara KE, Braughler JM.
    Stroke; 1991 Mar; 22(3):361-6. PubMed ID: 2003306
    [Abstract] [Full Text] [Related]

  • 6. Effects of the 21-amino steroid tirilazad mesylate (U-74006F) on brain damage and edema after perinatal hypoxia-ischemia in the rat.
    Bågenholm R, Andiné P, Hagberg H.
    Pediatr Res; 1996 Sep; 40(3):399-403. PubMed ID: 8865275
    [Abstract] [Full Text] [Related]

  • 7. Effect of endotoxin-enhanced hepatic reperfusion injury on endothelium-dependent relaxation in rat aorta.
    McKenna R, Laskey RE, Wang Y, Jaeschke H, Mathews WR.
    Shock; 1996 Aug; 6(2):106-11. PubMed ID: 8856844
    [Abstract] [Full Text] [Related]

  • 8. Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia.
    Park CK, Hall ED.
    Brain Res; 1994 May 09; 645(1-2):157-63. PubMed ID: 8062078
    [Abstract] [Full Text] [Related]

  • 9. Protective effects of tirilazad mesylate and metabolite U-89678 against blood-brain barrier damage after subarachnoid hemorrhage and lipid peroxidative neuronal injury.
    Smith SL, Scherch HM, Hall ED.
    J Neurosurg; 1996 Feb 09; 84(2):229-33. PubMed ID: 8592225
    [Abstract] [Full Text] [Related]

  • 10. Studies of ischemia-reperfusion injury in skeletal muscle: efficacy of 21-aminosteroids on microcirculation and muscle contraction after an extended period of warm ischemia.
    Korompilias AV, Chen LE, Seaber AV, Urbaniak JR.
    J Orthop Res; 1997 Jul 09; 15(4):512-8. PubMed ID: 9379260
    [Abstract] [Full Text] [Related]

  • 11. Lewis rat EAN is suppressed by the 21-aminosteroid tirilazad mesylate (U-74006F).
    Feasby TE, Hahn AF, Lovgren D, Wilkie L.
    Neuropathol Appl Neurobiol; 1994 Aug 09; 20(4):384-91. PubMed ID: 7808589
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of lipid peroxidation attenuates axotomy-induced apoptotic degeneration of facial motor neurons in neonatal rats.
    Hall ED, Smith SL, Oostveen JA.
    J Neurosci Res; 1996 May 01; 44(3):293-9. PubMed ID: 8723768
    [Abstract] [Full Text] [Related]

  • 13. The 21-aminosteroid 16-desmethyl tirilazad mesylate prevents necroinflammatory changes in experimental alcoholic liver disease.
    Sadrzadeh SM, Nanji AA.
    J Pharmacol Exp Ther; 1998 Jan 01; 284(1):406-12. PubMed ID: 9435204
    [Abstract] [Full Text] [Related]

  • 14. Effects of the lipid peroxidation inhibitor tirilazad mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion.
    Andrus PK, Taylor BM, Sun FF, Hall ED.
    Brain Res; 1994 Oct 03; 659(1-2):126-32. PubMed ID: 7820653
    [Abstract] [Full Text] [Related]

  • 15. Protective effect of a 21-aminosteroid against hemorrhage-induced ischemia-reperfusion injury in the rat stomach: role of lipid peroxidation.
    Cross JM, Smith GS, Russell DH, Nguyen PH, Mercer DW, Barreto JC, Miller TA.
    Shock; 1995 May 03; 3(5):385-90. PubMed ID: 7648342
    [Abstract] [Full Text] [Related]

  • 16. Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation.
    Campo GM, Squadrito F, Altavilla D, Squadrito G, Avenoso A, Canale P, Ioculano M, Sperandeo A, Caputi AP.
    J Pharmacol Exp Ther; 1996 Apr 03; 277(1):333-40. PubMed ID: 8613938
    [Abstract] [Full Text] [Related]

  • 17. Vascular effects of the 21-aminosteroid tirilazad mesylate: protection against oxidant stress.
    McKenna R, Munns PL, Leach KL, Mathews WR.
    Methods Find Exp Clin Pharmacol; 1995 May 03; 17(4):279-92. PubMed ID: 7475515
    [Abstract] [Full Text] [Related]

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  • 19. [Tirilazad mesylate (Freedox)--an effective inhibitor of lipid membrane peroxidation].
    Sániová B.
    Bratisl Lek Listy; 1997 Jun 03; 98(6):339-42. PubMed ID: 9333426
    [Abstract] [Full Text] [Related]

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