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Journal Abstract Search

148 related items for PubMed ID: 8627577

  • 1. Modulation of embryonic glutathione peroxidase activity and phenytoin teratogenicity by dietary deprivation of selenium in CD-1 mice.
    Ozolins TR, Siksay DL, Wells PG.
    J Pharmacol Exp Ther; 1996 May; 277(2):945-53. PubMed ID: 8627577
    [Abstract] [Full Text] [Related]

  • 2. Evidence for embryonic peroxidase-catalyzed bioactivation and glutathione-dependent cytoprotection in phenytoin teratogenicity: modulation by eicosatetraynoic acid and buthionine sulfoximine in murine embryo culture.
    Miranda AF, Wiley MJ, Wells PG.
    Toxicol Appl Pharmacol; 1994 Feb; 124(2):230-41. PubMed ID: 8122268
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  • 3. Enhancement of murine phenytoin teratogenicity by the gamma-glutamylcysteine synthetase inhibitor L-buthionine-(S,R)-sulfoximine and by the glutathione depletor diethyl maleate.
    Wong M, Helston LM, Wells PG.
    Teratology; 1989 Aug; 40(2):127-41. PubMed ID: 2772848
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  • 4. Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage.
    Azarbayjani F, Danielsson BR.
    Teratology; 2001 Mar; 63(3):152-60. PubMed ID: 11283972
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  • 5. Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
    Wong M, Wells PG.
    J Pharmacol Exp Ther; 1989 Jul; 250(1):336-42. PubMed ID: 2746506
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  • 6. Potential molecular targets mediating chemical teratogenesis: in vitro peroxidase-catalyzed phenytoin metabolism and oxidative damage to proteins and lipids in murine maternal hepatic microsomes and embryonic 9000g supernatant.
    Liu L, Wells PG.
    Toxicol Appl Pharmacol; 1995 Sep; 134(1):71-80. PubMed ID: 7676459
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  • 7. In vivo phenytoin-initiated oxidative damage to proteins and lipids in murine maternal hepatic and embryonic tissue organelles: potential molecular targets of chemical teratogenesis.
    Liu L, Wells PG.
    Toxicol Appl Pharmacol; 1994 Apr; 125(2):247-55. PubMed ID: 8171432
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  • 8. Pharmacological studies on the potentiation of phenytoin teratogenicity by acetaminophen.
    Lum JT, Wells PG.
    Teratology; 1986 Feb; 33(1):53-72. PubMed ID: 3738810
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  • 9. Antioxidant and GSH-related enzyme response to a single teratogenic exposure to the anticonvulsant phenytoin: temporospatial evaluation.
    Amicarelli F, Tiboni GM, Colafarina S, Bonfigli A, Iammarrone E, Miranda M, Di Ilio C.
    Teratology; 2000 Aug; 62(2):100-7. PubMed ID: 10931507
    [Abstract] [Full Text] [Related]

  • 10. Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity.
    Winn LM, Wells PG.
    Mol Pharmacol; 1995 Jul; 48(1):112-20. PubMed ID: 7623765
    [Abstract] [Full Text] [Related]

  • 11. Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity.
    Winn LM, Wells PG.
    Free Radic Biol Med; 1999 Feb; 26(3-4):266-74. PubMed ID: 9895216
    [Abstract] [Full Text] [Related]

  • 12. Evidence for lipoxygenase-catalyzed bioactivation of phenytoin to a teratogenic reactive intermediate: in vitro studies using linoleic acid-dependent soybean lipoxygenase, and in vivo studies using pregnant CD-1 mice.
    Yu WK, Wells PG.
    Toxicol Appl Pharmacol; 1995 Mar; 131(1):1-12. PubMed ID: 7878664
    [Abstract] [Full Text] [Related]

  • 13. Variable in vivo embryoprotective role for ataxia-telangiectasia-mutated against constitutive and phenytoin-enhanced oxidative stress in atm knockout mice.
    Bhuller Y, Jeng W, Wells PG.
    Toxicol Sci; 2006 Sep; 93(1):146-55. PubMed ID: 16714389
    [Abstract] [Full Text] [Related]

  • 14. Protective role of intraperitoneally administered vitamin E and selenium on the antioxidative defense mechanisms in rats with diabetes induced by streptozotocin.
    Naziroğlu M, Cay M.
    Biol Trace Elem Res; 2001 Feb; 79(2):149-59. PubMed ID: 11330521
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  • 16. The effects of gestational arsenic exposure and dietary selenium deficiency on selenium and selenoenzymes in maternal and fetal tissues in mice.
    Miyazaki K, Watanabe C, Mori K, Yoshida K, Ohtsuka R.
    Toxicology; 2005 Mar 30; 208(3):357-65. PubMed ID: 15695021
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