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Journal Abstract Search

408 related items for PubMed ID: 8627583

  • 1. Isosteric substitution of Asn5 in antagonists of oxytocin and vasopressin leads to highly selective and potent oxytocin and V1a receptor antagonists: new approaches for the design of potential tocolytics for preterm labor.
    Chan WY, Wo NC, Cheng LL, Manning M.
    J Pharmacol Exp Ther; 1996 May; 277(2):999-1003. PubMed ID: 8627583
    [Abstract] [Full Text] [Related]

  • 2. Design of oxytocin antagonists, which are more selective than atosiban.
    Manning M, Stoev S, Cheng LL, Wo NC, Chan WY.
    J Pept Sci; 2001 Sep; 7(9):449-65. PubMed ID: 11587184
    [Abstract] [Full Text] [Related]

  • 3. An exploration of the effects of L- and D-tetrahydroisoquinoline-3-carboxylic acid substitutions at positions 2, 3 and 7 in cyclic and linear antagonists of vasopressin and oxytocin and at position 3 in arginine vasopressin.
    Manning M, Cheng LL, Stoev S, Bankowski K, Przybyiski J, Klis WA, Sawyer WH, Wo NC, Chan WY.
    J Pept Sci; 1995 Sep; 1(1):66-79. PubMed ID: 9222985
    [Abstract] [Full Text] [Related]

  • 4. Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban.
    Manning M, Cheng LL, Stoev S, Wo NC, Chan WY, Szeto HH, Durroux T, Mouillac B, Barberis C.
    J Pept Sci; 2005 Oct; 11(10):593-608. PubMed ID: 15880385
    [Abstract] [Full Text] [Related]

  • 5. Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: comparisons with Atosiban.
    Manning M, Miteva K, Pancheva S, Stoev S, Wo NC, Chan WY.
    Int J Pept Protein Res; 1995 Oct; 46(3-4):244-52. PubMed ID: 8537178
    [Abstract] [Full Text] [Related]

  • 6. Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays.
    Chan WY, Wo NC, Stoev ST, Cheng LL, Manning M.
    Exp Physiol; 2000 Mar; 85 Spec No():7S-18S. PubMed ID: 10795902
    [Abstract] [Full Text] [Related]

  • 7. Effects of a D-Cys6/L-Cys6 interchange in nonselective and selective vasopressin and oxytocin antagonists.
    Manning M, Cheng LL, Klis WA, Balaspiri L, Olma A, Sawyer WH, Wo NC, Chan WY.
    J Med Chem; 1995 May 12; 38(10):1762-9. PubMed ID: 7752199
    [Abstract] [Full Text] [Related]

  • 8. Solid-phase synthesis of 16 potent (selective and nonselective) in vivo antagonists of oxytocin.
    Manning M, Kruszynski M, Bankowski K, Olma A, Lammek B, Cheng LL, Klis WA, Seto J, Haldar J, Sawyer WH.
    J Med Chem; 1989 Feb 12; 32(2):382-91. PubMed ID: 2913298
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8.
    Pena A, Murat B, Trueba M, Ventura MA, Wo NC, Szeto HH, Cheng LL, Stoev S, Guillon G, Manning M.
    J Med Chem; 2007 Feb 22; 50(4):835-47. PubMed ID: 17300166
    [Abstract] [Full Text] [Related]

  • 10. Design of oxytocin antagonists with prolonged action: potential tocolytic agents for the treatment of preterm labor.
    Chan WY, Hruby VJ, Rockway TW, Hlavacek J.
    J Pharmacol Exp Ther; 1986 Oct 22; 239(1):84-7. PubMed ID: 3761199
    [Abstract] [Full Text] [Related]

  • 11. Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents.
    Manning M, Stoev S, Chini B, Durroux T, Mouillac B, Guillon G.
    Prog Brain Res; 2008 Oct 22; 170():473-512. PubMed ID: 18655903
    [Abstract] [Full Text] [Related]

  • 12. Effects of a single administration of oxytocin or vasopressin and their interactions with two selective receptor antagonists on memory storage in mice.
    Boccia MM, Kopf SR, Baratti CM.
    Neurobiol Learn Mem; 1998 Mar 22; 69(2):136-46. PubMed ID: 9619993
    [Abstract] [Full Text] [Related]

  • 13. Discovery and design of novel vasopressin hypotensive peptide agonists.
    Manning M, Stoev S, Cheng LL, Wo NC, Chan WY.
    J Recept Signal Transduct Res; 1999 Mar 22; 19(1-4):631-44. PubMed ID: 10071789
    [Abstract] [Full Text] [Related]

  • 14. Position three in vasopressin antagonist tolerates conformationally restricted and aromatic amino acid substitutions: a striking contrast with vasopressin agonists.
    Manning M, Cheng LL, Stoev S, Klis W, Nawrocka E, Olma A, Sawyer WH, Wo NC, Chan WY.
    J Pept Sci; 1997 Mar 22; 3(1):31-46. PubMed ID: 9230469
    [Abstract] [Full Text] [Related]

  • 15. Mutual regulation of vasopressin- and oxytocin-induced glucagon secretion in V1b vasopressin receptor knockout mice.
    Fujiwara Y, Hiroyama M, Sanbe A, Yamauchi J, Tsujimoto G, Tanoue A.
    J Endocrinol; 2007 Feb 22; 192(2):361-9. PubMed ID: 17283236
    [Abstract] [Full Text] [Related]

  • 16. Potential use of oxytocin and vasopressin V1a antagonists in the treatment of preterm labour and primary dysmenorrhoea.
    Akerlund M, Melin P, Maggi M.
    Adv Exp Med Biol; 1995 Feb 22; 395():595-600. PubMed ID: 8714023
    [Abstract] [Full Text] [Related]

  • 17. Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4.
    Cheng LL, Stoev S, Manning M, Derick S, Pena A, Mimoun MB, Guillon G.
    J Med Chem; 2004 Apr 22; 47(9):2375-88. PubMed ID: 15084136
    [Abstract] [Full Text] [Related]

  • 18. Pharmacological characterization of V1a vasopressin receptors in the rat cortical collecting duct.
    Ammar A, Roseau S, Butlen D.
    Am J Physiol; 1992 Apr 22; 262(4 Pt 2):F546-53. PubMed ID: 1533099
    [Abstract] [Full Text] [Related]

  • 19. Barusiban suppresses oxytocin-induced preterm labour in non-human primates.
    Reinheimer TM.
    BMC Pregnancy Childbirth; 2007 Jun 01; 7 Suppl 1(Suppl 1):S15. PubMed ID: 17570159
    [Abstract] [Full Text] [Related]

  • 20. Neurohypophyseal hormones protect against pentylenetetrazole-induced seizures in zebrafish: role of oxytocin-like and V1a-like receptor.
    Braida D, Donzelli A, Martucci R, Ponzoni L, Pauletti A, Sala M.
    Peptides; 2012 Oct 01; 37(2):327-33. PubMed ID: 22828174
    [Abstract] [Full Text] [Related]

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