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PUBMED FOR HANDHELDS

Journal Abstract Search


262 related items for PubMed ID: 8632405

  • 1. Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.
    Abreo MA, Lin NH, Garvey DS, Gunn DE, Hettinger AM, Wasicak JT, Pavlik PA, Martin YC, Donnelly-roberts DL, Anderson DJ, Sullivan JP, Williams M, Arneric SP, Holladay MW.
    J Med Chem; 1996 Feb 16; 39(4):817-25. PubMed ID: 8632405
    [Abstract] [Full Text] [Related]

  • 2. (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.
    Arneric SP, Sullivan JP, Briggs CA, Donnelly-Roberts D, Anderson DJ, Raszkiewicz JL, Hughes ML, Cadman ED, Adams P, Garvey DS.
    J Pharmacol Exp Ther; 1994 Jul 16; 270(1):310-8. PubMed ID: 7518514
    [Abstract] [Full Text] [Related]

  • 3. Regulation of human alpha4beta2 neuronal nicotinic acetylcholine receptors by cholinergic channel ligands and second messenger pathways.
    Gopalakrishnan M, Molinari EJ, Sullivan JP.
    Mol Pharmacol; 1997 Sep 16; 52(3):524-34. PubMed ID: 9281615
    [Abstract] [Full Text] [Related]

  • 4. Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them.
    Xiao Y, Fan H, Musachio JL, Wei ZL, Chellappan SK, Kozikowski AP, Kellar KJ.
    Mol Pharmacol; 2006 Oct 16; 70(4):1454-60. PubMed ID: 16857741
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, binding, and modeling studies of new cytisine derivatives, as ligands for neuronal nicotinic acetylcholine receptor subtypes.
    Tasso B, Canu Boido C, Terranova E, Gotti C, Riganti L, Clementi F, Artali R, Bombieri G, Meneghetti F, Sparatore F.
    J Med Chem; 2009 Jul 23; 52(14):4345-57. PubMed ID: 19548687
    [Abstract] [Full Text] [Related]

  • 6. Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.
    Gopalakrishnan M, Monteggia LM, Anderson DJ, Molinari EJ, Piattoni-Kaplan M, Donnelly-Roberts D, Arneric SP, Sullivan JP.
    J Pharmacol Exp Ther; 1996 Jan 23; 276(1):289-97. PubMed ID: 8558445
    [Abstract] [Full Text] [Related]

  • 7. ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors: I. In vitro characterization.
    Donnelly-Roberts DL, Puttfarcken PS, Kuntzweiler TA, Briggs CA, Anderson DJ, Campbell JE, Piattoni-Kaplan M, McKenna DG, Wasicak JT, Holladay MW, Williams M, Arneric SP.
    J Pharmacol Exp Ther; 1998 May 23; 285(2):777-86. PubMed ID: 9580626
    [Abstract] [Full Text] [Related]

  • 8. Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.
    Bunnelle WH, Daanen JF, Ryther KB, Schrimpf MR, Dart MJ, Gelain A, Meyer MD, Frost JM, Anderson DJ, Buckley M, Curzon P, Cao YJ, Puttfarcken P, Searle X, Ji J, Putman CB, Surowy C, Toma L, Barlocco D.
    J Med Chem; 2007 Jul 26; 50(15):3627-44. PubMed ID: 17585748
    [Abstract] [Full Text] [Related]

  • 9. 7-Azaindole derivatives as potential partial nicotinic agonists.
    Stoit AR, den Hartog AP, Mons H, van Schaik S, Barkhuijsen N, Stroomer C, Coolen HK, Reinders JH, Adolfs TJ, van der Neut M, Keizer H, Kruse CG.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):188-93. PubMed ID: 18006307
    [Abstract] [Full Text] [Related]

  • 10. C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists.
    Abin-Carriquiry JA, Voutilainen MH, Barik J, Cassels BK, Iturriaga-Vásquez P, Bermudez I, Durand C, Dajas F, Wonnacott S.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):1-11. PubMed ID: 16563372
    [Abstract] [Full Text] [Related]

  • 11. Interaction of the nicotinic agonist (R,S)-3-pyridyl-1-methyl-2-(3-pyridyl)-azetidine (MPA) with nicotinic acetylcholine receptor subtypes expressed in cell lines and rat cortex.
    Zhang X, Gong ZH, Fasth KJ, Långström B, Nordberg A.
    Neurochem Int; 1998 Apr 24; 32(5-6):435-41. PubMed ID: 9676742
    [Abstract] [Full Text] [Related]

  • 12. Characterization of [3H]ABT-418: a novel cholinergic channel ligand.
    Anderson DJ, Williams M, Pauly JR, Raszkiewicz JL, Campbell JE, Rotert G, Surber B, Thomas SB, Wasicak J, Arneric SP.
    J Pharmacol Exp Ther; 1995 Jun 24; 273(3):1434-41. PubMed ID: 7791118
    [Abstract] [Full Text] [Related]

  • 13. ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties.
    Sullivan JP, Donnelly-Roberts D, Briggs CA, Anderson DJ, Gopalakrishnan M, Xue IC, Piattoni-Kaplan M, Molinari E, Campbell JE, McKenna DG, Gunn DE, Lin NH, Ryther KB, He Y, Holladay MW, Wonnacott S, Williams M, Arneric SP.
    J Pharmacol Exp Ther; 1997 Oct 24; 283(1):235-46. PubMed ID: 9336329
    [Abstract] [Full Text] [Related]

  • 14. Syntheses and evaluation of halogenated cytisine derivatives and of bioisosteric thiocytisine as potent and selective nAChR ligands.
    Imming P, Klaperski P, Stubbs MT, Seitz G, Gündisch D.
    Eur J Med Chem; 2001 Apr 24; 36(4):375-88. PubMed ID: 11461763
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist.
    Sacaan AI, Reid RT, Santori EM, Adams P, Correa LD, Mahaffy LS, Bleicher L, Cosford ND, Stauderman KA, McDonald IA, Rao TS, Lloyd GK.
    J Pharmacol Exp Ther; 1997 Jan 24; 280(1):373-83. PubMed ID: 8996218
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165.
    Sharples CG, Karig G, Simpson GL, Spencer JA, Wright E, Millar NS, Wonnacott S, Gallagher T.
    J Med Chem; 2002 Jul 18; 45(15):3235-45. PubMed ID: 12109907
    [Abstract] [Full Text] [Related]

  • 17. Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors.
    Zwart R, Carbone AL, Moroni M, Bermudez I, Mogg AJ, Folly EA, Broad LM, Williams AC, Zhang D, Ding C, Heinz BA, Sher E.
    Mol Pharmacol; 2008 Jun 18; 73(6):1838-43. PubMed ID: 18367540
    [Abstract] [Full Text] [Related]

  • 18. Effects of chronic nicotine treatment on expression of diverse nicotinic acetylcholine receptor subtypes. I. Dose- and time-dependent effects of nicotine treatment.
    Ke L, Eisenhour CM, Bencherif M, Lukas RJ.
    J Pharmacol Exp Ther; 1998 Aug 18; 286(2):825-40. PubMed ID: 9694939
    [Abstract] [Full Text] [Related]

  • 19. 5-substituted derivatives of 6-halogeno-3-((2-(S)-azetidinyl)methoxy)pyridine and 6-halogeno-3-((2-(S)-pyrrolidinyl)methoxy)pyridine with low picomolar affinity for alpha4beta2 nicotinic acetylcholine receptor and wide range of lipophilicity: potential probes for imaging with positron emission tomography.
    Zhang Y, Pavlova OA, Chefer SI, Hall AW, Kurian V, Brown LL, Kimes AS, Mukhin AG, Horti AG.
    J Med Chem; 2004 May 06; 47(10):2453-65. PubMed ID: 15115389
    [Abstract] [Full Text] [Related]

  • 20. Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist.
    Hansen CP, Jensen AA, Christensen JK, Balle T, Liljefors T, Frølund B.
    J Med Chem; 2008 Dec 11; 51(23):7380-95. PubMed ID: 18989912
    [Abstract] [Full Text] [Related]


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