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2. Tyrosine kinase inhibitors. 11. Soluble analogues of pyrrolo- and pyrazoloquinazolines as epidermal growth factor receptor inhibitors: synthesis, biological evaluation, and modeling of the mode of binding. Palmer BD, Trumpp-Kallmeyer S, Fry DW, Nelson JM, Showalter HD, Denny WA. J Med Chem; 1997 May 09; 40(10):1519-29. PubMed ID: 9154973 [Abstract] [Full Text] [Related]
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5. Tyrosine kinase inhibitors. 13. Structure-activity relationships for soluble 7-substituted 4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidines designed as inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. Thompson AM, Murray DK, Elliott WL, Fry DW, Nelson JA, Showalter HD, Roberts BJ, Vincent PW, Denny WA. J Med Chem; 1997 Nov 21; 40(24):3915-25. PubMed ID: 9397172 [Abstract] [Full Text] [Related]
6. Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor. Bridges AJ, Zhou H, Cody DR, Rewcastle GW, McMichael A, Showalter HD, Fry DW, Kraker AJ, Denny WA. J Med Chem; 1996 Jan 05; 39(1):267-76. PubMed ID: 8568816 [Abstract] [Full Text] [Related]
8. 4-(Phenylamino)pyrrolopyrimidines: potent and selective, ATP site directed inhibitors of the EGF-receptor protein tyrosine kinase. Traxler PM, Furet P, Mett H, Buchdunger E, Meyer T, Lydon N. J Med Chem; 1996 Jun 07; 39(12):2285-92. PubMed ID: 8691423 [Abstract] [Full Text] [Related]
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17. Inhibition of growth factor-mediated tyrosine phosphorylation in vascular smooth muscle by PD 089828, a new synthetic protein tyrosine kinase inhibitor. Dahring TK, Lu GH, Hamby JM, Batley BL, Kraker AJ, Panek RL. J Pharmacol Exp Ther; 1997 Jun 06; 281(3):1446-56. PubMed ID: 9190882 [Abstract] [Full Text] [Related]