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Journal Abstract Search

122 related items for PubMed ID: 8632694

  • 1. Enhancement effect of O6-fluorobenzylguanines on chloroethylnitrosourea cytotoxicity in tumor cells.
    Mineura K, Fukuchi M, Kowada M, Hitomi K, Terashima I, Kohda K.
    Life Sci; 1996; 58(19):PL303-8. PubMed ID: 8632694
    [Abstract] [Full Text] [Related]

  • 2. Differential inactivation of O6-methylguanine-DNA methyltransferase activity by O6-arylmethylguanines.
    Mineura K, Fukuchi M, Kowada M, Terashima I, Kohda K.
    Int J Cancer; 1995 Sep 27; 63(1):148-51. PubMed ID: 7558444
    [Abstract] [Full Text] [Related]

  • 3. [Study on potentiation of nitrosourea-cytotoxicity by DNA repair enzyme inhibitors in human brain tumor cells].
    Fukuchi M, Mineura K, Kowada M, Terashima I, Kohda K.
    No To Shinkei; 1997 Jun 27; 49(6):521-8. PubMed ID: 9198092
    [Abstract] [Full Text] [Related]

  • 4. Enhancing effect of O6-alkylguanine derivatives on chloroethylnitrosourea cytotoxicity toward tumor cells.
    Mineura K, Izumi I, Watanabe K, Kowada M, Kohda K, Koyama K, Terashima I, Ikenaga M.
    Int J Cancer; 1994 Sep 01; 58(5):706-12. PubMed ID: 8077057
    [Abstract] [Full Text] [Related]

  • 5. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
    Chen JM, Zhang YP, Sui JL, Moschel RC, Ikenaga M.
    Anticancer Res; 1993 Sep 01; 13(3):801-5. PubMed ID: 8317915
    [Abstract] [Full Text] [Related]

  • 6. Potentiation of the cytotoxicity of chloroethylnitrosourea by O6-arylmethylguanines.
    Kohda K, Terashima I, Koyama K, Watanabe K, Mineura K.
    Biol Pharm Bull; 1995 Mar 01; 18(3):424-30. PubMed ID: 7550096
    [Abstract] [Full Text] [Related]

  • 7. Depletion of O6-methylguanine-DNA methyltransferase and potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea antitumor activity by O6-benzylguanine in vitro.
    Chen JM, Zhang YP, Moschel RC, Ikenaga M.
    Carcinogenesis; 1993 May 01; 14(5):1057-60. PubMed ID: 8504466
    [Abstract] [Full Text] [Related]

  • 8. Potential of O6-methylguanine or O6-benzylguanine in the enhancement of chloroethylnitrosourea cytotoxicity on brain tumours.
    Mineura K, Izumi I, Watanabe K, Kowada M, Kohda K, Ikenaga M.
    Acta Neurochir (Wien); 1994 May 01; 128(1-4):13-20. PubMed ID: 7847129
    [Abstract] [Full Text] [Related]

  • 9. Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity.
    Marathi UK, Dolan ME, Erickson LC.
    Cancer Res; 1994 Aug 15; 54(16):4371-5. PubMed ID: 8044784
    [Abstract] [Full Text] [Related]

  • 10. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    Maze R, Kurpad C, Pegg AE, Erickson LC, Williams DA.
    J Pharmacol Exp Ther; 1999 Sep 15; 290(3):1467-74. PubMed ID: 10454526
    [Abstract] [Full Text] [Related]

  • 11. O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
    Phillips WP, Willson JK, Markowitz SD, Zborowska E, Zaidi NH, Liu L, Gordon NH, Gerson SL.
    Cancer Res; 1997 Nov 01; 57(21):4817-23. PubMed ID: 9354444
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of human O6-alkylguanine-DNA alkyltransferase and potentiation of the cytotoxicity of chloroethylnitrosourea by 4(6)-(benzyloxy)-2,6(4)-diamino-5-(nitro or nitroso)pyrimidine derivatives and analogues.
    Terashima I, Kohda K.
    J Med Chem; 1998 Feb 12; 41(4):503-8. PubMed ID: 9484500
    [Abstract] [Full Text] [Related]

  • 13. O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo.
    Takahashi M, Mineura K, Watanabe K, Kohda K.
    Acta Oncol; 2000 Feb 12; 39(1):89-95. PubMed ID: 10752660
    [Abstract] [Full Text] [Related]

  • 14. Inactivation of O6-methylguanine-DNA methyltransferase and sensitization of human tumor cells to killing by chloroethylnitrosourea by O6-methylguanine as a free base.
    Yarosh DB, Hurst-Calderone S, Babich MA, Day RS.
    Cancer Res; 1986 Apr 12; 46(4 Pt 1):1663-8. PubMed ID: 3948156
    [Abstract] [Full Text] [Related]

  • 15. Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
    Dolan ME, Pegg AE, Hora NK, Erickson LC.
    Cancer Res; 1988 Jul 01; 48(13):3603-6. PubMed ID: 2837318
    [Abstract] [Full Text] [Related]

  • 16. Increased killing of prostate, breast, colon, and lung tumor cells by the combination of inactivators of O6-alkylguanine-DNA alkyltransferase and N,N'-bis(2-chloroethyl)-N-nitrosourea.
    Pegg AE, Swenn K, Chae MY, Dolan ME, Moschel RC.
    Biochem Pharmacol; 1995 Oct 12; 50(8):1141-8. PubMed ID: 7488227
    [Abstract] [Full Text] [Related]

  • 17. Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
    Dolan ME, Moschel RC, Pegg AE.
    Proc Natl Acad Sci U S A; 1990 Jul 12; 87(14):5368-72. PubMed ID: 2164681
    [Abstract] [Full Text] [Related]

  • 18. Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.
    Cussac C, Rapp M, Mounetou E, Madelmont JC, Maurizis JC, Godeneche D, Dupuy JM, Sauzieres J, Baudry JP, Veyre A.
    J Pharmacol Exp Ther; 1994 Dec 12; 271(3):1353-8. PubMed ID: 7996446
    [Abstract] [Full Text] [Related]

  • 19. Prolonged depletion of O6-methylguanine DNA methyltransferase activity following exposure to O6-benzylguanine with or without streptozotocin enhances 1,3-bis(2-chloroethyl)-1-nitrosourea sensitivity in vitro.
    Marathi UK, Kroes RA, Dolan ME, Erickson LC.
    Cancer Res; 1993 Sep 15; 53(18):4281-6. PubMed ID: 8364924
    [Abstract] [Full Text] [Related]

  • 20. Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.
    Passagne I, Evrard A, Winum JY, Depeille P, Cuq P, Montero JL, Cupissol D, Vian L.
    J Pharmacol Exp Ther; 2003 Nov 15; 307(2):816-23. PubMed ID: 12970393
    [Abstract] [Full Text] [Related]

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