These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

215 related items for PubMed ID: 8636149

  • 1. Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin. Evidence that IRS-1 phosphorylation is not sufficient for normal insulin action.
    Krook A, Moller DE, Dib K, O'Rahilly S.
    J Biol Chem; 1996 Mar 22; 271(12):7134-40. PubMed ID: 8636149
    [Abstract] [Full Text] [Related]

  • 2. Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects.
    Krook A, Whitehead JP, Dobson SP, Griffiths MR, Ouwens M, Baker C, Hayward AC, Sen SK, Maassen JA, Siddle K, Tavaré JM, O'Rahilly S.
    J Biol Chem; 1997 Nov 28; 272(48):30208-14. PubMed ID: 9374504
    [Abstract] [Full Text] [Related]

  • 3. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
    Ando A, Momomura K, Tobe K, Yamamoto-Honda R, Sakura H, Tamori Y, Kaburagi Y, Koshio O, Akanuma Y, Yazaki Y.
    J Biol Chem; 1992 Jun 25; 267(18):12788-96. PubMed ID: 1618780
    [Abstract] [Full Text] [Related]

  • 4. Signal transduction pathways from insulin receptors to Ras. Analysis by mutant insulin receptors.
    Yonezawa K, Ando A, Kaburagi Y, Yamamoto-Honda R, Kitamura T, Hara K, Nakafuku M, Okabayashi Y, Kadowaki T, Kaziro Y.
    J Biol Chem; 1994 Feb 11; 269(6):4634-40. PubMed ID: 7508445
    [Abstract] [Full Text] [Related]

  • 5. Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif.
    Chen D, Van Horn DJ, White MF, Backer JM.
    Mol Cell Biol; 1995 Sep 11; 15(9):4711-7. PubMed ID: 7651388
    [Abstract] [Full Text] [Related]

  • 6. Expression and function of IRS-1 in insulin signal transmission.
    Sun XJ, Miralpeix M, Myers MG, Glasheen EM, Backer JM, Kahn CR, White MF.
    J Biol Chem; 1992 Nov 05; 267(31):22662-72. PubMed ID: 1385403
    [Abstract] [Full Text] [Related]

  • 7.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 8. Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2.
    Tobe K, Matuoka K, Tamemoto H, Ueki K, Kaburagi Y, Asai S, Noguchi T, Matsuda M, Tanaka S, Hattori S.
    J Biol Chem; 1993 May 25; 268(15):11167-71. PubMed ID: 8388384
    [Abstract] [Full Text] [Related]

  • 9. The role of the NPXY motif in the insulin receptor in tyrosine phosphorylation of insulin receptor substrate-1 and Shc.
    Kaburagi Y, Yamamoto-Honda R, Tobe K, Ueki K, Yachi M, Akanuma Y, Stephens RM, Kaplan D, Yazaki Y, Kadowaki T.
    Endocrinology; 1995 Aug 25; 136(8):3437-43. PubMed ID: 7543044
    [Abstract] [Full Text] [Related]

  • 10. Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase.
    Fujioka T, Kim JH, Adachi H, Saito K, Tsujimoto M, Yokoyama S, Ui M.
    Eur J Biochem; 2001 Aug 25; 268(15):4158-68. PubMed ID: 11488908
    [Abstract] [Full Text] [Related]

  • 11. Site-directed mutagenesis of the juxtamembrane domain of the human insulin receptor.
    Kaburagi Y, Momomura K, Yamamoto-Honda R, Tobe K, Tamori Y, Sakura H, Akanuma Y, Yazaki Y, Kadowaki T.
    J Biol Chem; 1993 Aug 05; 268(22):16610-22. PubMed ID: 8393870
    [Abstract] [Full Text] [Related]

  • 12. Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation.
    Berhanu P, Anderson C, Hickman M, Ciaraldi TP.
    J Biol Chem; 1997 Sep 05; 272(36):22884-90. PubMed ID: 9278451
    [Abstract] [Full Text] [Related]

  • 13. Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling.
    Liberman Z, Eldar-Finkelman H.
    J Biol Chem; 2005 Feb 11; 280(6):4422-8. PubMed ID: 15574412
    [Abstract] [Full Text] [Related]

  • 14. Vanadyl sulfate-stimulated glycogen synthesis is associated with activation of phosphatidylinositol 3-kinase and is independent of insulin receptor tyrosine phosphorylation.
    Pandey SK, Anand-Srivastava MB, Srivastava AK.
    Biochemistry; 1998 May 12; 37(19):7006-14. PubMed ID: 9578588
    [Abstract] [Full Text] [Related]

  • 15. The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies.
    Wilden PA, Siddle K, Haring E, Backer JM, White MF, Kahn CR.
    J Biol Chem; 1992 Jul 05; 267(19):13719-27. PubMed ID: 1320027
    [Abstract] [Full Text] [Related]

  • 16. Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.
    De Fea K, Roth RA.
    Biochemistry; 1997 Oct 21; 36(42):12939-47. PubMed ID: 9335553
    [Abstract] [Full Text] [Related]

  • 17. Serine residues 1177/78/82 of the insulin receptor are required for substrate phosphorylation but not autophosphorylation.
    Bossenmaier B, Strack V, Stoyanov B, Krützfeldt J, Beck A, Lehmann R, Kellerer M, Klein H, Ullrich A, Lammers R, Häring HU.
    Diabetes; 2000 Jun 21; 49(6):889-95. PubMed ID: 10866039
    [Abstract] [Full Text] [Related]

  • 18. Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells.
    Ahn J, Rosen OM, Donner DB.
    J Biol Chem; 1993 Aug 05; 268(22):16839-44. PubMed ID: 8393875
    [Abstract] [Full Text] [Related]

  • 19. Normal insulin receptor substrate-1 phosphorylation in autophosphorylation-defective truncated insulin receptor. Evidence that phosphorylation of substrates might be sufficient for certain biological effects evoked by insulin.
    Yamamoto-Honda R, Kadowaki T, Momomura K, Tobe K, Tamori Y, Shibasaki Y, Mori Y, Kaburagi Y, Koshio O, Akanuma Y.
    J Biol Chem; 1993 Aug 05; 268(22):16859-65. PubMed ID: 8344965
    [Abstract] [Full Text] [Related]

  • 20. Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
    Wilden PA, Kahn CR, Siddle K, White MF.
    J Biol Chem; 1992 Aug 15; 267(23):16660-8. PubMed ID: 1322912
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 11.