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Journal Abstract Search

759 related items for PubMed ID: 8645011

  • 1. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.
    Keller RK, Zhao Z, Chambers C, Ness GC.
    Arch Biochem Biophys; 1996 Apr 15; 328(2):324-30. PubMed ID: 8645011
    [Abstract] [Full Text] [Related]

  • 2. Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase.
    Ness GC, Zhao Z, Keller RK.
    Arch Biochem Biophys; 1994 Jun 15; 311(2):277-85. PubMed ID: 7911291
    [Abstract] [Full Text] [Related]

  • 3. Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro.
    Correll CC, Edwards PA.
    J Biol Chem; 1994 Jan 07; 269(1):633-8. PubMed ID: 8276863
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level.
    Peffley DM, Gayen AK.
    Arch Biochem Biophys; 1997 Jan 15; 337(2):251-60. PubMed ID: 9016820
    [Abstract] [Full Text] [Related]

  • 5. HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells.
    Petras SF, Lindsey S, Harwood HJ.
    J Lipid Res; 1999 Jan 15; 40(1):24-38. PubMed ID: 9869647
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
    Flint OP, Masters BA, Gregg RE, Durham SK.
    Toxicol Appl Pharmacol; 1997 Jul 15; 145(1):91-8. PubMed ID: 9221828
    [Abstract] [Full Text] [Related]

  • 7. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by sterols and nonsterols in rat liver.
    Ness GC, Eales S, Lopez D, Zhao Z.
    Arch Biochem Biophys; 1994 Feb 01; 308(2):420-5. PubMed ID: 8109970
    [Abstract] [Full Text] [Related]

  • 8. Compensatory responses to inhibition of hepatic squalene synthase.
    Lopez D, Chambers CM, Keller RK, Ness GC.
    Arch Biochem Biophys; 1998 Mar 15; 351(2):159-66. PubMed ID: 9514656
    [Abstract] [Full Text] [Related]

  • 9. Inhibitors of cholesterol biosynthesis increase hepatic low-density lipoprotein receptor protein degradation.
    Ness GC, Zhao Z, Lopez D.
    Arch Biochem Biophys; 1996 Jan 15; 325(2):242-8. PubMed ID: 8561503
    [Abstract] [Full Text] [Related]

  • 10. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors unmask cryptic regulatory mechanisms.
    Lopez D, Chambers CM, Ness GC.
    Arch Biochem Biophys; 1997 Jul 01; 343(1):118-22. PubMed ID: 9210653
    [Abstract] [Full Text] [Related]

  • 11. Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase.
    Meigs TE, Simoni RD.
    Arch Biochem Biophys; 1997 Sep 01; 345(1):1-9. PubMed ID: 9281305
    [Abstract] [Full Text] [Related]

  • 12. Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Correll CC, Ng L, Edwards PA.
    J Biol Chem; 1994 Jul 01; 269(26):17390-3. PubMed ID: 8021239
    [Abstract] [Full Text] [Related]

  • 13. Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A.
    Vaidya S, Bostedor R, Kurtz MM, Bergstrom JD, Bansal VS.
    Arch Biochem Biophys; 1998 Jul 01; 355(1):84-92. PubMed ID: 9647670
    [Abstract] [Full Text] [Related]

  • 14. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo.
    Meigs TE, Roseman DS, Simoni RD.
    J Biol Chem; 1996 Apr 05; 271(14):7916-22. PubMed ID: 8626470
    [Abstract] [Full Text] [Related]

  • 15. Effects of 15-oxa-32-vinyl-lanost-8-ene-3 beta,32 diol on the expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and low density lipoprotein receptor in rat liver.
    Ness GC, Lopez D, Chambers CM, Zhao Z, Beach DL, Ko SS, Trzaskos JM.
    Arch Biochem Biophys; 1998 Sep 15; 357(2):259-64. PubMed ID: 9735166
    [Abstract] [Full Text] [Related]

  • 16. Characterization and regulation of HMG-CoA reductase during a cycle of juvenile hormone synthesis.
    Feyereisen R, Farnsworth DE.
    Mol Cell Endocrinol; 1987 Oct 15; 53(3):227-38. PubMed ID: 3666299
    [Abstract] [Full Text] [Related]

  • 17. RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase.
    Amin D, Rutledge RZ, Needle SN, Galczenski HF, Neuenschwander K, Scotese AC, Maguire MP, Bush RC, Hele DJ, Bilder GE, Perrone MH.
    J Pharmacol Exp Ther; 1997 May 15; 281(2):746-52. PubMed ID: 9152381
    [Abstract] [Full Text] [Related]

  • 18. Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase.
    Kita T, Brown MS, Goldstein JL.
    J Clin Invest; 1980 Nov 15; 66(5):1094-100. PubMed ID: 6903572
    [Abstract] [Full Text] [Related]

  • 19. Regulation of cholesterol 7 alpha-hydroxylase expression by sterols in primary rat hepatocyte cultures.
    Doerner KC, Gurley EC, Vlahcevic ZR, Hylemon PB.
    J Lipid Res; 1995 Jun 15; 36(6):1168-77. PubMed ID: 7665995
    [Abstract] [Full Text] [Related]

  • 20. In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone.
    Beg ZH, Stonik JA, Brewer HB.
    Proc Natl Acad Sci U S A; 1984 Dec 15; 81(23):7293-7. PubMed ID: 6594693
    [Abstract] [Full Text] [Related]

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