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Journal Abstract Search

121 related items for PubMed ID: 8648601

  • 1. Lipophilic, acid-stable, adenosine deaminase-activated anti-HIV prodrugs for central nervous system delivery. 3. 6-Amino prodrugs of 2'-beta-fluoro-2',3'-dideoxyinosine.
    Driscoll JS, Siddiqui MA, Ford H, Kelley JA, Roth JS, Mitsuya H, Tanaka M, Marquez VE.
    J Med Chem; 1996 Apr 12; 39(8):1619-25. PubMed ID: 8648601
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  • 3. In vitro and in vivo evaluation of 6-azido-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosylpurine and N6-methyl-2',3'-dideoxy-2'-fluoro-beta-D-arabinofuranosyladenine as prodrugs of the anti-HIV nucleosides 2'-F-ara-ddA and 2'-F-ara-ddI.
    Koudriakova T, Manouilov KK, Shanmuganathan K, Kotra LP, Boudinot FD, Cretton-Scott E, Sommadossi JP, Schinazi RF, Chu CK.
    J Med Chem; 1996 Nov 08; 39(23):4676-81. PubMed ID: 8917656
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  • 5. Role of altered metabolism in dideoxynucleoside pharmacokinetics. Studies of 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.
    Singhal D, Morgan ME, Anderson BD.
    Drug Metab Dispos; 1996 Oct 08; 24(10):1155-61. PubMed ID: 8894519
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  • 7. cycloSal-Pronucleotides of 2'-fluoro-ara- and 2'-fluoro-ribo-2',3'- dideoxyadenosine as a strategy to bypass a metabolic blockade.
    Meier C, Knispel T, Marquez VE, Siddiqui MA, De Clercq E, Balzarini J.
    J Med Chem; 1999 May 06; 42(9):1615-24. PubMed ID: 10229630
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  • 9. Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs.
    Barchi JJ, Marquez VE, Driscoll JS, Ford H, Mitsuya H, Shirasaka T, Aoki S, Kelley JA.
    J Med Chem; 1991 May 06; 34(5):1647-55. PubMed ID: 2033591
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  • 13. Molecular structures of two new anti-HIV nucleoside analogs: 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine and 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)hypoxanthine.
    Liaw YC, Gao YG, Marquez VE, Wang AH.
    Nucleic Acids Res; 1992 Feb 11; 20(3):459-65. PubMed ID: 1741280
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  • 16. 2'-Fluoro-2',3'-dideoxyarabinosyladenine: a metabolically stable analogue of the antiretroviral agent 2',3'-dideoxyadenosine.
    Masood R, Ahluwalia GS, Cooney DA, Fridland A, Marquez VE, Driscoll JS, Hao Z, Mitsuya H, Perno CF, Broder S.
    Mol Pharmacol; 1990 Apr 11; 37(4):590-6. PubMed ID: 2109183
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  • 17. Enhanced brain delivery of an anti-HIV nucleoside 2'-F-ara-ddI by xanthine oxidase mediated biotransformation.
    Shanmuganathan K, Koudriakova T, Nampalli S, Du J, Gallo JM, Schinazi RF, Chu CK.
    J Med Chem; 1994 Mar 18; 37(6):821-7. PubMed ID: 8145233
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