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Journal Abstract Search

93 related items for PubMed ID: 8651910

  • 21. Effects of mutations involving cysteine residues distal to the S281HCC motif at the C-terminus on the functional characteristics of a truncated ectodomain-only thyrotropin receptor anchored on glycosylphosphatidyl-inositol.
    Ho SC, Goh SS, Li S, Khoo DH, Paterson M.
    Thyroid; 2008 Dec; 18(12):1313-9. PubMed ID: 18976165
    [Abstract] [Full Text] [Related]

  • 22. Further studies of amino acids (268-304) in thyrotropin (TSH)--lutropin/chorionic gonadotropin (LH/CG) receptor chimeras: cysteine-301 is important in TSH binding and receptor tertiary structure.
    Akamizu T, Inoue D, Kosugi S, Kohn LD, Mori T.
    Thyroid; 1994 Dec; 4(1):43-8. PubMed ID: 8054860
    [Abstract] [Full Text] [Related]

  • 23. Mutations of thyrotropin receptor isolated from thyroid autonomous functioning adenomas confer TSH-independent growth to thyroid cells.
    Porcellini A, Ruggiano G, Pannain S, Ciullo I, Amabile G, Fenzi G, Avvedimento EV.
    Oncogene; 1997 Aug 14; 15(7):781-9. PubMed ID: 9266964
    [Abstract] [Full Text] [Related]

  • 24. Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships.
    Szkudlinski MW, Fremont V, Ronin C, Weintraub BD.
    Physiol Rev; 2002 Apr 14; 82(2):473-502. PubMed ID: 11917095
    [Abstract] [Full Text] [Related]

  • 25. Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies.
    Kosugi S, Ban T, Akamizu T, Kohn LD.
    Biochem Biophys Res Commun; 1992 Dec 30; 189(3):1754-62. PubMed ID: 1336379
    [Abstract] [Full Text] [Related]

  • 26. The third exoplasmic loop of the thyrotropin receptor is partially involved in signal transduction.
    Kosugi S, Mori T.
    FEBS Lett; 1994 Jul 25; 349(1):89-92. PubMed ID: 8045308
    [Abstract] [Full Text] [Related]

  • 27. Thyroid stimulating autoantibody M22 mimics TSH binding to the TSH receptor leucine rich domain: a comparative structural study of protein-protein interactions.
    Núñez Miguel R, Sanders J, Chirgadze DY, Furmaniak J, Rees Smith B.
    J Mol Endocrinol; 2009 May 25; 42(5):381-95. PubMed ID: 19221175
    [Abstract] [Full Text] [Related]

  • 28. Oncogenic potential of a mutant human thyrotropin receptor expressed in FRTL-5 cells.
    Fournes B, Monier R, Michiels F, Milgrom E, Misrahi M, Feunteun J.
    Oncogene; 1998 Feb 26; 16(8):985-90. PubMed ID: 9519872
    [Abstract] [Full Text] [Related]

  • 29. Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro.
    Mueller S, Jaeschke H, Paschke R.
    Methods Enzymol; 2010 Feb 26; 485():421-36. PubMed ID: 21050930
    [Abstract] [Full Text] [Related]

  • 30. The first cytoplasmic loop of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist-induced adenylate cyclase activation.
    Kosugi S, Mori T.
    FEBS Lett; 1994 Mar 21; 341(2-3):162-6. PubMed ID: 8137933
    [Abstract] [Full Text] [Related]

  • 31. Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.
    Smits G, Govaerts C, Nubourgh I, Pardo L, Vassart G, Costagliola S.
    Mol Endocrinol; 2002 Apr 21; 16(4):722-35. PubMed ID: 11923469
    [Abstract] [Full Text] [Related]

  • 32. Chimeric studies of the extracellular domain of the rat thyrotropin (TSH) receptor: amino acids (268-304) in the TSH receptor are involved in ligand high affinity binding, but not in TSH receptor-specific signal transduction.
    Akamizu T, Inoue D, Kosugi S, Ban T, Kohn LD, Imura H, Mori T.
    Endocr J; 1993 Jun 21; 40(3):363-72. PubMed ID: 7920890
    [Abstract] [Full Text] [Related]

  • 33. Thyrotropin Receptor: Allosteric Modulators Illuminate Intramolecular Signaling Mechanisms at the Interface of Ecto- and Transmembrane Domain.
    Marcinkowski P, Kreuchwig A, Mendieta S, Hoyer I, Witte F, Furkert J, Rutz C, Lentz D, Krause G, Schülein R.
    Mol Pharmacol; 2019 Oct 21; 96(4):452-462. PubMed ID: 31399504
    [Abstract] [Full Text] [Related]

  • 34. Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.
    Agretti P, De Marco G, Collecchi P, Chiovato L, Vitti P, Pinchera A, Tonacchera M.
    Eur J Biochem; 2003 Sep 21; 270(18):3839-47. PubMed ID: 12950268
    [Abstract] [Full Text] [Related]

  • 35. Aspartate-474 in the first exoplasmic loop of the thyrotropin receptor is crucial for receptor activation.
    Kosugi S, Matsuda A, Hai N, Aoki N, Sugawa H, Mori T.
    FEBS Lett; 1997 Apr 07; 406(1-2):139-41. PubMed ID: 9109404
    [Abstract] [Full Text] [Related]

  • 36. Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor.
    Claus M, Neumann S, Kleinau G, Krause G, Paschke R.
    J Mol Med (Berl); 2006 Nov 07; 84(11):943-54. PubMed ID: 16955277
    [Abstract] [Full Text] [Related]

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  • 38. A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.
    Claeysen S, Govaerts C, Lefort A, Van Sande J, Costagliola S, Pardo L, Vassart G.
    FEBS Lett; 2002 Apr 24; 517(1-3):195-200. PubMed ID: 12062436
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  • 40. New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.
    Biebermann H, Winkler F, Handke D, Teichmann A, Gerling B, Cameron F, Eichhorst J, Grüters A, Wiesner B, Kühnen P, Krude H, Kleinau G.
    J Clin Endocrinol Metab; 2012 Feb 24; 97(2):E228-32. PubMed ID: 22112806
    [Abstract] [Full Text] [Related]

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