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245 related items for PubMed ID: 8662591

  • 1. Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation.
    Gerhartz C, Heesel B, Sasse J, Hemmann U, Landgraf C, Schneider-Mergener J, Horn F, Heinrich PC, Graeve L.
    J Biol Chem; 1996 May 31; 271(22):12991-8. PubMed ID: 8662591
    [Abstract] [Full Text] [Related]

  • 2. Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation.
    Hemmann U, Gerhartz C, Heesel B, Sasse J, Kurapkat G, Grötzinger J, Wollmer A, Zhong Z, Darnell JE, Graeve L, Heinrich PC, Horn F.
    J Biol Chem; 1996 May 31; 271(22):12999-3007. PubMed ID: 8662795
    [Abstract] [Full Text] [Related]

  • 3. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F, Gendo C, Eck M, Schmitz J, Grimm C, Anhuf D, Kerr IM, Heinrich PC.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [Abstract] [Full Text] [Related]

  • 4. Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.
    Lütticken C, Wegenka UM, Yuan J, Buschmann J, Schindler C, Ziemiecki A, Harpur AG, Wilks AF, Yasukawa K, Taga T.
    Science; 1994 Jan 07; 263(5143):89-92. PubMed ID: 8272872
    [Abstract] [Full Text] [Related]

  • 5. The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.
    Wegenka UM, Lütticken C, Buschmann J, Yuan J, Lottspeich F, Müller-Esterl W, Schindler C, Roeb E, Heinrich PC, Horn F.
    Mol Cell Biol; 1994 May 07; 14(5):3186-96. PubMed ID: 8164674
    [Abstract] [Full Text] [Related]

  • 6. The amino acid residues immediately carboxyl-terminal to the tyrosine phosphorylation site contribute to interleukin 6-specific activation of signal transducer and activator of transcription 3.
    Inoue M, Minami M, Matsumoto M, Kishimoto T, Akira S.
    J Biol Chem; 1997 Apr 04; 272(14):9550-5. PubMed ID: 9083098
    [Abstract] [Full Text] [Related]

  • 7. Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain.
    Weber-Nordt RM, Riley JK, Greenlund AC, Moore KW, Darnell JE, Schreiber RD.
    J Biol Chem; 1996 Nov 01; 271(44):27954-61. PubMed ID: 8910398
    [Abstract] [Full Text] [Related]

  • 8. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.
    Dahmen H, Horsten U, Küster A, Jacques Y, Minvielle S, Kerr IM, Ciliberto G, Paonessa G, Heinrich PC, Müller-Newen G.
    Biochem J; 1998 May 01; 331 ( Pt 3)(Pt 3):695-702. PubMed ID: 9560294
    [Abstract] [Full Text] [Related]

  • 9. Signal transducer and activator of transcription STAT3 plays a major role in gp130-mediated acute phase protein gene activation.
    May P, Schniertshauer U, Gerhartz C, Horn F, Heinrich PC.
    Acta Biochim Pol; 2003 May 01; 50(3):595-601. PubMed ID: 14515142
    [Abstract] [Full Text] [Related]

  • 10. The cytoplasmic tyrosine motifs in full-length glycoprotein 130 have different roles in IL-6 signal transduction.
    Schmitz J, Dahmen H, Grimm C, Gendo C, Müller-Newen G, Heinrich PC, Schaper F.
    J Immunol; 2000 Jan 15; 164(2):848-54. PubMed ID: 10623831
    [Abstract] [Full Text] [Related]

  • 11. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L, Maassen BG, Radtke S, Behrmann I, Schaper F, Heinrich PC, Graeve L, Gatsios P.
    FEBS Lett; 2000 Jul 28; 478(1-2):100-4. PubMed ID: 10922477
    [Abstract] [Full Text] [Related]

  • 12. The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation.
    de Koning JP, Dong F, Smith L, Schelen AM, Barge RM, van der Plas DC, Hoefsloot LH, Löwenberg B, Touw IP.
    Blood; 1996 Feb 15; 87(4):1335-42. PubMed ID: 8608222
    [Abstract] [Full Text] [Related]

  • 13. Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells.
    Kim H, Hawley TS, Hawley RG, Baumann H.
    Mol Cell Biol; 1998 Mar 15; 18(3):1525-33. PubMed ID: 9488469
    [Abstract] [Full Text] [Related]

  • 14. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.
    Heinrich PC, Behrmann I, Müller-Newen G, Schaper F, Graeve L.
    Biochem J; 1998 Sep 01; 334 ( Pt 2)(Pt 2):297-314. PubMed ID: 9716487
    [Abstract] [Full Text] [Related]

  • 15. The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway.
    Abe K, Hirai M, Mizuno K, Higashi N, Sekimoto T, Miki T, Hirano T, Nakajima K.
    Oncogene; 2001 Jun 14; 20(27):3464-74. PubMed ID: 11429693
    [Abstract] [Full Text] [Related]

  • 16. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
    Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C.
    Mol Endocrinol; 1996 May 14; 10(5):519-33. PubMed ID: 8732683
    [Abstract] [Full Text] [Related]

  • 17. The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130.
    Terstegen L, Gatsios P, Bode JG, Schaper F, Heinrich PC, Graeve L.
    J Biol Chem; 2000 Jun 23; 275(25):18810-7. PubMed ID: 10764798
    [Abstract] [Full Text] [Related]

  • 18. Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway.
    Thiel S, Behrmann I, Dittrich E, Muys L, Tavernier J, Wijdenes J, Heinrich PC, Graeve L.
    Biochem J; 1998 Feb 15; 330 ( Pt 1)(Pt 1):47-54. PubMed ID: 9461489
    [Abstract] [Full Text] [Related]

  • 19. Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor alpha chain.
    van der Plas DC, Smiers F, Pouwels K, Hoefsloot LH, Löwenberg B, Touw IP.
    Leukemia; 1996 Aug 15; 10(8):1317-25. PubMed ID: 8709637
    [Abstract] [Full Text] [Related]

  • 20. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.
    Akira S, Nishio Y, Inoue M, Wang XJ, Wei S, Matsusaka T, Yoshida K, Sudo T, Naruto M, Kishimoto T.
    Cell; 1994 Apr 08; 77(1):63-71. PubMed ID: 7512451
    [Abstract] [Full Text] [Related]

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