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132 related items for PubMed ID: 8662889

  • 1. Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility.
    Ponzetto C, Zhen Z, Audero E, Maina F, Bardelli A, Basile ML, Giordano S, Narsimhan R, Comoglio P.
    J Biol Chem; 1996 Jun 14; 271(24):14119-23. PubMed ID: 8662889
    [Abstract] [Full Text] [Related]

  • 2. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family.
    Ponzetto C, Bardelli A, Zhen Z, Maina F, dalla Zonca P, Giordano S, Graziani A, Panayotou G, Comoglio PM.
    Cell; 1994 Apr 22; 77(2):261-71. PubMed ID: 7513258
    [Abstract] [Full Text] [Related]

  • 3. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases.
    Lock LS, Royal I, Naujokas MA, Park M.
    J Biol Chem; 2000 Oct 06; 275(40):31536-45. PubMed ID: 10913131
    [Abstract] [Full Text] [Related]

  • 4. Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2.
    Corbalan-Garcia S, Yang SS, Degenhardt KR, Bar-Sagi D.
    Mol Cell Biol; 1996 Oct 06; 16(10):5674-82. PubMed ID: 8816480
    [Abstract] [Full Text] [Related]

  • 5. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V, Scott RP, Ibáñez CF.
    J Biol Chem; 2000 Dec 15; 275(50):39159-66. PubMed ID: 10995764
    [Abstract] [Full Text] [Related]

  • 6. Grb2 binding to the different isoforms of Ret tyrosine kinase.
    Alberti L, Borrello MG, Ghizzoni S, Torriti F, Rizzetti MG, Pierotti MA.
    Oncogene; 1998 Sep 03; 17(9):1079-87. PubMed ID: 9764818
    [Abstract] [Full Text] [Related]

  • 7. Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain.
    Dikic I, Batzer AG, Blaikie P, Obermeier A, Ullrich A, Schlessinger J, Margolis B.
    J Biol Chem; 1995 Jun 23; 270(25):15125-9. PubMed ID: 7541035
    [Abstract] [Full Text] [Related]

  • 8. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
    van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.
    Curr Biol; 1995 Apr 01; 5(4):404-12. PubMed ID: 7542991
    [Abstract] [Full Text] [Related]

  • 9. Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase.
    Fournier TM, Kamikura D, Teng K, Park M.
    J Biol Chem; 1996 Sep 06; 271(36):22211-7. PubMed ID: 8703035
    [Abstract] [Full Text] [Related]

  • 10. Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.
    VanderKuur J, Allevato G, Billestrup N, Norstedt G, Carter-Su C.
    J Biol Chem; 1995 Mar 31; 270(13):7587-93. PubMed ID: 7535773
    [Abstract] [Full Text] [Related]

  • 11. Differential requirement of Tyr1062 multidocking site by RET isoforms to promote neural cell scattering and epithelial cell branching.
    Degl'Innocenti D, Arighi E, Popsueva A, Sangregorio R, Alberti L, Rizzetti MG, Ferrario C, Sariola H, Pierotti MA, Borrello MG.
    Oncogene; 2004 Sep 23; 23(44):7297-309. PubMed ID: 15326489
    [Abstract] [Full Text] [Related]

  • 12. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S, Ito T, Wands JR.
    J Biol Chem; 1996 Jun 14; 271(24):14610-6. PubMed ID: 8662827
    [Abstract] [Full Text] [Related]

  • 13. Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.
    Gotoh N, Tojo A, Muroya K, Hashimoto Y, Hattori S, Nakamura S, Takenawa T, Yazaki Y, Shibuya M.
    Proc Natl Acad Sci U S A; 1994 Jan 04; 91(1):167-71. PubMed ID: 7506413
    [Abstract] [Full Text] [Related]

  • 14. Multiple binding sites in the growth factor receptor Xmrk mediate binding to p59fyn, GRB2 and Shc.
    Wellbrock C, Schartl M.
    Eur J Biochem; 1999 Feb 04; 260(1):275-83. PubMed ID: 10091608
    [Abstract] [Full Text] [Related]

  • 15. Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors.
    Suen KL, Bustelo XR, Pawson T, Barbacid M.
    Mol Cell Biol; 1993 Sep 04; 13(9):5500-12. PubMed ID: 7689150
    [Abstract] [Full Text] [Related]

  • 16. Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.
    Nguyen L, Holgado-Madruga M, Maroun C, Fixman ED, Kamikura D, Fournier T, Charest A, Tremblay ML, Wong AJ, Park M.
    J Biol Chem; 1997 Aug 15; 272(33):20811-9. PubMed ID: 9252406
    [Abstract] [Full Text] [Related]

  • 17. Activation of the JNK pathway is essential for transformation by the Met oncogene.
    Rodrigues GA, Park M, Schlessinger J.
    EMBO J; 1997 May 15; 16(10):2634-45. PubMed ID: 9184210
    [Abstract] [Full Text] [Related]

  • 18. Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis.
    Bardelli A, Basile ML, Audero E, Giordano S, Wennström S, Ménard S, Comoglio PM, Ponzetto C.
    Oncogene; 1999 Feb 04; 18(5):1139-46. PubMed ID: 10022119
    [Abstract] [Full Text] [Related]

  • 19. Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.
    Fixman ED, Holgado-Madruga M, Nguyen L, Kamikura DM, Fournier TM, Wong AJ, Park M.
    J Biol Chem; 1997 Aug 08; 272(32):20167-72. PubMed ID: 9242692
    [Abstract] [Full Text] [Related]

  • 20. The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein.
    Pelicci G, Giordano S, Zhen Z, Salcini AE, Lanfrancone L, Bardelli A, Panayotou G, Waterfield MD, Ponzetto C, Pelicci PG.
    Oncogene; 1995 Apr 20; 10(8):1631-8. PubMed ID: 7731718
    [Abstract] [Full Text] [Related]

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