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Journal Abstract Search

111 related items for PubMed ID: 8667362

  • 1. Inhibition of DNA topoisomerase II by azaelliptitoxins functionalized in the variable substituent domain.
    Tepe JJ, Madalengoitia JS, Slunt KM, Werbovetz KW, Spoors PG, Macdonald TL.
    J Med Chem; 1996 May 24; 39(11):2188-96. PubMed ID: 8667362
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  • 2. Azatoxin is a mechanistic hybrid of the topoisomerase II-targeted anticancer drugs etoposide and ellipticine.
    Cline SD, Macdonald TL, Osheroff N.
    Biochemistry; 1997 Oct 21; 36(42):13095-101. PubMed ID: 9335572
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  • 3. Synthesis, cytotoxic activity, DNA topoisomerase-II inhibition, molecular modeling and structure-activity relationship of 9-anilinothiazolo[5,4-b]quinoline derivatives.
    Loza-Mejía MA, Olvera-Vázquez S, Maldonado-Hernández K, Guadarrama-Salgado T, González-Sánchez I, Rodríguez-Hernández F, Solano JD, Rodríguez-Sotres R, Lira-Rocha A.
    Bioorg Med Chem; 2009 May 01; 17(9):3266-77. PubMed ID: 19364657
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  • 4. Rational design and molecular effects of a new topoisomerase II inhibitor, azatoxin.
    Leteurtre F, Madalengoitia J, Orr A, Guzi TJ, Lehnert E, Macdonald T, Pommier Y.
    Cancer Res; 1992 Aug 15; 52(16):4478-83. PubMed ID: 1322792
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  • 6. The 1'-substituent on the anilino ring of the antitumor drug amsacrine is a critical element for topoisomerase II inhibition and cytotoxicity.
    Rene B, Fosse P, Khelifa T, Jacquemin-Sablon A, Bailly C.
    Mol Pharmacol; 1996 Feb 15; 49(2):343-50. PubMed ID: 8632768
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  • 14. Benzothiopyranoindole-based antiproliferative agents: synthesis, cytotoxicity, nucleic acids interaction, and topoisomerases inhibition properties.
    Dalla Via L, Magno SM, Gia O, Marini AM, Da Settimo F, Salerno S, La Motta C, Simorini F, Taliani S, Lavecchia A, Di Giovanni C, Brancato G, Barone V, Novellino E.
    J Med Chem; 2009 Sep 10; 52(17):5429-41. PubMed ID: 19725581
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  • 15. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA, Spicer JA, Atwell GJ, Finlay GJ, Baguley BC, Denny WA.
    J Med Chem; 1999 Jul 01; 42(13):2383-93. PubMed ID: 10395479
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  • 16. Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity.
    Choi SJ, Park HJ, Lee SK, Kim SW, Han G, Choo HY.
    Bioorg Med Chem; 2006 Feb 15; 14(4):1229-35. PubMed ID: 16242334
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  • 18. Antitumor agents. Part 230: C4'-esters of GL-331 as cytotoxic agents and DNA topoisomerase II inhibitors.
    Han S, Xiao Z, Bastow KF, Lee KH.
    Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2979-82. PubMed ID: 15125972
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  • 19. Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives.
    Bacherikov VA, Chang JY, Lin YW, Chen CH, Pan WY, Dong H, Lee RZ, Chou TC, Su TL.
    Bioorg Med Chem; 2005 Dec 01; 13(23):6513-20. PubMed ID: 16140018
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  • 20. Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.
    Cho SJ, Kashiwada Y, Bastow KF, Cheng YC, Lee KH.
    J Med Chem; 1996 Mar 29; 39(7):1396-402. PubMed ID: 8691469
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