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Journal Abstract Search

919 related items for PubMed ID: 8667426

  • 1. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
    Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.
    J Natl Cancer Inst; 1996 Jul 17; 88(14):956-65. PubMed ID: 8667426
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  • 2. A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01.
    Eastman A, Kohn EA, Brown MK, Rathman J, Livingstone M, Blank DH, Gribble GW.
    Mol Cancer Ther; 2002 Oct 17; 1(12):1067-78. PubMed ID: 12481430
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  • 3. UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation.
    Sugiyama K, Shimizu M, Akiyama T, Tamaoki T, Yamaguchi K, Takahashi R, Eastman A, Akinaga S.
    Int J Cancer; 2000 Mar 01; 85(5):703-9. PubMed ID: 10699952
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  • 4. Tetrandrine: a potent abrogator of G2 checkpoint function in tumor cells and its mechanism.
    Sun XC, Cheng HY, Deng YX, Shao RG, Ma J.
    Biomed Environ Sci; 2007 Dec 01; 20(6):495-501. PubMed ID: 18348409
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  • 8. Enhancement of cisplatin-induced cytotoxicity by 7-hydroxystaurosporine (UCN-01), a new G2-checkpoint inhibitor.
    Bunch RT, Eastman A.
    Clin Cancer Res; 1996 May 01; 2(5):791-7. PubMed ID: 9816232
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  • 9. [Potentiation of radiosensitivity by staurosporine associated with abrogation of G2 phase arrest].
    Sun XC, Wang JJ, Zhen YS, Shao RG.
    Yao Xue Xue Bao; 2002 Jun 01; 37(6):419-23. PubMed ID: 12579796
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  • 10. Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe.
    Tse AN, Schwartz GK.
    Cancer Res; 2004 Sep 15; 64(18):6635-44. PubMed ID: 15374978
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  • 11. [Abrogation effect of UCN-01 on radiation-induced G2 phase arrest of tumor cells and its mechanism].
    Hui ZG, Li YX, Yang WZ, Yu ZH.
    Ai Zheng; 2005 Jan 15; 24(1):1-6. PubMed ID: 15642191
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  • 12. 7-Hydroxystaurosporine (UCN-01) causes redistribution of proliferating cell nuclear antigen and abrogates cisplatin-induced S-phase arrest in Chinese hamster ovary cells.
    Bunch RT, Eastman A.
    Cell Growth Differ; 1997 Jul 15; 8(7):779-88. PubMed ID: 9218872
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  • 13. Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines.
    Lee SI, Brown MK, Eastman A.
    Biochem Pharmacol; 1999 Dec 01; 58(11):1713-21. PubMed ID: 10571245
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  • 14. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y, Berger MS, Pieper RO.
    Cancer Res; 2001 Aug 01; 61(15):5843-9. PubMed ID: 11479224
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  • 19. Differential effects of UCN-01, staurosporine and CGP 41 251 on cell cycle progression and CDC2/cyclin B1 regulation in A431 cells synchronized at M phase by nocodazole.
    Akiyama T, Shimizu M, Okabe M, Tamaoki T, Akinaga S.
    Anticancer Drugs; 1999 Jan 01; 10(1):67-78. PubMed ID: 10194549
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  • 20. Loss of p53 induces M-phase retardation following G2 DNA damage checkpoint abrogation.
    Minemoto Y, Uchida S, Ohtsubo M, Shimura M, Sasagawa T, Hirata M, Nakagama H, Ishizaka Y, Yamashita K.
    Arch Biochem Biophys; 2003 Apr 01; 412(1):13-9. PubMed ID: 12646262
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