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153 related items for PubMed ID: 8674048

  • 21. Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression.
    Yu R, Jiao JJ, Duh JL, Gudehithlu K, Tan TH, Kong AN.
    Carcinogenesis; 1997 Feb; 18(2):451-6. PubMed ID: 9054642
    [Abstract] [Full Text] [Related]

  • 22. Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation.
    Satyan KS, Swamy N, Dizon DS, Singh R, Granai CO, Brard L.
    Gynecol Oncol; 2006 Oct; 103(1):261-70. PubMed ID: 16624391
    [Abstract] [Full Text] [Related]

  • 23. Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
    Yan H, Zhu Y, Liu B, Wu H, Li Y, Wu X, Zhou Q, Xu K.
    Br J Nutr; 2011 Dec; 106(12):1779-91. PubMed ID: 21733335
    [Abstract] [Full Text] [Related]

  • 24. Differential hepatic GSTA2 expression of arylalkyl isothiocyanates in vivo and in vitro: the molecular mechanism of gene induction by phenethyl isothiocyanate.
    Gum SI, Cho MK.
    Mol Nutr Food Res; 2013 Dec; 57(12):2223-32. PubMed ID: 24039128
    [Abstract] [Full Text] [Related]

  • 25. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN.
    Mol Cancer Ther; 2006 Aug; 5(8):1918-26. PubMed ID: 16928811
    [Abstract] [Full Text] [Related]

  • 26. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
    Yang YM, Conaway CC, Chiao JW, Wang CX, Amin S, Whysner J, Dai W, Reinhardt J, Chung FL.
    Cancer Res; 2002 Jan 01; 62(1):2-7. PubMed ID: 11782348
    [Abstract] [Full Text] [Related]

  • 27. Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2+ and protein kinase C in endothelin-stimulated Rat-1 cells.
    Cadwallader K, Beltman J, McCormick F, Cook S.
    Biochem J; 1997 Feb 01; 321 ( Pt 3)(Pt 3):795-804. PubMed ID: 9032468
    [Abstract] [Full Text] [Related]

  • 28. c-jun/AP-1 activation does not affect the antiproliferative activity of phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent.
    Yao S, Zhang Y, Li J.
    Mol Carcinog; 2006 Aug 01; 45(8):605-12. PubMed ID: 16652374
    [Abstract] [Full Text] [Related]

  • 29. Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.
    Yu R, Tan TH, Kong AN.
    J Biol Chem; 1997 Nov 14; 272(46):28962-70. PubMed ID: 9360968
    [Abstract] [Full Text] [Related]

  • 30. Differential response of four human livers to modulation of phase II enzyme systems by the chemopreventive phytochemical phenethyl isothiocyanate.
    Konsue N, Ioannides C.
    Mol Nutr Food Res; 2010 Oct 14; 54(10):1477-85. PubMed ID: 20440691
    [Abstract] [Full Text] [Related]

  • 31. Effect of β-phenylethyl isothiocyanate from cruciferous vegetables on growth inhibition and apoptosis of cervical cancer cells through the induction of death receptors 4 and 5.
    Huong le D, Shim JH, Choi KH, Shin JA, Choi ES, Kim HS, Lee SJ, Kim SJ, Cho NP, Cho SD.
    J Agric Food Chem; 2011 Aug 10; 59(15):8124-31. PubMed ID: 21702500
    [Abstract] [Full Text] [Related]

  • 32. Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin.
    Wang X, Govind S, Sajankila SP, Mi L, Roy R, Chung FL.
    Mol Nutr Food Res; 2011 Oct 10; 55(10):1572-81. PubMed ID: 21595016
    [Abstract] [Full Text] [Related]

  • 33. Regulation of c-Jun N-terminal kinase activation in hydrogen peroxide induced neurotoxicity.
    Wang W, Hou XY, Gao C, Liu Y, Zong YY, Zhang GY.
    J Neurocytol; 2003 Feb 10; 32(2):143-51. PubMed ID: 14707549
    [Abstract] [Full Text] [Related]

  • 34. Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).
    Kong AN, Owuor E, Yu R, Hebbar V, Chen C, Hu R, Mandlekar S.
    Drug Metab Rev; 2001 Feb 10; 33(3-4):255-71. PubMed ID: 11768769
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  • 35. Pharmacodynamics and toxicodynamics of drug action: signaling in cell survival and cell death.
    Kong AN, Mandlekar S, Yu R, Lei W, Fasanmande A.
    Pharm Res; 1999 Jun 10; 16(6):790-8. PubMed ID: 10397596
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  • 36. Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts.
    MacKenna DA, Dolfi F, Vuori K, Ruoslahti E.
    J Clin Invest; 1998 Jan 15; 101(2):301-10. PubMed ID: 9435301
    [Abstract] [Full Text] [Related]

  • 37. Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase.
    Chen YR, Han J, Kori R, Kong AN, Tan TH.
    J Biol Chem; 2002 Oct 18; 277(42):39334-42. PubMed ID: 12171915
    [Abstract] [Full Text] [Related]

  • 38. Phenethyl Isothiocyanate (PEITC) and Benzyl Isothiocyanate (BITC) Inhibit Human Melanoma A375.S2 Cell Migration and Invasion by Affecting MAPK Signaling Pathway In Vitro.
    Ma YS, Hsiao YT, Lin JJ, Liao CL, Lin CC, Chung JG.
    Anticancer Res; 2017 Nov 18; 37(11):6223-6234. PubMed ID: 29061805
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  • 39. Hematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascade.
    Zhou G, Lee SC, Yao Z, Tan TH.
    J Biol Chem; 1999 May 07; 274(19):13133-8. PubMed ID: 10224067
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  • 40. Advances in molecular signaling mechanisms of β-phenethyl isothiocyanate antitumor effects.
    Qin CZ, Zhang X, Wu LX, Wen CJ, Hu L, Lv QL, Shen DY, Zhou HH.
    J Agric Food Chem; 2015 Apr 08; 63(13):3311-22. PubMed ID: 25798652
    [Abstract] [Full Text] [Related]

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