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626 related items for PubMed ID: 8674051

  • 21. Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
    Chae YH, Yun CH, Guengerich FP, Kadlubar FF, el-Bayoumy K.
    Cancer Res; 1993 May 01; 53(9):2028-34. PubMed ID: 8481905
    [Abstract] [Full Text] [Related]

  • 22. Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens.
    Yamazaki Y, Fujita K, Nakayama K, Suzuki A, Nakamura K, Yamazaki H, Kamataki T.
    Mutat Res; 2004 Aug 08; 562(1-2):151-62. PubMed ID: 15279838
    [Abstract] [Full Text] [Related]

  • 23. Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.
    Shimada T, Murayama N, Yamazaki H, Tanaka K, Takenaka S, Komori M, Kim D, Guengerich FP.
    Chem Res Toxicol; 2013 Apr 15; 26(4):529-37. PubMed ID: 23432465
    [Abstract] [Full Text] [Related]

  • 24. Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens.
    Shimada T, Yamazaki H, Mimura M, Guengerich FP.
    Mutat Res; 1992 Dec 16; 284(2):233-41. PubMed ID: 1281274
    [Abstract] [Full Text] [Related]

  • 25. High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase.
    Sengstag C, Eugster HP, Würgler FE.
    Carcinogenesis; 1994 May 16; 15(5):837-43. PubMed ID: 8200084
    [Abstract] [Full Text] [Related]

  • 26. Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae.
    Brian WR, Sari MA, Iwasaki M, Shimada T, Kaminsky LS, Guengerich FP.
    Biochemistry; 1990 Dec 25; 29(51):11280-92. PubMed ID: 2271712
    [Abstract] [Full Text] [Related]

  • 27. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
    Yamazaki H, Mimura M, Oda Y, Inui Y, Shiraga T, Iwasaki K, Guengerich FP, Shimada T.
    Carcinogenesis; 1993 Jul 25; 14(7):1271-8. PubMed ID: 8330339
    [Abstract] [Full Text] [Related]

  • 28. Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H, Shimada T.
    Biochem Pharmacol; 1992 Sep 01; 44(5):913-20. PubMed ID: 1530660
    [Abstract] [Full Text] [Related]

  • 29. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
    Jiang H, Shen YM, Quinn AM, Penning TM.
    Chem Res Toxicol; 2005 Feb 01; 18(2):365-74. PubMed ID: 15720144
    [Abstract] [Full Text] [Related]

  • 30. Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
    Shou M, Krausz KW, Gonzalez FJ, Gelboin HV.
    Arch Biochem Biophys; 1996 Apr 01; 328(1):201-7. PubMed ID: 8638931
    [Abstract] [Full Text] [Related]

  • 31. Use of a newly developed tester strain Salmonella typhimurium NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes.
    Yamazaki H, Oda Y, Shimada T.
    Mutat Res; 1992 Oct 01; 272(2):183-92. PubMed ID: 1383750
    [Abstract] [Full Text] [Related]

  • 32. Activation of procarcinogens by human cytochrome P450 enzymes expressed in Escherichia coli. Simplified bacterial systems for genotoxicity assays.
    Shimada T, Gillam EM, Sandhu P, Guo Z, Tukey RH, Guengerich FP.
    Carcinogenesis; 1994 Nov 01; 15(11):2523-9. PubMed ID: 7955101
    [Abstract] [Full Text] [Related]

  • 33. Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.
    Shimada T, Okuda Y.
    Biochem Pharmacol; 1988 Feb 01; 37(3):459-65. PubMed ID: 3337745
    [Abstract] [Full Text] [Related]

  • 34. A new selective and potent inhibitor of human cytochrome P450 1B1 and its application to antimutagenesis.
    Chun YJ, Kim S, Kim D, Lee SK, Guengerich FP.
    Cancer Res; 2001 Nov 15; 61(22):8164-70. PubMed ID: 11719446
    [Abstract] [Full Text] [Related]

  • 35. Catalytic properties of polymorphic human cytochrome P450 1B1 variants.
    Shimada T, Watanabe J, Kawajiri K, Sutter TR, Guengerich FP, Gillam EM, Inoue K.
    Carcinogenesis; 1999 Aug 15; 20(8):1607-13. PubMed ID: 10426814
    [Abstract] [Full Text] [Related]

  • 36. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ, Constable A, Richoz J, Varga N, Markovic J, Martin MV, Guengerich FP.
    Chem Res Toxicol; 1998 Aug 15; 11(8):925-36. PubMed ID: 9705755
    [Abstract] [Full Text] [Related]

  • 37. Studies on covalent binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to cytochromes P-450 LM2 and LM4 and NADPH-cytochrome P-450 reductase.
    Deutsch J, Vatsis KP, Leutz JC, Coon MJ, Gelboin HV.
    Xenobiotica; 1989 Dec 15; 19(12):1421-35. PubMed ID: 2515665
    [Abstract] [Full Text] [Related]

  • 38. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
    Aryal P, Terashita T, Guengerich FP, Shimada T, Oda Y.
    Environ Mol Mutagen; 2000 Dec 15; 36(2):121-6. PubMed ID: 11013410
    [Abstract] [Full Text] [Related]

  • 39. Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.
    Shimada T, Yamazaki H, Foroozesh M, Hopkins NE, Alworth WL, Guengerich FP.
    Chem Res Toxicol; 1998 Sep 15; 11(9):1048-56. PubMed ID: 9760279
    [Abstract] [Full Text] [Related]

  • 40. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
    Oda Y, Watanabe T, Terao Y, Nukaya H, Wakabayashi K.
    Mutat Res; 2008 Jun 30; 654(1):52-7. PubMed ID: 18562244
    [Abstract] [Full Text] [Related]

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