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194 related items for PubMed ID: 8683995

  • 1. Effect of AS101 on bryostatin 1-mediated differentiation induction, cell cycle arrest, and modulation of drug-induced apoptosis in human myeloid leukemia cells.
    Rao AS, Freemerman AJ, Jarvis WD, Chelliah J, Bear HD, Mikkelsen R, Grant S.
    Leukemia; 1996 Jul; 10(7):1150-8. PubMed ID: 8683995
    [Abstract] [Full Text] [Related]

  • 2. Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc.
    Chelliah J, Freemerman AJ, Wu-Pong S, Jarvis WD, Grant S.
    Biochem Pharmacol; 1997 Sep 01; 54(5):563-73. PubMed ID: 9337072
    [Abstract] [Full Text] [Related]

  • 3. Effects of bryostatin 1 and calcium ionophore (A23187) on apoptosis and differentiation in human myeloid leukemia cells (HL-60) following 1-beta-D-arabinofuranosylcytosine exposure.
    Vrana JA, Rao AS, Wang Z, Jarvis WD, Grant S.
    Int J Oncol; 1998 Apr 01; 12(4):927-34. PubMed ID: 9499457
    [Abstract] [Full Text] [Related]

  • 4. Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: relationship to differentiation and ara-C-induced apoptosis.
    Grant S, Turner AJ, Freemerman AJ, Wang Z, Kramer L, Jarvis WD.
    Exp Cell Res; 1996 Oct 10; 228(1):65-75. PubMed ID: 8892972
    [Abstract] [Full Text] [Related]

  • 5. Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.
    Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S.
    Mol Pharmacol; 1997 Dec 10; 52(6):1000-9. PubMed ID: 9396780
    [Abstract] [Full Text] [Related]

  • 6. Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
    Grant S, Jarvis WD, Swerdlow PS, Turner AJ, Traylor RS, Wallace HJ, Lin PS, Pettit GR, Gewirtz DA.
    Cancer Res; 1992 Nov 15; 52(22):6270-8. PubMed ID: 1423273
    [Abstract] [Full Text] [Related]

  • 7. Evidence of a functional role for the cyclin-dependent kinase inhibitor p21(WAF1/CIP1/MDA6) in the reciprocal regulation of PKC activator-induced apoptosis and differentation in human myelomonocytic leukemia cells.
    Wang Z, Su ZZ, Fisher PB, Wang S, VanTuyle G, Grant S.
    Exp Cell Res; 1998 Oct 10; 244(1):105-16. PubMed ID: 9770354
    [Abstract] [Full Text] [Related]

  • 8. Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937).
    Vrana JA, Saunders AM, Chellappan SP, Grant S.
    Differentiation; 1998 May 10; 63(1):33-42. PubMed ID: 9615391
    [Abstract] [Full Text] [Related]

  • 9. Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms.
    Wang S, Wang Z, Grant S.
    Mol Pharmacol; 2003 Jan 10; 63(1):232-42. PubMed ID: 12488556
    [Abstract] [Full Text] [Related]

  • 10. Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells.
    Jarvis WD, Povirk LF, Turner AJ, Traylor RS, Gewirtz DA, Pettit GR, Grant S.
    Biochem Pharmacol; 1994 Mar 02; 47(5):839-52. PubMed ID: 8135859
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol.
    Cartee L, Maggio SC, Smith R, Sankala HM, Dent P, Grant S.
    Mol Cancer Ther; 2003 Jan 02; 2(1):83-93. PubMed ID: 12533676
    [Abstract] [Full Text] [Related]

  • 12. 1alpha,25-dihydroxyvitamin D3 and bryostatin-1 synergize to induce monocytic differentiation of NB4 acute promyelocytic leukemia cells by modulating cell cycle progression.
    Clark CS, Konyer JE, Meckling KA.
    Exp Cell Res; 2004 Mar 10; 294(1):301-11. PubMed ID: 14980523
    [Abstract] [Full Text] [Related]

  • 13. Induction of apoptosis and differentiation by fludarabine in human leukemia cells (U937): interactions with the macrocyclic lactone bryostatin 1.
    Vrana JA, Wang Z, Rao AS, Tang L, Chen JH, Kramer LB, Grant S.
    Leukemia; 1999 Jul 10; 13(7):1046-55. PubMed ID: 10400420
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation.
    Vrana JA, Kramer LB, Saunders AM, Zhang XF, Dent P, Povirk LF, Grant S.
    Biochem Pharmacol; 1999 Jul 01; 58(1):121-31. PubMed ID: 10403525
    [Abstract] [Full Text] [Related]

  • 15. Synergistic effect of AS101 and Bryostatin-1 on myeloid leukemia cell differentiation in vitro and in an animal model.
    Hayun M, Okun E, Hayun R, Gafter U, Albeck M, Longo DL, Sredni B.
    Leukemia; 2007 Jul 01; 21(7):1504-13. PubMed ID: 17508000
    [Abstract] [Full Text] [Related]

  • 16. Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells.
    Wang S, Wang Z, Dent P, Grant S.
    Blood; 2003 May 01; 101(9):3648-57. PubMed ID: 12522001
    [Abstract] [Full Text] [Related]

  • 17. In vitro effects of bryostatin 1 on the metabolism and cytotoxicity of 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
    Grant S, Boise L, Westin E, Howe C, Pettit GR, Turner A, McCrady C.
    Biochem Pharmacol; 1991 Jul 25; 42(4):853-67. PubMed ID: 1867641
    [Abstract] [Full Text] [Related]

  • 18. Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling.
    Jarvis WD, Fornari FA, Tombes RM, Erukulla RK, Bittman R, Schwartz GK, Dent P, Grant S.
    Mol Pharmacol; 1998 Nov 25; 54(5):844-56. PubMed ID: 9804619
    [Abstract] [Full Text] [Related]

  • 19. Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60).
    Freemerman AJ, Vrana JA, Tombes RM, Jiang H, Chellappan SP, Fisher PB, Grant S.
    Leukemia; 1997 Apr 25; 11(4):504-13. PubMed ID: 9096690
    [Abstract] [Full Text] [Related]

  • 20. Evidence of a functional role for the cyclin-dependent kinase inhibitor p21CIP1 in leukemic cell (U937) differentiation induced by low concentrations of 1-beta-D-arabinofuranosylcytosine.
    Wang Z, Wang S, Fisher PB, Dent P, Grant S.
    Differentiation; 2000 Aug 25; 66(1):1-13. PubMed ID: 10997587
    [Abstract] [Full Text] [Related]

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