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Journal Abstract Search

558 related items for PubMed ID: 8684406

  • 1. Revalidation of the in vitro alkaline elution/rat hepatocyte assay for DNA damage: improved criteria for assessment of cytotoxicity and genotoxicity and results for 81 compounds.
    Storer RD, McKelvey TW, Kraynak AR, Elia MC, Barnum JE, Harmon LS, Nichols WW, DeLuca JG.
    Mutat Res; 1996 Jun 12; 368(2):59-101. PubMed ID: 8684406
    [Abstract] [Full Text] [Related]

  • 2. Cytotoxicity as measured by trypan blue as a potentially confounding variable in the in vitro alkaline elution/rat hepatocyte assay.
    Elia MC, Storer RD, Harmon LS, Kraynak AR, McKelvey TW, Hertzog PR, Keenan KP, DeLuca JG, Nichols WW.
    Mutat Res; 1993 Jun 12; 291(3):193-205. PubMed ID: 7685060
    [Abstract] [Full Text] [Related]

  • 3. Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assays.
    Elia MC, Storer RD, McKelvey TW, Kraynak AR, Barnum JE, Harmon LS, DeLuca JG, Nichols WW.
    Environ Mol Mutagen; 1994 Jun 12; 24(3):181-91. PubMed ID: 7957122
    [Abstract] [Full Text] [Related]

  • 4. Validation of a high-throughput in vitro alkaline elution/rat hepatocyte assay for DNA damage.
    Gealy R, Wright-Bourque JL, Kraynak AR, McKelvey TW, Barnum JE, Storer RD.
    Mutat Res; 2007 Apr 20; 629(1):49-63. PubMed ID: 17306613
    [Abstract] [Full Text] [Related]

  • 5. Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential.
    Sina JF, Bean CL, Dysart GR, Taylor VI, Bradley MO.
    Mutat Res; 1983 Aug 20; 113(5):357-91. PubMed ID: 6877265
    [Abstract] [Full Text] [Related]

  • 6. Investigation of the positive response of ethyl acrylate in the mouse lymphoma genotoxicity assay.
    Ciaccio PJ, Gicquel E, O'Neill PJ, Scribner HE, Vandenberghe YL.
    Toxicol Sci; 1998 Dec 20; 46(2):324-32. PubMed ID: 10048136
    [Abstract] [Full Text] [Related]

  • 7. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
    Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P.
    Mutat Res; 2007 Mar 30; 628(1):31-55. PubMed ID: 17293159
    [Abstract] [Full Text] [Related]

  • 8. Occupational hazard evaluation of p-bromobenzyl bromide from tests for genotoxicity.
    Sargent EV, Sina JF, Barnum JE, Storer RD, Johnson TE, Galloway SM, Prato MG, Kirsten NN, Naumann BD.
    Drug Chem Toxicol; 1999 Nov 30; 22(4):583-93. PubMed ID: 10536750
    [Abstract] [Full Text] [Related]

  • 9. The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database.
    Sasaki YF, Sekihashi K, Izumiyama F, Nishidate E, Saga A, Ishida K, Tsuda S.
    Crit Rev Toxicol; 2000 Nov 30; 30(6):629-799. PubMed ID: 11145306
    [Abstract] [Full Text] [Related]

  • 10. In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds.
    Nesslany F, Zennouche N, Simar-Meintières S, Talahari I, Nkili-Mboui EN, Marzin D.
    Mutat Res; 2007 Jun 15; 630(1-2):28-41. PubMed ID: 17507283
    [Abstract] [Full Text] [Related]

  • 11. Discrimination between genotoxicity and cytotoxicity in the induction of DNA double-strand breaks in cells treated with etoposide, melphalan, cisplatin, potassium cyanide, Triton X-100, and gamma-irradiation.
    Vock EH, Lutz WK, Hormes P, Hoffmann HD, Vamvakas S.
    Mutat Res; 1998 Feb 23; 413(1):83-94. PubMed ID: 9602861
    [Abstract] [Full Text] [Related]

  • 12. The alkaline single cell gel electrophoresis assay with mouse multiple organs: results with 30 aromatic amines evaluated by the IARC and U.S. NTP.
    Sasaki YF, Fujikawa K, Ishida K, Kawamura N, Nishikawa Y, Ohta S, Satoh M, Madarame H, Ueno S, Susa N, Matsusaka N, Tsuda S.
    Mutat Res; 1999 Mar 15; 440(1):1-18. PubMed ID: 10095124
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity.
    Kirkland D, Aardema M, Henderson L, Müller L.
    Mutat Res; 2005 Jul 04; 584(1-2):1-256. PubMed ID: 15979392
    [Abstract] [Full Text] [Related]

  • 14. In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronucleus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: a structure-activity relationship (QSAR) analysis of the genotoxic and cytotoxic potential.
    Tafazoli M, Baeten A, Geerlings P, Kirsch-Volders M.
    Mutagenesis; 1998 Mar 04; 13(2):115-26. PubMed ID: 9568582
    [Abstract] [Full Text] [Related]

  • 15. Genotoxicity screening via the γH2AX by flow assay.
    Smart DJ, Ahmedi KP, Harvey JS, Lynch AM.
    Mutat Res; 2011 Oct 01; 715(1-2):25-31. PubMed ID: 21824484
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of a genotoxicity test measuring DNA-strand breaks in mouse lymphoma cells by alkaline unwinding and hydroxyapatite elution.
    Garberg P, Akerblom EL, Bolcsfoldi G.
    Mutat Res; 1988 Jun 01; 203(3):155-76. PubMed ID: 2836728
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles.
    Kirkland D, Aardema M, Müller L, Makoto H.
    Mutat Res; 2006 Sep 19; 608(1):29-42. PubMed ID: 16769241
    [Abstract] [Full Text] [Related]

  • 18. Genotoxicity of environmental agents assessed by the alkaline comet assay.
    Møller P.
    Basic Clin Pharmacol Toxicol; 2005 Sep 19; 96 Suppl 1():1-42. PubMed ID: 15859009
    [Abstract] [Full Text] [Related]

  • 19. The ability of the Comet assay to discriminate between genotoxins and cytotoxins.
    Henderson L, Wolfreys A, Fedyk J, Bourner C, Windebank S.
    Mutagenesis; 1998 Jan 19; 13(1):89-94. PubMed ID: 9491401
    [Abstract] [Full Text] [Related]

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