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Journal Abstract Search


72 related items for PubMed ID: 8689950

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  • 3. O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings.
    Dolan ME, Roy SK, Fasanmade AA, Paras PR, Schilsky RL, Ratain MJ.
    J Clin Oncol; 1998 May; 16(5):1803-10. PubMed ID: 9586894
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  • 6. Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and analogues in nonhuman primates.
    Long L, Berg SL, Roy SK, McCully CL, Song-Yoo HW, Moschel RC, Balis FM, Dolan ME.
    Clin Cancer Res; 2000 Sep; 6(9):3662-9. PubMed ID: 10999759
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  • 7. Pharmacokinetics of oral O6-benzylguanine and evidence of interaction with oral ketoconazole in the rat.
    Ewesuedo RB, Dolan ME.
    Cancer Chemother Pharmacol; 2000 Sep; 46(2):150-5. PubMed ID: 10972485
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  • 9. Pharmacokinetics and metabolism in rats of 2,4-diamino-6-benzyloxy-5- nitrosopyrimidine, an inactivator of O6-alkylguanine-DNA alkyltransferase.
    Roy SK, Moschel RC, Dolan ME.
    Drug Metab Dispos; 1996 Nov; 24(11):1205-11. PubMed ID: 8937854
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  • 16. Metabolism and disposition of O6-benzyl-2'-deoxyguanosine in Sprague-Dawley rats.
    Kokkinakis DM, Moschel RC, Pegg AE, Dolan ME, Schold SC.
    Chem Res Toxicol; 1994 Nov; 7(6):762-9. PubMed ID: 7696530
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  • 18. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
    Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME.
    J Pharmacol Exp Ther; 2005 Dec; 315(3):1247-55. PubMed ID: 16126841
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  • 19. Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.
    Mitchell RB, Moschel RC, Dolan ME.
    Cancer Res; 1992 Mar 01; 52(5):1171-5. PubMed ID: 1737376
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  • 20. Pharmacokinetics of O(6)-benzylguanine in pediatric patients with central nervous system tumors: a pediatric oncology group study.
    Neville K, Blaney S, Bernstein M, Thompson P, Adams D, Aleksic A, Berg S.
    Clin Cancer Res; 2004 Aug 01; 10(15):5072-5. PubMed ID: 15297409
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