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Journal Abstract Search

214 related items for PubMed ID: 8691429

  • 1. Aristeromycin-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Liu S, Yuan CS, Borchardt RT.
    J Med Chem; 1996 Jun 07; 39(12):2347-53. PubMed ID: 8691429
    [Abstract] [Full Text] [Related]

  • 2. Effects of 4'-modified analogs of aristeromycin on the metabolism of S-adenosyl-L-homocysteine in murine L929 cells.
    Ault-Riché DB, Lee Y, Yuan CS, Hasobe M, Wolfe MS, Borcherding DR, Borchardt RT.
    Mol Pharmacol; 1993 Jun 07; 43(6):989-97. PubMed ID: 8316227
    [Abstract] [Full Text] [Related]

  • 3. The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oxime.
    Huang H, Yuan CS, Wnuk SF, Robins MJ, Borchardt RT.
    Arch Biochem Biophys; 1997 Jul 01; 343(1):109-17. PubMed ID: 9210652
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  • 4. Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine).
    Robins MJ, Wnuk SF, Yang X, Yuan CS, Borchardt RT, Balzarini J, De Clercq E.
    J Med Chem; 1998 Sep 24; 41(20):3857-64. PubMed ID: 9748360
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  • 6. Mechanism of inactivation of S-adenosylhomocysteine hydrolase by (Z)-4',5'-didehydro-5'-deoxy-5'-fluoroadenosine.
    Yuan CS, Yeh J, Liu S, Borchardt RT.
    J Biol Chem; 1993 Aug 15; 268(23):17030-7. PubMed ID: 8349591
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  • 8. Synthesis of homologated halovinyl derivatives from aristeromycin and their inhibition of human placental S-adenosyl-L-homocysteine hydrolase.
    Wnuk SF, Yuan CS, Borchardt RT, Robins MJ.
    Nucleosides Nucleotides; 1998 Aug 15; 17(1-3):99-113. PubMed ID: 9708344
    [Abstract] [Full Text] [Related]

  • 9. Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Liu S, Wnuk SF, Yuan C, Robins MJ, Borchardt RT.
    J Med Chem; 1993 Apr 02; 36(7):883-7. PubMed ID: 8464042
    [Abstract] [Full Text] [Related]

  • 10. Inactivation of S-adenosyl-L-homocysteine hydrolase by amide and ester derivatives of adenosine-5'-carboxylic acid.
    Wnuk SF, Liu S, Yuan CS, Borchardt RT, Robins MJ.
    J Med Chem; 1996 Oct 11; 39(21):4162-6. PubMed ID: 8863793
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  • 12. Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase.
    Jeong LS, Yoo SJ, Lee KM, Koo MJ, Choi WJ, Kim HO, Moon HR, Lee MY, Park JG, Lee SK, Chun MW.
    J Med Chem; 2003 Jan 16; 46(2):201-3. PubMed ID: 12519056
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  • 14. Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine.
    Hasobe M, McKee JG, Ishii H, Cools M, Borchardt RT, De Clercq E.
    Mol Pharmacol; 1989 Sep 16; 36(3):490-6. PubMed ID: 2779528
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
    Ando T, Iwata M, Zulfiqar F, Miyamoto T, Nakanishi M, Kitade Y.
    Bioorg Med Chem; 2008 Apr 01; 16(7):3809-15. PubMed ID: 18295495
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  • 17. Mechanism of inactivation of S-adenosyl-L-homocysteine hydrolase by 5'-deoxy-5'-S-allenylthioadenosine and 5'-deoxy-5'-S-propynylthioadenosine.
    Guillerm G, Guillerm D, Witkowski-Vandenplas C.
    Nucleosides Nucleotides Nucleic Acids; 2001 Apr 01; 20(4-7):685-8. PubMed ID: 11563092
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  • 18. Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: transition-state stabilization and the avoidance of abortive reactions.
    Yang X, Hu Y, Yin DH, Turner MA, Wang M, Borchardt RT, Howell PL, Kuczera K, Schowen RL.
    Biochemistry; 2003 Feb 25; 42(7):1900-9. PubMed ID: 12590576
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  • 19. (E)-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine: a substrate that measures the hydrolytic activity of S-adenosylhomocysteine hydrolase.
    Yuan CS, Wnuk SF, Liu S, Robins MJ, Borchardt RT.
    Biochemistry; 1994 Oct 11; 33(40):12305-11. PubMed ID: 7918452
    [Abstract] [Full Text] [Related]

  • 20. Sulfur extrusion with tin radical: synthesis of 4',5'-didehydro-5'-deoxy-5'-(tributylstannyl)adenosine, an intermediate for potential inhibitors against S-adenosyl homocysteine hydrolase.
    Kumamoto H, Onuma S, Tanaka H.
    J Org Chem; 2004 Jan 09; 69(1):72-8. PubMed ID: 14703380
    [Abstract] [Full Text] [Related]

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