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Journal Abstract Search

497 related items for PubMed ID: 8691457

  • 1. Synthesis and biological activity of 3- and 5-amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone.
    Liu MC, Lin TS, Cory JG, Cory AH, Sartorelli AC.
    J Med Chem; 1996 Jun 21; 39(13):2586-93. PubMed ID: 8691457
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  • 2. Synthesis and antitumor activity of amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone.
    Liu MC, Lin TS, Sartorelli AC.
    J Med Chem; 1992 Oct 02; 35(20):3672-7. PubMed ID: 1433178
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  • 3. Synthesis and antitumor activity of 4- and 5-substituted derivatives of isoquinoline-1-carboxaldehyde thiosemicarbazone.
    Liu MC, Lin TS, Penketh P, Sartorelli AC.
    J Med Chem; 1995 Oct 13; 38(21):4234-43. PubMed ID: 7473550
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  • 6. Inhibitors of ribonucleotide reductase. Comparative effects of amino- and hydroxy-substituted pyridine-2-carboxaldehyde thiosemicarbazones.
    Cory JG, Cory AH, Rappa G, Lorico A, Liu MC, Lin TS, Sartorelli AC.
    Biochem Pharmacol; 1994 Jul 19; 48(2):335-44. PubMed ID: 8053929
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  • 10. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
    Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR.
    J Med Chem; 2007 Jul 26; 50(15):3716-29. PubMed ID: 17602603
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  • 12. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.
    Finch RA, Liu M, Grill SP, Rose WC, Loomis R, Vasquez KM, Cheng Y, Sartorelli AC.
    Biochem Pharmacol; 2000 Apr 15; 59(8):983-91. PubMed ID: 10692563
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  • 13. Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities.
    Son JK, Zhao LX, Basnet A, Thapa P, Karki R, Na Y, Jahng Y, Jeong TC, Jeong BS, Lee CS, Lee ES.
    Eur J Med Chem; 2008 Apr 15; 43(4):675-82. PubMed ID: 17673337
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  • 14. Folate-based inhibitors of thymidylate synthase: synthesis and antitumor activity of gamma-linked sterically hindered dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Bavetsias V, Jackman AL, Marriott JH, Kimbell R, Gibson W, Boyle FT, Bisset GM.
    J Med Chem; 1997 May 09; 40(10):1495-510. PubMed ID: 9154971
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  • 15. Structure-activity relationship of 3-substituted N-(pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene )- piperidine inhibitors of farnesyl-protein transferase: design and synthesis of in vivo active antitumor compounds.
    Njoroge FG, Vibulbhan B, Rane DF, Bishop WR, Petrin J, Patton R, Bryant MS, Chen KJ, Nomeir AA, Lin CC, Liu M, King I, Chen J, Lee S, Yaremko B, Dell J, Lipari P, Malkowski M, Li Z, Catino J, Doll RJ, Girijavallabhan V, Ganguly AK.
    J Med Chem; 1997 Dec 19; 40(26):4290-301. PubMed ID: 9435898
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  • 16. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.
    Richardson DR, Kalinowski DS, Richardson V, Sharpe PC, Lovejoy DB, Islam M, Bernhardt PV.
    J Med Chem; 2009 Mar 12; 52(5):1459-70. PubMed ID: 19216562
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  • 17. The carcinostatic activity of alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones. II. 3-Hydroxypyridine-2-carboxaldehyde thiosemicarbazone.
    French FA, Blanz EJ.
    Cancer Res; 1966 Aug 12; 26(8):1638-40. PubMed ID: 5923162
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  • 18. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Palmer BD, Wilson WR, Anderson RF, Boyd M, Denny WA.
    J Med Chem; 1996 Jun 21; 39(13):2518-28. PubMed ID: 8691449
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  • 19. Cytotoxicity of 2-aldo- and 2-ketopyridine-N(4)-substituted thiosemicarbazones and mode of action in human Tmolt4 cells.
    Hall IH, Barnes BJ, Rowell JE, Shaffer KA, Cho SE, West DX, Stark AM.
    Pharmazie; 2001 Aug 21; 56(8):648-53. PubMed ID: 11534344
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  • 20. Quinazoline antifolate thymidylate synthase inhibitors: gamma-linked L-D, D-D, and D-L dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Bavetsias V, Jackman AL, Kimbell R, Gibson W, Boyle FT, Bisset GM.
    J Med Chem; 1996 Jan 05; 39(1):73-85. PubMed ID: 8568829
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