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189 related items for PubMed ID: 8691640

  • 1. [Separation of methotrexate-polyglutamates by capillary electrophoresis and its application to the measurement of gamma-glutamyl hydrolase activity in human leukemia cells in culture].
    Takemura Y, Kobayashi H, Sekiguchi S.
    Rinsho Byori; 1996 Jan; 44(1):51-6. PubMed ID: 8691640
    [Abstract] [Full Text] [Related]

  • 2. Methotrexate intracellular disposition in acute lymphoblastic leukemia: a mathematical model of gamma-glutamyl hydrolase activity.
    Panetta JC, Wall A, Pui CH, Relling MV, Evans WE.
    Clin Cancer Res; 2002 Jul; 8(7):2423-9. PubMed ID: 12114448
    [Abstract] [Full Text] [Related]

  • 3. Capillary electrophoresis of methotrexate polyglutamates and its application in evaluation of gamma-glutamyl hydrolase activity.
    Waltham MC, Lin S, Li WW, Göker E, Gritsman H, Tong WP, Bertino JR.
    J Chromatogr B Biomed Sci Appl; 1997 Feb 21; 689(2):387-92. PubMed ID: 9080326
    [Abstract] [Full Text] [Related]

  • 4. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
    Panetta JC, Yanishevski Y, Pui CH, Sandlund JT, Rubnitz J, Rivera GK, Ribeiro R, Evans WE, Relling MV.
    Cancer Chemother Pharmacol; 2002 Nov 21; 50(5):419-28. PubMed ID: 12439601
    [Abstract] [Full Text] [Related]

  • 5. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR.
    Oncol Res; 1997 Nov 21; 9(5):259-63. PubMed ID: 9306433
    [Abstract] [Full Text] [Related]

  • 6. The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cells.
    Takemura Y, Kobayashi H, Gibson W, Kimbell R, Miyachi H, Jackman AL.
    Int J Cancer; 1996 Mar 28; 66(1):29-36. PubMed ID: 8608962
    [Abstract] [Full Text] [Related]

  • 7. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J, Chabner BA.
    J Clin Invest; 1983 Sep 28; 72(3):773-8. PubMed ID: 6193143
    [Abstract] [Full Text] [Related]

  • 8. Genotyping of single nucleotide polymorphism in γ-glutamyl hydrolase gene by capillary electrophoresis.
    Cheng HL, Chiou SS, Liao YM, Chen YL, Wu SM.
    Electrophoresis; 2011 Aug 28; 32(15):2021-7. PubMed ID: 21538980
    [Abstract] [Full Text] [Related]

  • 9. Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug.
    Takemura Y, Gibson W, Kimbell R, Kobayashi H, Miyachi H, Jackman AL.
    J Cancer Res Clin Oncol; 1996 Aug 28; 122(2):109-17. PubMed ID: 8576277
    [Abstract] [Full Text] [Related]

  • 10. Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse.
    Samuels LL, Goutas LJ, Priest DG, Piper JR, Sirotnak FM.
    Cancer Res; 1986 May 28; 46(5):2230-5. PubMed ID: 2421872
    [Abstract] [Full Text] [Related]

  • 11. Therapeutic responses in childhood acute lymphoblastic leukemia (ALL) and haplotypes of gamma glutamyl hydrolase (GGH) gene.
    Garcia-Bournissen F, Moghrabi A, Krajinovic M.
    Leuk Res; 2007 Jul 28; 31(7):1023-5. PubMed ID: 16999998
    [No Abstract] [Full Text] [Related]

  • 12. A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells.
    Cheng Q, Wu B, Kager L, Panetta JC, Zheng J, Pui CH, Relling MV, Evans WE.
    Pharmacogenetics; 2004 Aug 28; 14(8):557-67. PubMed ID: 15284538
    [Abstract] [Full Text] [Related]

  • 13. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
    Koizumi S, Curt GA, Fine RL, Griffin JD, Chabner BA.
    J Clin Invest; 1985 Mar 28; 75(3):1008-14. PubMed ID: 2579975
    [Abstract] [Full Text] [Related]

  • 14. Epigenetic regulation of human gamma-glutamyl hydrolase activity in acute lymphoblastic leukemia cells.
    Cheng Q, Cheng C, Crews KR, Ribeiro RC, Pui CH, Relling MV, Evans WE.
    Am J Hum Genet; 2006 Aug 28; 79(2):264-74. PubMed ID: 16826517
    [Abstract] [Full Text] [Related]

  • 15. Evidence for negative feedback of extracellular methotrexate on blasts of acute lymphoblastic leukemia in vitro.
    Hum MC, Smith AK, Lark RH, Winick NJ, Kamen BA.
    Pharmacotherapy; 1997 Aug 28; 17(6):1260-6. PubMed ID: 9399609
    [Abstract] [Full Text] [Related]

  • 16. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
    Barakat RR, Li WW, Lovelace C, Bertino JR.
    Gynecol Oncol; 1993 Oct 28; 51(1):54-60. PubMed ID: 7694891
    [Abstract] [Full Text] [Related]

  • 17. Impairment of methotrexate (MTX)-polyglutamate formation of MTX-resistant K562 cell lines.
    Koizumi S.
    Jpn J Cancer Res; 1988 Nov 28; 79(11):1230-7. PubMed ID: 2465288
    [Abstract] [Full Text] [Related]

  • 18. Role of folylpolyglutamate synthetase in the regulation of methotrexate polyglutamate formation in H35 hepatoma cells.
    Johnson TB, Nair MG, Galivan J.
    Cancer Res; 1988 May 01; 48(9):2426-31. PubMed ID: 2451560
    [Abstract] [Full Text] [Related]

  • 19. Insulin-dependent suppression in glutamyl hydrolase activity and elevated cellular methotrexate polyglutamates.
    Galivan J, Rhee MS.
    Biochem Pharmacol; 1995 Nov 09; 50(10):1659-63. PubMed ID: 7503769
    [Abstract] [Full Text] [Related]

  • 20. Biochemical and growth inhibitory effects of the erythro and threo isomers of gamma-fluoromethotrexate, a methotrexate analogue defective in polyglutamylation.
    McGuire JJ, Graber M, Licato N, Vincenz C, Coward JK, Nimec Z, Galivan J.
    Cancer Res; 1989 Aug 15; 49(16):4517-25. PubMed ID: 2472880
    [Abstract] [Full Text] [Related]

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